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There are 7740 results for: content related to: Parsing out the complexity of RAF inhibitor resistance

  1. You have free access to this content
    Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition

    Pigment Cell & Melanoma Research

    Volume 25, Issue 2, March 2012, Pages: 248–258, W. Deng, Y. N. Vashisht Gopal, A. Scott, G. Chen, S. E. Woodman and M. A. Davies

    Version of Record online : 12 JAN 2012, DOI: 10.1111/j.1755-148X.2011.00950.x

  2. You have full text access to this OnlineOpen article
    Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors

    Pigment Cell & Melanoma Research

    Volume 27, Issue 2, March 2014, Pages: 253–262, Jaehyuk Choi, Sean F. Landrette, Tiffany Wang, Perry Evans, Antonella Bacchiocchi, Robert Bjornson, Elaine Cheng, Amy L. Stiegler, Symon Gathiaka, Orlando Acevedo, Titus J. Boggon, Michael Krauthammer, Ruth Halaban and Tian Xu

    Version of Record online : 6 JAN 2014, DOI: 10.1111/pcmr.12197

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    Mechanisms of intrinsic and acquired resistance to kinase-targeted therapies

    Pigment Cell & Melanoma Research

    Volume 25, Issue 6, November 2012, Pages: 819–831, Shubha Bagrodia, Tod Smeal and Robert T. Abraham

    Version of Record online : 14 SEP 2012, DOI: 10.1111/pcmr.12007

  4. You have full text access to this OnlineOpen article
    ROCK1 is a potential combinatorial drug target for BRAF mutant melanoma

    Molecular Systems Biology

    Volume 10, Issue 12, December 2014, Marjon A Smit, Gianluca Maddalo, Kylie Greig, Linsey M Raaijmakers, Patricia A Possik, Bas van Breukelen, Salvatore Cappadona, Albert JR Heck, AF Maarten Altelaar and Daniel S Peeper

    Version of Record online : 23 DEC 2014, DOI: 10.15252/msb.20145450

  5. The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors

    Pigment Cell & Melanoma Research

    Volume 28, Issue 4, July 2015, Pages: 417–430, Casey G. Langdon, Matthew A. Held, James T. Platt, Katrina Meeth, Pinar Iyidogan, Ramanaiah Mamillapalli, Andrew B. Koo, Michael Klein, Zongzhi Liu, Marcus W. Bosenberg and David F. Stern

    Version of Record online : 6 MAY 2015, DOI: 10.1111/pcmr.12376

  6. Inhibition of mutant BRAF splice variant signaling by next-generation, selective RAF inhibitors

    Pigment Cell & Melanoma Research

    Volume 27, Issue 3, May 2014, Pages: 479–484, Kevin J. Basile, Kaitlyn Le, Edward J. Hartsough and Andrew E. Aplin

    Version of Record online : 10 FEB 2014, DOI: 10.1111/pcmr.12218

  7. Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells

    Pigment Cell & Melanoma Research

    Volume 26, Issue 4, July 2013, Pages: 509–517, Kaitlyn Le, Erik S. Blomain, Ulrich Rodeck and Andrew E. Aplin

    Version of Record online : 8 APR 2013, DOI: 10.1111/pcmr.12092

  8. Actin remodeling confers BRAF inhibitor resistance to melanoma cells through YAP/TAZ activation

    The EMBO Journal

    Volume 35, Issue 5, 1 March 2016, Pages: 462–478, Min Hwan Kim, Jongshin Kim, Hyowon Hong, Si-Hyung Lee, June-Koo Lee, Eunji Jung and Joon Kim

    Version of Record online : 14 DEC 2015, DOI: 10.15252/embj.201592081

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    2011 International Melanoma Congress

    Pigment Cell & Melanoma Research

    Volume 24, Issue 5, October 2011, Pages: 990–1075,

    Version of Record online : 10 OCT 2011, DOI: 10.1111/j.1755-148X.2011.00909.x

  10. Therapeutic resistance resulting from mutations in Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR signaling pathways

    Journal of Cellular Physiology

    Volume 226, Issue 11, November 2011, Pages: 2762–2781, James A. McCubrey, Linda S. Steelman, C. Ruth Kempf, William H. Chappell, Stephen L. Abrams, Franca Stivala, Graziella Malaponte, Ferdinando Nicoletti, Massimo Libra, Jörg Bäsecke, Danijela Maksimovic-Ivanic, Sanja Mijatovic, Giuseppe Montalto, Melchiorre Cervello, Lucio Cocco and Alberto M. Martelli

    Version of Record online : 24 AUG 2011, DOI: 10.1002/jcp.22647

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    Society for Melanoma Research 2013 Congress

    Pigment Cell & Melanoma Research

    Volume 26, Issue 6, November 2013, Pages: 932–1019,

    Version of Record online : 24 OCT 2013, DOI: 10.1111/pcmr.12166

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    Society for Melanoma Research 2012 Congress

    Pigment Cell & Melanoma Research

    Volume 25, Issue 6, November 2012, Pages: 836–903,

    Version of Record online : 19 OCT 2012, DOI: 10.1111/pcmr.12023

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    That which does not kill me makes me stronger; combining ERK1/2 pathway inhibitors and BH3 mimetics to kill tumour cells and prevent acquired resistance

    British Journal of Pharmacology

    Volume 169, Issue 8, August 2013, Pages: 1708–1722, Matthew J Sale and Simon J Cook

    Version of Record online : 26 JUL 2013, DOI: 10.1111/bph.12220

  14. You have full text access to this OnlineOpen article
    Systematic analysis of BRAFV600E melanomas reveals a role for JNK/c-Jun pathway in adaptive resistance to drug-induced apoptosis

    Molecular Systems Biology

    Volume 11, Issue 3, March 2015, Mohammad Fallahi-Sichani, Nathan J Moerke, Mario Niepel, Tinghu Zhang, Nathanael S Gray and Peter K Sorger

    Version of Record online : 26 MAR 2015, DOI: 10.15252/msb.20145877

  15. Enhancing the evaluation of PI3K inhibitors through 3D melanoma models

    Pigment Cell & Melanoma Research

    Volume 29, Issue 3, May 2016, Pages: 317–328, Batool Shannan, Quan Chen, Andrea Watters, Michela Perego, Clemens Krepler, Rakhee Thombre, Ling Li, Geena Rajan, Scott Peterson, Phyllis A. Gimotty, Melissa Wilson, Katherine L. Nathanson, Tara C. Gangadhar, Lynn M. Schuchter, Ashani T. Weeraratna, Meenhard Herlyn and Adina Vultur

    Version of Record online : 21 MAR 2016, DOI: 10.1111/pcmr.12465

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    The plexin C1 receptor promotes acute inflammation

    European Journal of Immunology

    Volume 44, Issue 9, September 2014, Pages: 2648–2658, Klemens König, Linda Marth, Jan Roissant, Tiago Granja, Carla Jennewein, Vasudharani Devanathan, Mariella Schneider, David Köhler, Alexander Zarbock and Peter Rosenberger

    Version of Record online : 30 JUN 2014, DOI: 10.1002/eji.201343968

  17. You have full text access to this OnlineOpen article
    Plx1 is required for chromosomal DNA replication under stressful conditions

    The EMBO Journal

    Volume 27, Issue 6, March 19, 2008, Pages: 876–885, Kristina Trenz, Alessia Errico and Vincenzo Costanzo

    Version of Record online : 28 FEB 2008, DOI: 10.1038/emboj.2008.29

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    Reviewing the somatic genetics of melanoma: from current to future analytical approaches

    Pigment Cell & Melanoma Research

    Volume 25, Issue 2, March 2012, Pages: 144–154, Ken Dutton-Regester and Nicholas K. Hayward

    Version of Record online : 13 FEB 2012, DOI: 10.1111/j.1755-148X.2012.00975.x

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    Melanoma 2010 Congress

    Pigment Cell & Melanoma Research

    Volume 23, Issue 6, December 2010, Pages: 874–1004,

    Version of Record online : 13 OCT 2010, DOI: 10.1111/j.1755-148X.2010.00767.x

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    Targeting RAS/RAF/MEK/ERK signaling in metastatic melanoma

    IUBMB Life

    Volume 65, Issue 9, September 2013, Pages: 748–758, Ao-Xue Wang and Xiao-Yi Qi

    Version of Record online : 29 JUL 2013, DOI: 10.1002/iub.1193