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There are 1410 results for: content related to: In vitro studies of dasatinib, its targets and predictors of sensitivity

  1. Phase I Study of the Effect of Gastric Acid pH Modulators on the Bioavailability of Oral Dasatinib in Healthy Subjects

    The Journal of Clinical Pharmacology

    Volume 49, Issue 6, June 2009, Pages: 700–709, Dr Timothy Eley, Dr Feng R. Luo, Dr Shruti Agrawal, Dr Ashish Sanil, Dr James Manning, Dr Tong Li, Dr Anne Blackwood-Chirchir and Dr Richard Bertz

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270009333854

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    Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors


    Volume 116, Issue 6, 15 March 2010, Pages: 1582–1591, Faye M. Johnson, Shruti Agrawal, Howard Burris, Lee Rosen, Navneet Dhillon, David Hong, Anne Blackwood-Chirchir, Feng R. Luo, Oumar Sy, Sanjeev Kaul and Alberto A. Chiappori

    Version of Record online : 27 JAN 2010, DOI: 10.1002/cncr.24927

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    Dasatinib induces autophagic cell death in human ovarian cancer


    Volume 116, Issue 21, 1 November 2010, Pages: 4980–4990, Xiao-Feng Le, Weiqun Mao, Zhen Lu, Bing Z. Carter and Robert C. Bast Jr

    Version of Record online : 13 JUL 2010, DOI: 10.1002/cncr.25426

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    Dasatinib inhibits B cell receptor signalling in chronic lymphocytic leukaemia but novel combination approaches are required to overcome additional pro-survival microenvironmental signals

    British Journal of Haematology

    Volume 153, Issue 2, April 2011, Pages: 199–211, Alison M. MCCaig, Emilio Cosimo, Michael T. Leach and Alison M. Michie

    Version of Record online : 24 FEB 2011, DOI: 10.1111/j.1365-2141.2010.08507.x

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    Ingredients in Fruit Juices Interact with Dasatinib Through Inhibition of BCRP: A New Mechanism of Beverage–Drug Interaction

    Journal of Pharmaceutical Sciences

    Volume 104, Issue 1, January 2015, Pages: 266–275, Brett Fleisher, Jesse Unum, Jie Shao and Guohua An

    Version of Record online : 21 NOV 2014, DOI: 10.1002/jps.24289

  6. The impact of dasatinib on pregnancy outcomes

    American Journal of Hematology

    Volume 90, Issue 12, December 2015, Pages: 1111–1115, Jorge E. Cortes, Elisabetta Abruzzese, Ekaterina Chelysheva, Mausumee Guha, Nicola Wallis and Jane F. Apperley

    Version of Record online : 12 OCT 2015, DOI: 10.1002/ajh.24186

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    Dasatinib inhibits the proliferation and function of CD4+CD25+ regulatory T cells

    British Journal of Haematology

    Volume 144, Issue 2, January 2009, Pages: 195–205, Fei Fei, Yingzhe Yu, Anita Schmitt, Markus Thomas Rojewski, Baoan Chen, Marlies Götz, Hartmut Döhner, Donald Bunjes and Michael Schmitt

    Version of Record online : 11 NOV 2008, DOI: 10.1111/j.1365-2141.2008.07433.x

  8. Importance of Characterizing Determinants of Variability in Exposure: Application to Dasatinib in Subjects With Chronic Myeloid Leukemia

    The Journal of Clinical Pharmacology

    Volume 48, Issue 11, November 2008, Pages: 1254–1269, Guowei Dai, Marc Pfister, Anne Blackwood-Chirchir and Amit Roy

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008320604

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    Dasatinib treatment for Philadelphia chromosome-positive leukemias


    Volume 115, Issue 7, 1 April 2009, Pages: 1381–1394, Hanna Jean Khoury, François Guilhot, Timothy P. Hughes, Dong-Wook Kim and Jorge E. Cortes

    Version of Record online : 4 FEB 2009, DOI: 10.1002/cncr.24155

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    Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model

    International Journal of Cancer

    Volume 125, Issue 11, 1 December 2009, Pages: 2547–2555, Roberta Vitali, Camillo Mancini, Vincenzo Cesi, Barbara Tanno, Marta Piscitelli, Mariateresa Mancuso, Fabiola Sesti, Emanuela Pasquali, Bruno Calabretta, Carlo Dominici and Giuseppe Raschellà

    Version of Record online : 28 MAY 2009, DOI: 10.1002/ijc.24606

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    Inhibition of calcineurin combined with dasatinib has direct and indirect anti-leukemia effects against BCR-ABL1+ leukemia

    American Journal of Hematology

    Volume 89, Issue 9, September 2014, Pages: 896–903, Lori A. Gardner, Jelena Klawitter, Mark A. Gregory, Vadym Zaberezhnyy, Dmitry Baturin, Daniel A. Pollyea, Naoko Takebe, Uwe Christians, Lia Gore, James DeGregori and Christopher C. Porter

    Version of Record online : 19 JUN 2014, DOI: 10.1002/ajh.23776

  12. Dasatinib inhibits mammary tumour development in a genetically engineered mouse model

    The Journal of Pathology

    Volume 230, Issue 4, August 2013, Pages: 430–440, Saadia A Karim, Helen Creedon, Hitesh Patel, Neil O Carragher, Jennifer P Morton, William J Muller, Thomas RJ Evans, Barry Gusterson, Owen J Sansom and Valerie G Brunton

    Version of Record online : 9 JUL 2013, DOI: 10.1002/path.4202

  13. Fluorescent Visualization of Src by Using Dasatinib-BODIPY


    Volume 15, Issue 9, June 16, 2014, Pages: 1317–1324, Dr. Michael L. Vetter, Dr. Zijuan Zhang, Dr. Shuai Liu, Dr. Jinhua Wang, HaeYeon Cho, Dr. Jianming Zhang, Prof. Wei Zhang, Prof. Nathanael S. Gray and Prof. Priscilla L. Yang

    Version of Record online : 14 MAY 2014, DOI: 10.1002/cbic.201402010

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    Enhancement of natural killer cell effector functions against selected lymphoma and leukemia cell lines by dasatinib

    International Journal of Cancer

    Volume 131, Issue 6, 15 September 2012, Pages: E916–E927, Nicole Hassold, Katharina Seystahl, Kristina Kempf, Doris Urlaub, Michael Zekl, Hermann Einsele, Carsten Watzl, Jörg Wischhusen and Ruth Seggewiss-Bernhardt

    Version of Record online : 4 APR 2012, DOI: 10.1002/ijc.27537

  15. Dasatinib inhibits progenitor cell proliferation from polycythaemia vera

    European Journal of Clinical Investigation

    Volume 38, Issue 8, August 2008, Pages: 578–584, M. Wappl, E. Jaeger, B. Streubel, H. Gisslinger, I. Schwarzinger, P. Valent and L. Oehler

    Version of Record online : 17 JUL 2008, DOI: 10.1111/j.1365-2362.2008.01982.x

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    Dynamics and management of cytopenias associated with dasatinib therapy in patients with chronic myeloid leukemia in chronic phase after imatinib failure


    Volume 115, Issue 17, 1 September 2009, Pages: 3935–3943, Alfonso Quintás-Cardama, Fabio Pires De Souza Santos, Hagop Kantarjian, Susan O'Brien, Stefan Faderl, Ahmed Awais, Gautam Borthakur and Jorge Cortes

    Version of Record online : 10 JUN 2009, DOI: 10.1002/cncr.24432

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    Direct effect of dasatinib on signal transduction pathways associated with a rapid mobilization of cytotoxic lymphocytes

    Cancer Medicine

    Noriyoshi Iriyama, Yoshihiro Hatta and Masami Takei

    Version of Record online : 10 OCT 2016, DOI: 10.1002/cam4.925

  18. Direct effect of dasatinib on proliferation and cytotoxicity of natural killer cells in in vitro study

    Hematological Oncology

    Volume 31, Issue 3, September 2013, Pages: 156–163, Takayoshi Uchiyama, Naoya Sato, Miwako Narita, Akie Yamahira, Minami Iwabuchi, Tatsuo Furukawa, Hirohito Sone and Masuhiro Takahashi

    Version of Record online : 29 OCT 2012, DOI: 10.1002/hon.2034

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    The tyrosine kinase inhibitor dasatinib suppresses cytokine production by plasmacytoid dendritic cells by targeting endosomal transport of CpG DNA

    European Journal of Immunology

    Volume 43, Issue 1, January 2013, Pages: 93–103, Haruyuki Fujita, Toshio Kitawaki, Takayuki Sato, Takahiro Maeda, Shimeru Kamihira, Akifumi Takaori-Kondo and Norimitsu Kadowaki

    Version of Record online : 6 DEC 2012, DOI: 10.1002/eji.201242699

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    Hypoxia modulates the activity of a series of clinically approved tyrosine kinase inhibitors

    British Journal of Pharmacology

    Volume 171, Issue 1, January 2014, Pages: 224–236, M Ahmadi, Z Ahmadihosseini, S J Allison, S Begum, K Rockley, M Sadiq, S Chintamaneni, R Lokwani, N Hughes and R M Phillips

    Version of Record online : 10 DEC 2013, DOI: 10.1111/bph.12438