Search Results

There are 7972545 results for: content related to: Malignant Hypertension in Patients Treated With Vascular Endothelial Growth Factor Inhibitors

  1. An Evaluation of the Drug Interaction Potential of Pazopanib, an Oral Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, Using a Modified Cooperstown 5+1 Cocktail in Patients With Advanced Solid Tumors

    Clinical Pharmacology & Therapeutics

    Volume 88, Issue 5, November 2010, Pages: 652–659, B C Goh, N J Reddy, U B Dandamudi, K H Laubscher, T Peckham, J P Hodge, A B Suttle, T Arumugham, Y Xu, C-F Xu, J Lager, M M Dar and L D Lewis

    Version of Record online : 29 SEP 2010, DOI: 10.1038/clpt.2010.158

  2. You have free access to this content
    A novel multi-kinase inhibitor pazopanib suppresses growth of synovial sarcoma cells through inhibition of the PI3K-AKT pathway

    Journal of Orthopaedic Research

    Volume 30, Issue 9, September 2012, Pages: 1493–1498, Seiichi Hosaka, Keisuke Horiuchi, Masaki Yoda, Robert Nakayama, Takahide Tohmonda, Michiro Susa, Masaya Nakamura, Kazuhiro Chiba, Yoshiaki Toyama and Hideo Morioka

    Version of Record online : 22 FEB 2012, DOI: 10.1002/jor.22091

  3. A Phase I Study of the Pharmacokinetic and Safety Profiles of Oral Pazopanib With a High-Fat or Low-Fat Meal in Patients With Advanced Solid Tumors

    Clinical Pharmacology & Therapeutics

    Volume 88, Issue 6, December 2010, Pages: 818–823, E I Heath, E G Chiorean, C J Sweeney, J P Hodge, J J Lager, K Forman, L Malburg, T Arumugham, M M Dar, A B Suttle, S D Gainer and P LoRusso

    Version of Record online : 27 OCT 2010, DOI: 10.1038/clpt.2010.199

  4. You have full text access to this OnlineOpen article
    Pazopanib diminishes non-small cell lung cancer (NSCLC) growth and metastases in vivo

    Thoracic Cancer

    Volume 6, Issue 2, March 2015, Pages: 133–140, Honglin Zhao, Fan Yang, Wang Shen, Yuli Wang, Xuebing Li, Jiacong You and Qinghua Zhou

    Version of Record online : 2 MAR 2015, DOI: 10.1111/1759-7714.12138

  5. You have full text access to this OnlineOpen article
    The clinical outcome of pazopanib treatment in Japanese patients with relapsed soft tissue sarcoma: A Japanese Musculoskeletal Oncology Group (JMOG) study


    Volume 122, Issue 9, May 1, 2016, Pages: 1408–1416, Tomoki Nakamura, Akihiko Matsumine, Akira Kawai, Nobuhito Araki, Takahiro Goto, Tsukasa Yonemoto, Hideshi Sugiura, Yoshihiro Nishida, Hiroaki Hiraga, Kanya Honoki, Taketoshi Yasuda, Shogen Boku, Akihiro Sudo and Takafumi Ueda

    Version of Record online : 11 MAR 2016, DOI: 10.1002/cncr.29961

  6. You have full text access to this Open Access content
    Overview of fundamental study of pazopanib in cancer

    Thoracic Cancer

    Volume 5, Issue 6, November 2014, Pages: 487–493, Hong-Lin Zhao, Fan Yang, Xin Huang and Qing-Hua Zhou

    Version of Record online : 23 OCT 2014, DOI: 10.1111/1759-7714.12136

  7. Initial testing of the multitargeted kinase inhibitor pazopanib by the pediatric preclinical testing program

    Pediatric Blood & Cancer

    Volume 59, Issue 3, September 2012, Pages: 586–588, Stephen T. Keir, Christopher L. Morton, Jianrong Wu, Raushan T. Kurmasheva, Peter J. Houghton and Malcolm A. Smith

    Version of Record online : 20 DEC 2011, DOI: 10.1002/pbc.24016

  8. You have full text access to this OnlineOpen article
    Small molecules inhibiting the nuclear localization of YAP/TAZ for chemotherapeutics and chemosensitizers against breast cancers

    FEBS Open Bio

    Volume 5, Issue 1, January 01, 2015, Pages: 542–549, Yusuke Oku, Naoyuki Nishiya, Toshiya Shito, Reiichiro Yamamoto, Yasufumi Yamamoto, Chihiro Oyama and Yoshimasa Uehara

    Version of Record online : 22 JUN 2015, DOI: 10.1016/j.fob.2015.06.007

  9. Bayesian Methods for Pharmacokinetic/Pharmacodynamic Modeling of Pazopanib-Induced Increases in Blood Pressure and Transaminases

    The Journal of Clinical Pharmacology

    Volume 53, Issue 4, April 2013, Pages: 377–384, A. Benjamin Suttle, Paul de Souza and Thangam Arumugham

    Version of Record online : 4 FEB 2013, DOI: 10.1002/jcph.16

  10. You have free access to this content
    Recent advances in the treatment of advanced renal cell carcinoma: towards multidisciplinary personalized care

    BJU International

    Volume 110, Issue 9, November 2012, Pages: 1289–1300, Axel Bex, Martin Gore, Peter Mulders and Cora N. Sternberg

    Version of Record online : 30 MAR 2012, DOI: 10.1111/j.1464-410X.2012.11100.x

  11. Outcomes of unselected patients with metastatic clear-cell renal cell carcinoma treated with first-line pazopanib therapy followed by vascular endothelial growth factor receptor tyrosine kinase inhibitors or mammalian target of rapamycin inhibitors: a single institution experience

    BJU International

    Volume 118, Issue 2, August 2016, Pages: 264–271, Marc R. Matrana, Tharakeswara Bathala, Matthew T. Campbell, Cihan Duran, Aditya Shetty, Purnima Teegavarapu, Sarathi Kalra, Lianchun Xiao, Bradley Atkinson, Paul Corn, Eric Jonasch and Nizar M. Tannir

    Version of Record online : 13 DEC 2015, DOI: 10.1111/bju.13374

  12. You have free access to this content
    Quality-adjusted time without symptoms or toxicity analysis of pazopanib versus sunitinib in patients with renal cell carcinoma


    Volume 122, Issue 7, April 1, 2016, Pages: 1108–1115, Jennifer L. Beaumont, John M. Salsman, Jose Diaz, Keith C. Deen, Lauren McCann, Thomas Powles, Michelle D. Hackshaw, Robert J. Motzer and David Cella

    Version of Record online : 27 JAN 2016, DOI: 10.1002/cncr.29888

  13. You have free access to this content
    Health-related quality-of-life results from PALETTE: A randomized, double-blind, phase 3 trial of pazopanib versus placebo in patients with soft tissue sarcoma whose disease has progressed during or after prior chemotherapy—a European Organization for research and treatment of cancer soft tissue and bone sarcoma group global network study (EORTC 62072)


    Volume 121, Issue 17, September 1, 2015, Pages: 2933–2941, Corneel Coens, Winette T. A. van der Graaf, Jean-Yves Blay, Sant P. Chawla, Ian Judson, Roberta Sanfilippo, Stephanie C. Manson, Rachel A. Hodge, Sandrine Marreaud, Judith B. Prins, Iwona Lugowska, Saskia Litière and Andrew Bottomley

    Version of Record online : 29 MAY 2015, DOI: 10.1002/cncr.29426

  14. Preoperative Treatment With Pazopanib in a Case of Chemotherapy-Resistant Infantile Fibrosarcoma

    Pediatric Blood & Cancer

    Volume 63, Issue 2, February 2016, Pages: 348–351, Ryu Yanagisawa, Masahiko Noguchi, Kenya Fujita, Kazuo Sakashita, Kenji Sano, Yoshifumi Ogiso, Yoshihiko Katsuyama, Yoshiaki Kondo, Kazutoshi Komori, Ikuko Fujihara, Rei Kitamura, Takehiko Hiroma and Tomohiko Nakamura

    Version of Record online : 16 SEP 2015, DOI: 10.1002/pbc.25733

  15. Optimizing the dose in cancer patients treated with imatinib, sunitinib and pazopanib

    British Journal of Clinical Pharmacology

    Accepted manuscript online: 12 MAY 2017, N.A.G. Lankheet, I.M.E. Desar, S.F. Mulder, D.M. Burger, D.M. Kweekel, C.M.L. van Herpen, W.T.A. van der Graaf and N.P. van Erp

    DOI: 10.1111/bcp.13327

  16. You have full text access to this OnlineOpen article
    Preclinical Modeling of Tumor Growth and Angiogenesis Inhibition to Describe Pazopanib Clinical Effects in Renal Cell Carcinoma

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 4, Issue 11, November 2015, Pages: 660–668, A Ouerdani, H Struemper, AB Suttle, D Ouellet and B Ribba

    Version of Record online : 3 NOV 2015, DOI: 10.1002/psp4.12001

  17. Drug Absorption Interactions Between Oral Targeted Anticancer Agents and PPIs: Is pH-Dependent Solubility the Achilles Heel of Targeted Therapy?

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 2, August 2012, Pages: 203–213, N R Budha, A Frymoyer, G S Smelick, J Y Jin, M R Yago, M J Dresser, S N Holden, L Z Benet and J A Ware

    Version of Record online : 27 JUN 2012, DOI: 10.1038/clpt.2012.73

  18. You have free access to this content
    Patient-reported outcomes enhance understanding of the impact of pazopanib in soft tissue sarcoma


    Volume 121, Issue 17, September 1, 2015, Pages: 2868–2870, Carolyn Gotay

    Version of Record online : 29 MAY 2015, DOI: 10.1002/cncr.29429

  19. Reversible hair depigmentation in a Japanese female treated with pazopanib

    The Journal of Dermatology

    Volume 41, Issue 11, November 2014, Pages: 1021–1022, Eisuke Kobayashi, Taro Koyama, Kazuhiro Kobayashi, Nokitaka Setsu, Makoto Kawashima and Akira Kawai

    Version of Record online : 25 OCT 2014, DOI: 10.1111/1346-8138.12654

  20. You have free access to this content
    Pazopanib for patients with advanced soft tissue sarcomas in a real-life setting


    Volume 122, Issue 9, May 1, 2016, Pages: 1346–1348, Stefan Sleijfer

    Version of Record online : 11 MAR 2016, DOI: 10.1002/cncr.29963