Search Results

There are 10754 results for: content related to: Tofacitinib ( CP -690,550), an oral Janus kinase inhibitor, improves patient-reported outcomes in a phase 2b, randomized, double-blind, placebo-controlled study in patients with moderate-to-severe psoriasis

  1. You have full text access to this OnlineOpen article
    Effect of tofacitinib withdrawal and re-treatment on patient-reported outcomes: results from a Phase 3 study in patients with moderate to severe chronic plaque psoriasis

    Journal of the European Academy of Dermatology and Venereology

    Volume 31, Issue 2, February 2017, Pages: 323–332, C.E.M. Griffiths, R. Vender, H. Sofen, L. Kircik, H. Tan, S.T. Rottinghaus, M. Bachinsky, L. Mallbris and C. Mamolo

    Version of Record online : 7 SEP 2016, DOI: 10.1111/jdv.13808

  2. You have free access to this content
    2016 ACR/ARHP Annual Meeting Abstract Supplement

    Arthritis & Rheumatology

    Volume 68, Issue S10, October 2016, Pages: 1–4550,

    Version of Record online : 8 NOV 2016, DOI: 10.1002/art.39977

  3. You have free access to this content
    2015 ACR/ARHP Annual Meeting Abstract Supplement

    Arthritis & Rheumatology

    Volume 67, Issue S10, October 2015, Pages: 1–4046,

    Version of Record online : 5 NOV 2015, DOI: 10.1002/art.39448

  4. You have full text access to this OnlineOpen article
    Tofacitinib versus etanercept or placebo in patients with moderate to severe chronic plaque psoriasis: patient-reported outcomes from a Phase 3 study

    Journal of the European Academy of Dermatology and Venereology

    Volume 30, Issue 10, October 2016, Pages: 1753–1759, F. Valenzuela, C. Paul, L. Mallbris, H. Tan, J. Papacharalambous, H. Valdez and C. Mamolo

    Version of Record online : 7 JUN 2016, DOI: 10.1111/jdv.13702

  5. You have free access to this content
    A phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) versus placebo in combination with background methotrexate in patients with active rheumatoid arthritis and an inadequate response to methotrexate alone

    Arthritis & Rheumatism

    Volume 64, Issue 4, April 2012, Pages: 970–981, Joel M. Kremer, Stanley Cohen, Bethanie E. Wilkinson, Carol A. Connell, Jonathan L. French, Juan Gomez-Reino, David Gruben, Keith S. Kanik, Sriram Krishnaswami, Virginia Pascual-Ramos, Gene Wallenstein and Samuel H. Zwillich

    Version of Record online : 27 MAR 2012, DOI: 10.1002/art.33419

  6. You have free access to this content
    The JAK inhibitor tofacitinib regulates synovitis through inhibition of interferon-γ and interleukin-17 production by human CD4+ T cells

    Arthritis & Rheumatism

    Volume 64, Issue 6, June 2012, Pages: 1790–1798, Keisuke Maeshima, Kunihiro Yamaoka, Satoshi Kubo, Kazuhisa Nakano, Shigeru Iwata, Kazuyoshi Saito, Masanobu Ohishi, Hisaaki Miyahara, Shinya Tanaka, Koji Ishii, Hironobu Yoshimatsu and Yoshiya Tanaka

    Version of Record online : 25 MAY 2012, DOI: 10.1002/art.34329

  7. You have free access to this content
    Phase IIb dose-ranging study of the oral JAK inhibitor tofacitinib (CP-690,550) or adalimumab monotherapy versus placebo in patients with active rheumatoid arthritis with an inadequate response to disease-modifying antirheumatic drugs

    Arthritis & Rheumatism

    Volume 64, Issue 3, March 2012, Pages: 617–629, Roy Fleischmann, Maurizio Cutolo, Mark C. Genovese, Eun Bong Lee, Keith S. Kanik, Seth Sadis, Carol A. Connell, David Gruben, Sriram Krishnaswami, Gene Wallenstein, Bethanie E. Wilkinson and Samuel H. Zwillich

    Version of Record online : 28 FEB 2012, DOI: 10.1002/art.33383

  8. You have full text access to this OnlineOpen article
    Tofacitinib, an oral Janus kinase inhibitor, for the treatment of chronic plaque psoriasis: results from two randomized, placebo-controlled, phase III trials

    British Journal of Dermatology

    Volume 173, Issue 4, October 2015, Pages: 949–961, K.A. Papp, M.A. Menter, M. Abe, B. Elewski, S.R. Feldman, A.B. Gottlieb, R. Langley, T. Luger, D. Thaci, M. Buonanno, P. Gupta, J. Proulx, S. Lan, R. Wolk and for the OPT Pivotal 1 and OPT Pivotal 2 investigators

    Version of Record online : 29 OCT 2015, DOI: 10.1111/bjd.14018

  9. You have free access to this content
    Tofacitinib (CP-690,550) in patients with rheumatoid arthritis receiving methotrexate: Twelve-month data from a twenty-four–month phase III randomized radiographic study

    Arthritis & Rheumatism

    Volume 65, Issue 3, March 2013, Pages: 559–570, Désirée van der Heijde, Yoshiya Tanaka, Roy Fleischmann, Edward Keystone, Joel Kremer, Cristiano Zerbini, Mario H. Cardiel, Stanley Cohen, Peter Nash, Yeong-Wook Song, Dana Tegzová, Bradley T. Wyman, David Gruben, Birgitta Benda, Gene Wallenstein, Sriram Krishnaswami, Samuel H. Zwillich, John D. Bradley, Carol A. Connell and and the ORAL Scan Investigators

    Version of Record online : 25 FEB 2013, DOI: 10.1002/art.37816

  10. You have free access to this content
    Tofacitinib Facilitates the Expansion of Myeloid-Derived Suppressor Cells and Ameliorates Arthritis in SKG Mice

    Arthritis & Rheumatology

    Volume 67, Issue 4, April 2015, Pages: 893–902, Keisuke Nishimura, Jun Saegusa, Fumichika Matsuki, Kengo Akashi, Goichi Kageyama and Akio Morinobu

    Version of Record online : 27 MAR 2015, DOI: 10.1002/art.39007

  11. Efficacy of tofacitinib in treatment of alopecia universalis in two patients

    Journal of the European Academy of Dermatology and Venereology

    Volume 30, Issue 8, August 2016, Pages: 1373–1378, A.K. Gupta, J.L. Carviel and W. Abramovits

    Version of Record online : 15 JUN 2016, DOI: 10.1111/jdv.13598

  12. You have free access to this content
    Effects of Janus kinase inhibitor tofacitinib on circulating serum amyloid A and interleukin-6 during treatment for rheumatoid arthritis

    Clinical & Experimental Immunology

    Volume 175, Issue 2, February 2014, Pages: 208–214, K. Migita, Y. Izumi, Y. Jiuchi, H. Kozuru, C. Kawahara, M. Izumi, T. Sakai, M. Nakamura, S. Motokawa, T. Nakamura and A. Kawakami

    Version of Record online : 3 JAN 2014, DOI: 10.1111/cei.12234

  13. Tofacitinib withdrawal and retreatment in moderate-to-severe chronic plaque psoriasis: a randomized controlled trial

    British Journal of Dermatology

    Volume 172, Issue 5, May 2015, Pages: 1395–1406, R. Bissonnette, L. Iversen, H. Sofen, C.E.M. Griffiths, P. Foley, R. Romiti, M. Bachinsky, S.T. Rottinghaus, H. Tan, J. Proulx, H. Valdez, P. Gupta, L. Mallbris and R. Wolk

    Version of Record online : 2 APR 2015, DOI: 10.1111/bjd.13551

  14. Safety, tolerability, and pharmacokinetics of single oral doses of tofacitinib, a Janus kinase inhibitor, in healthy volunteers

    Clinical Pharmacology in Drug Development

    Volume 4, Issue 2, March/April 2015, Pages: 83–88, Sriram Krishnaswami, Mary Boy, Vincent Chow and Gary Chan

    Version of Record online : 5 DEC 2014, DOI: 10.1002/cpdd.171

  15. You have free access to this content
    Evaluation of the Effect of Tofacitinib Exposure on Outcomes in Kidney Transplant Patients

    American Journal of Transplantation

    Volume 15, Issue 6, June 2015, Pages: 1644–1653, F. Vincenti, H. T. Silva, S. Busque, P. J. O'Connell, G. Russ, K. Budde, A. Yoshida, M. A. Tortorici, M. Lamba, N. Lawendy, W. Wang and G. Chan

    Version of Record online : 3 FEB 2015, DOI: 10.1111/ajt.13181

  16. You have free access to this content
    Biologics or tofacitinib for rheumatoid arthritis in incomplete responders to methotrexate or other traditional disease-modifying anti-rheumatic drugs: a systematic review and network meta-analysis

    Overview of Reviews

    The Cochrane Library

    Jasvinder A Singh, Alomgir Hossain, Elizabeth Tanjong Ghogomu, Ahmed Kotb, Robin Christensen, Amy S Mudano, Lara J Maxwell, Nipam P Shah, Peter Tugwell and George A Wells

    Published Online : 13 MAY 2016, DOI: 10.1002/14651858.CD012183

  17. Biologic or tofacitinib monotherapy for rheumatoid arthritis in people with traditional disease-modifying anti-rheumatic drug (DMARD) failure: a Cochrane Systematic Review and network meta-analysis (NMA)

    Overview of Reviews

    The Cochrane Library

    Jasvinder A Singh, Alomgir Hossain, Elizabeth Tanjong Ghogomu, Amy S Mudano, Peter Tugwell and George A Wells

    Published Online : 17 NOV 2016, DOI: 10.1002/14651858.CD012437

  18. You have free access to this content
    ACR Meeting

    Arthritis & Rheumatism

    Volume 64, Issue S10, October 2012, Pages: S1–S1216,

    Version of Record online : 11 OCT 2012, DOI: 10.1002/art.37735

  19. You have free access to this content
    JAK inhibition with tofacitinib suppresses arthritic joint structural damage through decreased RANKL production

    Arthritis & Rheumatism

    Volume 64, Issue 11, November 2012, Pages: 3531–3542, Timothy P. LaBranche, Michael I. Jesson, Zaher A. Radi, Chad E. Storer, Julia A. Guzova, Sheri L. Bonar, Janice M. Thompson, Fernando A. Happa, Zachary S. Stewart, Yutian Zhan, Chris S. Bollinger, Prashant N. Bansal, Jeremy W. Wellen, Dean P. Wilkie, Steven A. Bailey, Peter T. Symanowicz, Martin Hegen, Richard D. Head, Nandini Kishore, Gabriel Mbalaviele and Debra M. Meyer

    Version of Record online : 27 OCT 2012, DOI: 10.1002/art.34649

  20. Small Molecules in the Treatment of Psoriasis

    Drug Development Research

    Volume 76, Issue 5, August 2015, Pages: 215–227, Tiago Torres and Paulo Filipe

    Version of Record online : 9 AUG 2015, DOI: 10.1002/ddr.21263