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There are 23617 results for: content related to: Pen-2 is dispensable for endoproteolysis of presenilin 1, and nicastrin-Aph subcomplex is important for both γ-secretase assembly and substrate recruitment

  1. Functional analysis and purification of a Pen-2 fusion protein for γ-secretase structural studies

    Journal of Neurochemistry

    Oliver Holmes, Swetha Paturi, Michael S. Wolfe and Dennis J. Selkoe

    Article first published online : 18 JUN 2014, DOI: 10.1111/jnc.12772

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    Important functional role of residue x of the presenilin GxGD protease active site motif for APP substrate cleavage specificity and substrate selectivity of γ-secretase

    Journal of Neurochemistry

    Volume 125, Issue 1, April 2013, Pages: 144–156, Benedikt Kretner, Akio Fukumori, Peer-Hendrik Kuhn, Blanca Isabel Pérez-Revuelta, Stefan F. Lichtenthaler, Christian Haass and Harald Steiner

    Article first published online : 15 JAN 2013, DOI: 10.1111/jnc.12124

  3. Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy

    Journal of Neurochemistry

    Volume 128, Issue 6, March 2014, Pages: 890–903, Arumugam R. Jayakumar, Xiao Y. Tong, Kevin M. Curtis, Roberto Ruiz-Cordero, Maria T. Abreu and Michael D. Norenberg

    Article first published online : 22 NOV 2013, DOI: 10.1111/jnc.12516

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    Role of endoplasmic reticulum stress in light-induced photoreceptor degeneration in mice

    Journal of Neurochemistry

    Volume 125, Issue 1, April 2013, Pages: 111–124, Tomohiro Nakanishi, Masamitsu Shimazawa, Sou Sugitani, Takashi Kudo, Shunsuke Imai, Yuta Inokuchi, Kazuhiro Tsuruma and Hideaki Hara

    Article first published online : 7 JAN 2013, DOI: 10.1111/jnc.12116

  5. Enhanced synthesis and release of dopamine in transgenic mice with gain-of-function α6* nAChRs

    Journal of Neurochemistry

    Volume 129, Issue 2, April 2014, Pages: 315–327, Yuexiang Wang, Jang-Won Lee, Gyeon Oh, Sharon R. Grady, J. Michael McIntosh, Darlene H. Brunzell, Jason R. Cannon and Ryan M. Drenan

    Article first published online : 13 DEC 2013, DOI: 10.1111/jnc.12616

  6. Relationships between serotonergic and cannabinoid system in depressive-like behavior: a PET study with [11C]-DASB

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 126–135, Aurelijus Burokas, Elena Martín-García, Javier Gutiérrez-Cuesta, Santiago Rojas, José Raúl Herance, Juan Domingo Gispert, Miquel-Ángel Serra and Rafael Maldonado

    Article first published online : 30 APR 2014, DOI: 10.1111/jnc.12716

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    The Neuroplastin adhesion molecules: key regulators of neuronal plasticity and synaptic function

    Journal of Neurochemistry

    Philip W. Beesley, Rodrigo Herrera-Molina, Karl-Heinz Smalla and Constanze Seidenbecher

    Article first published online : 14 AUG 2014, DOI: 10.1111/jnc.12816

  8. Specific subcellular changes in oxidative stress in prefrontal cortex from patients with bipolar disorder

    Journal of Neurochemistry

    Volume 127, Issue 4, November 2013, Pages: 552–561, Ana C. Andreazza, Jun-Feng Wang, Faraz Salmasi, Li Shao and Lionel T. Young

    Article first published online : 11 JUN 2013, DOI: 10.1111/jnc.12316

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    Diabetes in Friedreich Ataxia

    Journal of Neurochemistry

    Volume 126, Issue s1, August 2013, Pages: 94–102, Miriam Cnop, Hindrik Mulder and Mariana Igoillo-Esteve

    Article first published online : 17 JUL 2013, DOI: 10.1111/jnc.12216

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    Substrate determinants in the C99 juxtamembrane domains differentially affect γ–secretase cleavage specificity and modulator pharmacology

    Journal of Neurochemistry

    Volume 125, Issue 4, May 2013, Pages: 610–619, Solenne Ousson, Arman Saric, Aurelie Baguet, Christophe Losberger, Stephane Genoud, Francis Vilbois, Bruno Permanne, Ishrut Hussain and Dirk Beher

    Article first published online : 18 JAN 2013, DOI: 10.1111/jnc.12129

  11. Arrestin-dependent but G-protein coupled receptor kinase-independent uncoupling of D2-dopamine receptors

    Journal of Neurochemistry

    Volume 127, Issue 1, October 2013, Pages: 57–65, Jeremy Celver, Meenakshi Sharma, Vaidehi Thanawala, J. Christopher Octeau and Abraham Kovoor

    Article first published online : 29 JUL 2013, DOI: 10.1111/jnc.12359

  12. Presenilin 2 influences miR146 level and activity in microglia

    Journal of Neurochemistry

    Volume 127, Issue 5, December 2013, Pages: 592–599, Suman Jayadev, Amanda Case, Betty Alajajian, Alison J. Eastman, Thomas Möller and Gwenn A. Garden

    Article first published online : 30 SEP 2013, DOI: 10.1111/jnc.12400

  13. The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain

    Journal of Neurochemistry

    Volume 130, Issue 3, August 2014, Pages: 419–431, Caroline Kerridge, Nikolai D. Belyaev, Natalia N. Nalivaeva and Anthony J. Turner

    Article first published online : 12 MAR 2014, DOI: 10.1111/jnc.12680

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    Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease

    Journal of Neurochemistry

    Volume 129, Issue 5, June 2014, Pages: 756–769, Edgar Dawkins and David H. Small

    Article first published online : 7 MAR 2014, DOI: 10.1111/jnc.12675

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    Dynamin-2 in nervous system disorders

    Journal of Neurochemistry

    Volume 128, Issue 2, January 2014, Pages: 210–223, Arlek M. González-Jamett, Valentina Haro-Acuña, Fanny Momboisse, Pablo Caviedes, Jorge A. Bevilacqua and Ana M. Cárdenas

    Article first published online : 23 OCT 2013, DOI: 10.1111/jnc.12455

  16. The notch signaling pathway: its role in focal CNS demyelination and apotransferrin-induced remyelination

    Journal of Neurochemistry

    Volume 127, Issue 6, December 2013, Pages: 819–836, Evangelina Aparicio, Patricia Mathieu, Milagros Pereira Luppi, María Florencia Almeira Gubiani and Ana María Adamo

    Article first published online : 18 OCT 2013, DOI: 10.1111/jnc.12440

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    Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production

    Journal of Neurochemistry

    Volume 128, Issue 2, January 2014, Pages: 330–339, Marc Suárez-Calvet, Olivia Belbin, Marta Pera, Nahuai Badiola, Jordi Magrané, Cristina Guardia-Laguarta, Laia Muñoz, Martí Colom-Cadena, Jordi Clarimón and Alberto Lleó

    Article first published online : 24 OCT 2013, DOI: 10.1111/jnc.12466

  18. Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia

    Journal of Neurochemistry

    Volume 129, Issue 4, May 2014, Pages: 683–695, Ye Jin, Koichi Sato, Ayaka Tobo, Chihiro Mogi, Masayuki Tobo, Naoya Murata, Satoshi Ishii, Dong-Soon Im and Fumikazu Okajima

    Article first published online : 10 FEB 2014, DOI: 10.1111/jnc.12661

  19. Blocking the apolipoprotein E/Amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology

    Journal of Neurochemistry

    Volume 128, Issue 4, February 2014, Pages: 577–591, Shan Liu, Ariel Breitbart, Yanjie Sun, Pankaj D. Mehta, Allal Boutajangout, Henrieta Scholtzova and Thomas Wisniewski

    Article first published online : 6 NOV 2013, DOI: 10.1111/jnc.12484

  20. Brain region-specific changes in N-acylethanolamine contents with time of day

    Journal of Neurochemistry

    Volume 128, Issue 4, February 2014, Pages: 491–506, Elizabeth Sabens Liedhegner, Amy Sasman and Cecilia J. Hillard

    Article first published online : 13 NOV 2013, DOI: 10.1111/jnc.12495