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There are 14627 results for: content related to: Amelioration of cognitive deficits in plaque-bearing A lzheimer's disease model mice through selective reduction of nascent soluble A β 42 without affecting other A β pools

  1. You have free access to this content
    Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

    Journal of Neurochemistry

    Volume 126, Issue 3, August 2013, Pages: 305–311, Lei Gu and Zhefeng Guo

    Version of Record online : 12 MAR 2013, DOI: 10.1111/jnc.12202

  2. Identification of Physiological and Toxic Conformations in Aβ42 Aggregates

    ChemBioChem

    Volume 10, Issue 2, January 26, 2009, Pages: 287–295, Yuichi Masuda, Satoko Uemura, Ryutaro Ohashi, Azusa Nakanishi, K. Takegoshi, Takahiko Shimizu, Takuji Shirasawa and Kazuhiro Irie

    Version of Record online : 29 DEC 2008, DOI: 10.1002/cbic.200800411

  3. You have full text access to this OnlineOpen article
    Altered γ-secretase activity in mild cognitive impairment and Alzheimer's disease

    EMBO Molecular Medicine

    Volume 4, Issue 4, April 2012, Pages: 344–352, Nobuto Kakuda, Mikio Shoji, Hiroyuki Arai, Katsutoshi Furukawa, Takeshi Ikeuchi, Kohei Akazawa, Mako Takami, Hiroyuki Hatsuta, Shigeo Murayama, Yasuhiro Hashimoto, Masakazu Miyajima, Hajime Arai, Yu Nagashima, Haruyasu Yamaguchi, Ryozo Kuwano, Kazuhiro Nagaike, Yasuo Ihara and the Japanese Alzheimer's Disease Neuroimaging Initiative

    Version of Record online : 21 FEB 2012, DOI: 10.1002/emmm.201200214

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    Neuroprotective effects of donepezil against Aβ42-induced neuronal toxicity are mediated through not only enhancing PP2A activity but also regulating GSK-3β and nAChRs activity

    Journal of Neurochemistry

    Volume 127, Issue 4, November 2013, Pages: 562–574, Min-Young Noh, Seong H. Koh, Sung-Min Kim, Tangui Maurice, Sae-Kwang Ku and Seung H. Kim

    Version of Record online : 17 JUN 2013, DOI: 10.1111/jnc.12319

  5. β-Amyloid Therapeutic Strategies for Alzheimer's Disease

    Standard Article

    Burger's Medicinal Chemistry and Drug Discovery

    Bruno P. Imbimbo and Francesca Speroni

    Published Online : 14 OCT 2005, DOI: 10.1002/0471266949.bmc112

  6. Evidence that neurones accumulating amyloid can undergo lysis to form amyloid plaques in Alzheimer's disease

    Histopathology

    Volume 38, Issue 2, February 2001, Pages: 120–134, M R D'Andrea, R G Nagele, H-Y Wang, P A Peterson and D H S Lee

    Version of Record online : 21 DEC 2001, DOI: 10.1046/j.1365-2559.2001.01082.x

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    The turn formation at positions 22 and 23 in the 42-mer amyloid β peptide: The emerging role in the pathogenesis of Alzheimer's disease

    Geriatrics & Gerontology International

    Volume 10, Issue s1, July 2010, Pages: S169–S179, Kazuma Murakami, Yuichi Masuda, Takuji Shirasawa, Takahiko Shimizu and Kazuhiro Irie

    Version of Record online : 2 JUN 2010, DOI: 10.1111/j.1447-0594.2010.00598.x

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    The coexistence of an equal amount of Alzheimer's amyloid-β 40 and 42 forms structurally stable and toxic oligomers through a distinct pathway

    The FEBS Journal

    Volume 281, Issue 11, June 2014, Pages: 2674–2687, Yu-Jen Chang and Yun-Ru Chen

    Version of Record online : 6 MAY 2014, DOI: 10.1111/febs.12813

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    Inhibition of Alzheimer’s amyloid toxicity with a tricyclic pyrone molecule in vitro and in vivo

    Journal of Neurochemistry

    Volume 108, Issue 4, February 2009, Pages: 1097–1108, Hyun-Seok Hong, Sandeep Rana, Lydia Barrigan, Aibin Shi, Yi Zhang, Feimeng Zhou, Lee-Way Jin and Duy H. Hua

    Version of Record online : 25 DEC 2008, DOI: 10.1111/j.1471-4159.2008.05866.x

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    Cross-seeding effects of amyloid β-protein and α-synuclein

    Journal of Neurochemistry

    Volume 122, Issue 5, September 2012, Pages: 883–890, Kenjiro Ono, Ryoichi Takahashi, Tokuhei Ikeda and Masahito Yamada

    Version of Record online : 23 JUL 2012, DOI: 10.1111/j.1471-4159.2012.07847.x

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    Discovery of amyloid-beta aggregation inhibitors using an engineered assay for intracellular protein folding and solubility

    Protein Science

    Volume 18, Issue 2, February 2009, Pages: 277–286, Li Ling Lee, HyungHo Ha, Young-Tae Chang and Matthew P. DeLisa

    Version of Record online : 15 DEC 2008, DOI: 10.1002/pro.33

  12. β-amyloid peptide is internalized into chick retinal neurons and alters the distribution of myosin Vb

    Cytoskeleton

    Volume 69, Issue 3, March 2012, Pages: 166–178, Leandro T. Oliveira, Priscila A. Matos, David William Provance Jr., Fernando G. de Mello, Leonardo R. Andrade, Martha M. Sorenson and Verônica P. Salerno

    Version of Record online : 3 FEB 2012, DOI: 10.1002/cm.21007

  13. Extracellular amyloid beta 42 causes necrosis, inhibition of nuclear division, and mitotic disruption under both folate deficient and folate replete conditions as measured by the cytokinesis-block micronucleus cytome assay

    Environmental and Molecular Mutagenesis

    Volume 55, Issue 1, January 2014, Pages: 1–14, Sau Lai Lee, Philip Thomas and Michael Fenech

    Version of Record online : 28 AUG 2013, DOI: 10.1002/em.21811

  14. Distance Measurement between Tyr10 and Met35 in Amyloid β by Site-Directed Spin-Labeling ESR Spectroscopy: Implications for the Stronger Neurotoxicity of Aβ42 than Aβ40

    ChemBioChem

    Volume 8, Issue 18, December 17, 2007, Pages: 2308–2314, Kazuma Murakami, Hideyuki Hara, Yuichi Masuda, Hajime Ohigashi and Kazuhiro Irie

    Version of Record online : 19 NOV 2007, DOI: 10.1002/cbic.200700240

  15. Retro-Enantio N-Methylated Peptides as β-Amyloid Aggregation Inhibitors

    ChemMedChem

    Volume 4, Issue 9, September 4, 2009, Pages: 1488–1494, Dolors Grillo-Bosch, Natàlia Carulla, Montse Cruz, Laia Sánchez, Rosa Pujol-Pina, Sergio Madurga, Francesc Rabanal and Ernest Giralt

    Version of Record online : 9 JUL 2009, DOI: 10.1002/cmdc.200900191

  16. Inhibition of Aβ42 aggregation using peptides selected from combinatorial libraries

    Journal of Peptide Science

    Volume 15, Issue 8, August 2009, Pages: 499–503, Michael Baine, Daniel S. Georgie, Elelta Z. Shiferraw, Theresa P. T. Nguyen, Luiza A. Nogaj and David A. Moffet

    Version of Record online : 26 JUN 2009, DOI: 10.1002/psc.1150

  17. Amyloid β 38, 40, and 42 species in cerebrospinal fluid: More of the same?

    Annals of Neurology

    Volume 58, Issue 1, July 2005, Pages: 139–142, Niki S. Schoonenboom, Cees Mulder, Gerard J. Van Kamp, Sangita P. Mehta, Philip Scheltens, Marinus A. Blankenstein and Pankaj D. Mehta

    Version of Record online : 27 JUN 2005, DOI: 10.1002/ana.20508

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    Co-incorporation of Aβ40 and Aβ42 to form mixed pre-fibrillar aggregates

    European Journal of Biochemistry

    Volume 270, Issue 4, February 2003, Pages: 654–663, David Frost, Paul M Gorman, Christopher M. Yip and Avijit Chakrabartty

    Version of Record online : 24 JAN 2003, DOI: 10.1046/j.1432-1033.2003.03415.x

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    Modulation of β-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures

    Journal of Neurochemistry

    Volume 88, Issue 2, January 2004, Pages: 337–348, Laura Gasparini, Laura Rusconi, Huaxi Xu, Piero Del Soldato and Ennio Ongini

    Version of Record online : 23 DEC 2003, DOI: 10.1111/j.1471-4159.2004.02154.x

  20. High mobility group box protein-1 inhibits microglial Aβ clearance and enhances Aβ neurotoxicity

    Journal of Neuroscience Research

    Volume 78, Issue 6, 15 December 2004, Pages: 880–891, Kazuyuki Takata, Yoshihisa Kitamura, Daiju Tsuchiya, Toshiyuki Kawasaki, Takashi Taniguchi and Shun Shimohama

    Version of Record online : 21 OCT 2004, DOI: 10.1002/jnr.20340