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There are 31620 results for: content related to: Substrate determinants in the C99 juxtamembrane domains differentially affect γ–secretase cleavage specificity and modulator pharmacology

  1. SNJ-1945, a calpain inhibitor, protects SH-SY5Y cells against MPP+ and rotenone

    Journal of Neurochemistry

    Volume 130, Issue 2, July 2014, Pages: 280–290, Varduhi H. Knaryan, Supriti Samantaray, Sookyoung Park, Mitsuyoshi Azuma, Jun Inoue and Naren L. Banik

    Article first published online : 16 DEC 2013, DOI: 10.1111/jnc.12629

  2. Deletion of N-myc downstream-regulated gene 2 attenuates reactive astrogliosis and inflammatory response in a mouse model of cortical stab injury

    Journal of Neurochemistry

    Mika Takarada-Iemata, Dai Kezuka, Toshiaki Takeichi, Masahito Ikawa, Tsuyoshi Hattori, Yasuko Kitao and Osamu Hori

    Article first published online : 25 APR 2014, DOI: 10.1111/jnc.12729

  3. You have full text access to this OnlineOpen article
    A nicotinic acetylcholine receptor transmembrane point mutation (G275E) associated with resistance to spinosad in Frankliniella occidentalis

    Journal of Neurochemistry

    Volume 124, Issue 5, March 2013, Pages: 590–601, Alin M. Puinean, Stuart J. Lansdell, Toby Collins, Pablo Bielza and Neil S. Millar

    Article first published online : 13 JAN 2013, DOI: 10.1111/jnc.12029

  4. You have full text access to this OnlineOpen article
    Protein kinase Cβ is a modulator of the dopamine D2 autoreceptor-activated trafficking of the dopamine transporter

    Journal of Neurochemistry

    Volume 125, Issue 5, June 2013, Pages: 663–672, Rong Chen, Conor P. Daining, Haiguo Sun, Rheaclare Fraser, Stephanie L. Stokes, Michael Leitges and Margaret E. Gnegy

    Article first published online : 18 MAR 2013, DOI: 10.1111/jnc.12229

  5. TMEM106B p.T185S regulates TMEM106B protein levels: implications for frontotemporal dementia

    Journal of Neurochemistry

    Volume 126, Issue 6, September 2013, Pages: 781–791, Alexandra M. Nicholson, NiCole A. Finch, Aleksandra Wojtas, Matt C. Baker, Ralph B. Perkerson III, Monica Castanedes-Casey, Linda Rousseau, Luisa Benussi, Giuliano Binetti, Roberta Ghidoni, Ging-Yuek R. Hsiung, Ian R. Mackenzie, Elizabeth Finger, Bradley F. Boeve, Nilüfer Ertekin-Taner, Neill R. Graff-Radford, Dennis W. Dickson and Rosa Rademakers

    Article first published online : 1 JUL 2013, DOI: 10.1111/jnc.12329

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    Important functional role of residue x of the presenilin GxGD protease active site motif for APP substrate cleavage specificity and substrate selectivity of γ-secretase

    Journal of Neurochemistry

    Volume 125, Issue 1, April 2013, Pages: 144–156, Benedikt Kretner, Akio Fukumori, Peer-Hendrik Kuhn, Blanca Isabel Pérez-Revuelta, Stefan F. Lichtenthaler, Christian Haass and Harald Steiner

    Article first published online : 15 JAN 2013, DOI: 10.1111/jnc.12124

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    Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production

    Journal of Neurochemistry

    Volume 128, Issue 2, January 2014, Pages: 330–339, Marc Suárez-Calvet, Olivia Belbin, Marta Pera, Nahuai Badiola, Jordi Magrané, Cristina Guardia-Laguarta, Laia Muñoz, Martí Colom-Cadena, Jordi Clarimón and Alberto Lleó

    Article first published online : 24 OCT 2013, DOI: 10.1111/jnc.12466

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    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 4–28, Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong and Stefan F. Lichtenthaler

    Article first published online : 19 APR 2014, DOI: 10.1111/jnc.12715

  9. The neuroprotective activity of the amyloid precursor protein against traumatic brain injury is mediated via the heparin binding site in residues 96-110

    Journal of Neurochemistry

    Volume 128, Issue 1, January 2014, Pages: 196–204, Frances Corrigan, Emma Thornton, Laila C. Roisman, Anna V. Leonard, Robert Vink, Peter C. Blumbergs, Corinna van den Heuvel and Roberto Cappai

    Article first published online : 28 AUG 2013, DOI: 10.1111/jnc.12391

  10. The Aβ-clearance protein transthyretin, like neprilysin, is epigenetically regulated by the amyloid precursor protein intracellular domain

    Journal of Neurochemistry

    Caroline Kerridge, Nikolai D. Belyaev, Natalia N. Nalivaeva and Anthony J. Turner

    Article first published online : 12 MAR 2014, DOI: 10.1111/jnc.12680

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    Insights into the physiological function of the β-amyloid precursor protein: beyond Alzheimer's disease

    Journal of Neurochemistry

    Volume 129, Issue 5, June 2014, Pages: 756–769, Edgar Dawkins and David H. Small

    Article first published online : 7 MAR 2014, DOI: 10.1111/jnc.12675

  12. The notch signaling pathway: its role in focal CNS demyelination and apotransferrin-induced remyelination

    Journal of Neurochemistry

    Volume 127, Issue 6, December 2013, Pages: 819–836, Evangelina Aparicio, Patricia Mathieu, Milagros Pereira Luppi, María Florencia Almeira Gubiani and Ana María Adamo

    Article first published online : 18 OCT 2013, DOI: 10.1111/jnc.12440

  13. Inhibition of interleukin-1β production by extracellular acidification through the TDAG8/cAMP pathway in mouse microglia

    Journal of Neurochemistry

    Volume 129, Issue 4, May 2014, Pages: 683–695, Ye Jin, Koichi Sato, Ayaka Tobo, Chihiro Mogi, Masayuki Tobo, Naoya Murata, Satoshi Ishii, Dong-Soon Im and Fumikazu Okajima

    Article first published online : 10 FEB 2014, DOI: 10.1111/jnc.12661

  14. Blocking the apolipoprotein E/Amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology

    Journal of Neurochemistry

    Volume 128, Issue 4, February 2014, Pages: 577–591, Shan Liu, Ariel Breitbart, Yanjie Sun, Pankaj D. Mehta, Allal Boutajangout, Henrieta Scholtzova and Thomas Wisniewski

    Article first published online : 6 NOV 2013, DOI: 10.1111/jnc.12484

  15. Brain region-specific changes in N-acylethanolamine contents with time of day

    Journal of Neurochemistry

    Volume 128, Issue 4, February 2014, Pages: 491–506, Elizabeth Sabens Liedhegner, Amy Sasman and Cecilia J. Hillard

    Article first published online : 13 NOV 2013, DOI: 10.1111/jnc.12495

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    Cytosolic PINK1 escapes from mitochondria to promote dendritic outgrowth

    Journal of Neurochemistry

    Volume 128, Issue 6, March 2014, Pages: 787–789, Kim Tieu and Xu-Gang Xia

    Article first published online : 22 NOV 2013, DOI: 10.1111/jnc.12529

  17. AMP-activated protein kinase counteracts brain-derived neurotrophic factor-induced mammalian target of rapamycin complex 1 signaling in neurons

    Journal of Neurochemistry

    Volume 127, Issue 1, October 2013, Pages: 66–77, Yuta Ishizuka, Naomasa Kakiya, Lee A. Witters, Noriko Oshiro, Tomoaki Shirao, Hiroyuki Nawa and Nobuyuki Takei

    Article first published online : 29 JUL 2013, DOI: 10.1111/jnc.12362

  18. Molecular features of neural stem cells enable their enrichment using pharmacological inhibitors of survival-promoting kinases

    Journal of Neurochemistry

    Volume 128, Issue 3, February 2014, Pages: 376–390, Christine Y. Brazel, Abdulaziz A. Alaythan, Ryan J. Felling, Frances Calderon and Steven W. Levison

    Article first published online : 10 OCT 2013, DOI: 10.1111/jnc.12447

  19. Crosstalk between Dopamine D2 receptors and cannabinoid CB1 receptors regulates CNR1 promoter activity via ERK1/2 signaling

    Journal of Neurochemistry

    Volume 127, Issue 2, October 2013, Pages: 163–176, Yao-Chang Chiang, Yan-Ni Lo and Jin-Chung Chen

    Article first published online : 28 AUG 2013, DOI: 10.1111/jnc.12399

  20. Increased toll-like receptor 4 in cerebral endothelial cells contributes to the astrocyte swelling and brain edema in acute hepatic encephalopathy

    Journal of Neurochemistry

    Volume 128, Issue 6, March 2014, Pages: 890–903, Arumugam R. Jayakumar, Xiao Y. Tong, Kevin M. Curtis, Roberto Ruiz-Cordero, Maria T. Abreu and Michael D. Norenberg

    Article first published online : 22 NOV 2013, DOI: 10.1111/jnc.12516