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There are 12276 results for: content related to: Fishing for function – distinct roles of Bace1 and Bace2 in Zebrafish development

  1. You have free access to this content
    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 4–28, Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong and Stefan F. Lichtenthaler

    Version of Record online : 19 APR 2014, DOI: 10.1111/jnc.12715

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    Intracellular Itinerary of Internalised β-Secretase, BACE1, and Its Potential Impact on β-Amyloid Peptide Biogenesis


    Volume 14, Issue 9, September 2013, Pages: 997–1013, Pei Zhi Cheryl Chia, Wei Hong Toh, Robyn Sharples, Isabelle Gasnereau, Andrew F. Hill and Paul A. Gleeson

    Version of Record online : 8 JUL 2013, DOI: 10.1111/tra.12088

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    Loss of Bace2 in zebrafish affects melanocyte migration and is distinct from Bace1 knock out phenotypes

    Journal of Neurochemistry

    Volume 127, Issue 4, November 2013, Pages: 471–481, Frauke van Bebber, Alexander Hruscha, Michael Willem, Bettina Schmid and Christian Haass

    Version of Record online : 11 MAR 2013, DOI: 10.1111/jnc.12198

  4. You have full text access to this OnlineOpen article
    Neuronal β-amyloid generation is independent of lipid raft association of β-secretase BACE1: analysis with a palmitoylation-deficient mutant

    Brain and Behavior

    Volume 2, Issue 3, May 2012, Pages: 270–282, Kazumi Motoki, Hideaki Kume, Akiko Oda, Akira Tamaoka, Ai Hosaka, Fuyuki Kametani and Wataru Araki

    Version of Record online : 29 APR 2012, DOI: 10.1002/brb3.52

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    Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling

    Journal of Neurochemistry

    Volume 136, Issue 2, January 2016, Pages: 234–249, Xiangyou Hu, Qingyuan Fan, Hailong Hou and Riqiang Yan

    Version of Record online : 13 NOV 2015, DOI: 10.1111/jnc.13395

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    SCFFbx2-E3-ligase-mediated degradation of BACE1 attenuates Alzheimer’s disease amyloidosis and improves synaptic function

    Aging Cell

    Volume 9, Issue 6, December 2010, Pages: 1018–1031, Bing Gong, Fei Chen, Yong Pan, Isabel Arrieta-Cruz, Yukiko Yoshida, Vahram Haroutunian and Giulio M. Pasinetti

    Version of Record online : 29 OCT 2010, DOI: 10.1111/j.1474-9726.2010.00632.x

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    β-Site APP-cleaving enzyme 1 trafficking and Alzheimer’s disease pathogenesis

    Journal of Neurochemistry

    Volume 120, Issue 6, March 2012, Pages: 869–880, Jiangli Tan and Geneviève Evin

    Version of Record online : 23 JAN 2012, DOI: 10.1111/j.1471-4159.2011.07623.x

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    Size and sulfation are critical for the effect of heparin on APP processing and Aβ production

    Journal of Neurochemistry

    Volume 123, Issue 3, November 2012, Pages: 447–457, Hao Cui, Amos C. Hung, Craig Freeman, Christian Narkowicz, Glenn A. Jacobson and David H. Small

    Version of Record online : 21 SEP 2012, DOI: 10.1111/j.1471-4159.2012.07929.x

  9. miR-186 is decreased in aged brain and suppresses BACE1 expression

    Journal of Neurochemistry

    Volume 137, Issue 3, May 2016, Pages: 436–445, Jaekwang Kim, Hyejin Yoon, Dah-eun Chung, Jennifer L. Brown, Krystal C Belmonte and Jungsu Kim

    Version of Record online : 30 MAR 2016, DOI: 10.1111/jnc.13507

  10. Significance of transcytosis in Alzheimer's disease: BACE1 takes the scenic route to axons


    Volume 37, Issue 8, August 2015, Pages: 888–898, Virginie Buggia-Prévot and Gopal Thinakaran

    Version of Record online : 30 JUN 2015, DOI: 10.1002/bies.201500019

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    Identification of a cis-acting element involved in the regulation of BACE1 mRNA alternative splicing

    Journal of Neurochemistry

    Volume 109, Issue 4, May 2009, Pages: 1008–1016, Karen R. Mowrer and Michael S. Wolfe

    Version of Record online : 3 MAR 2009, DOI: 10.1111/j.1471-4159.2009.06026.x

  12. BACE1 Gene Expression and Protein Degradation

    Annals of the New York Academy of Sciences

    Volume 1035, Issue 1, December 2004, Pages: 49–67, WEIHUI ZHOU, HONG QING, YIGANG TONG and WEIHONG SONG

    Version of Record online : 12 JAN 2006, DOI: 10.1196/annals.1332.004

  13. You have full text access to this OnlineOpen article
    CHIP stabilizes amyloid precursor protein via proteasomal degradation and p53-mediated trans-repression of β-secretase

    Aging Cell

    Volume 14, Issue 4, August 2015, Pages: 595–604, Amir Kumar Singh and Uttam Pati

    Version of Record online : 13 MAR 2015, DOI: 10.1111/acel.12335

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    Camelid heavy chain only antibody fragment domain against β-site of amyloid precursor protein cleaving enzyme 1 inhibits β-secretase activity in vitro and in vivo

    The FEBS Journal

    Volume 282, Issue 18, September 2015, Pages: 3618–3631, Bram Dorresteijn, Maarten Rotman, Dorien Faber, Ruud Schravesande, Ernst Suidgeest, Louise van der Weerd, Silvère M. van der Maarel, Cornelis T. Verrips and Mohamed El Khattabi

    Version of Record online : 22 JUL 2015, DOI: 10.1111/febs.13367

  15. β-Secretase-1 elevation in aged monkey and Alzheimer’s disease human cerebral cortex occurs around the vasculature in partnership with multisystem axon terminal pathogenesis and β-amyloid accumulation

    European Journal of Neuroscience

    Volume 32, Issue 7, October 2010, Pages: 1223–1238, Yan Cai, Kun Xiong, Xue-Mei Zhang, Huaibin Cai, Xue-Gang Luo, Jia-Chun Feng, Richard W. Clough, Robert G. Struble, Peter R. Patrylo, Yaping Chu, Jeffrey H. Kordower and Xiao-Xin Yan

    Version of Record online : 18 AUG 2010, DOI: 10.1111/j.1460-9568.2010.07376.x

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    β-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins

    The FEBS Journal

    Volume 277, Issue 6, March 2010, Pages: 1503–1518, Carlo Sala Frigerio, Julia V. Fadeeva, Aedín M. Minogue, Martin Citron, Fred Van Leuven, Matthias Staufenbiel, Paolo Paganetti, Dennis J. Selkoe and Dominic M. Walsh

    Version of Record online : 15 FEB 2010, DOI: 10.1111/j.1742-4658.2010.07579.x

  17. ADAM10 and BACE1 are localized to synaptic vesicles

    Journal of Neurochemistry

    Volume 135, Issue 3, November 2015, Pages: 606–615, Jolanta L. Lundgren, Saheeb Ahmed, Sophia Schedin-Weiss, Gunnar K. Gouras, Bengt Winblad, Lars O. Tjernberg and Susanne Frykman

    Version of Record online : 17 SEP 2015, DOI: 10.1111/jnc.13287

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    Revisiting the peripheral sink hypothesis: inhibiting BACE1 activity in the periphery does not alter β-amyloid levels in the CNS

    Journal of Neurochemistry

    Volume 132, Issue 4, February 2015, Pages: 477–486, Biljana Georgievska, Susanne Gustavsson, Johan Lundkvist, Jan Neelissen, Susanna Eketjäll, Veronica Ramberg, Tjerk Bueters, Karin Agerman, Anders Juréus, Samuel Svensson, Stefan Berg, Johanna Fälting and Urban Lendahl

    Version of Record online : 18 SEP 2014, DOI: 10.1111/jnc.12937

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    Biochemical and kinetic characterization of BACE1: investigation into the putative species-specificity for β- and β′-cleavage sites by human and murine BACE1

    Journal of Neurochemistry

    Volume 91, Issue 6, December 2004, Pages: 1249–1259, Hsiu-Chiung Yang, Xiyun Chai, Marian Mosior, Wayne Kohn, Leonard N. Boggs, Jon A. Erickson, Don B. McClure, Wu-Kuang Yeh, Lianshen Zhang, Patricia Gonzalez-DeWhitt, John P. Mayer, Jose Alfredo Martin, Jingdan Hu, Shu-hui Chen, Ana Belen Bueno, Sheila P. Little, James R. McCarthy and Patrick C. May

    Version of Record online : 2 DEC 2004, DOI: 10.1111/j.1471-4159.2004.02764.x

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    Altered β-secretase enzyme kinetics and levels of both BACE1 and BACE2 in the Alzheimer's disease brain

    FEBS Letters

    Volume 580, Issue 28-29, December 11, 2006, Pages: 6550–6560, John H. Stockley, Rivka Ravid and Cora O’Neill

    Version of Record online : 13 NOV 2006, DOI: 10.1016/j.febslet.2006.10.076