Search Results

There are 10904 results for: content related to: Neuroprotective effects of donepezil against A β42-induced neuronal toxicity are mediated through not only enhancing PP 2 A activity but also regulating GSK -3β and n AChR s activity

  1. Membrane-bound tetramer and trimer Aβ oligomeric species correlate with toxicity towards cultured neurons

    Journal of Neurochemistry

    Volume 136, Issue 3, February 2016, Pages: 594–608, Metta K. Jana, Roberto Cappai, Chi L. L. Pham and Giuseppe D. Ciccotosto

    Article first published online : 19 JAN 2016, DOI: 10.1111/jnc.13443

  2. You have free access to this content
    Alzheimer's Aβ42 and Aβ40 peptides form interlaced amyloid fibrils

    Journal of Neurochemistry

    Volume 126, Issue 3, August 2013, Pages: 305–311, Lei Gu and Zhefeng Guo

    Article first published online : 12 MAR 2013, DOI: 10.1111/jnc.12202

  3. You have free access to this content
    Aβ40 modulates GABAA receptor α6 subunit expression and rat cerebellar granule neuron maturation through the ERK/mTOR pathway

    Journal of Neurochemistry

    Volume 128, Issue 3, February 2014, Pages: 350–362, Xiao-Qin Zhan, Jin-Jing Yao, Dong-Dong Liu, Qianqian Ma and Yan-Ai Mei

    Article first published online : 24 OCT 2013, DOI: 10.1111/jnc.12471

  4. You have free access to this content
    Blocking the apolipoprotein E/Amyloid β interaction in triple transgenic mice ameliorates Alzheimer's disease related amyloid β and tau pathology

    Journal of Neurochemistry

    Volume 128, Issue 4, February 2014, Pages: 577–591, Shan Liu, Ariel Breitbart, Yanjie Sun, Pankaj D. Mehta, Allal Boutajangout, Henrieta Scholtzova and Thomas Wisniewski

    Article first published online : 6 NOV 2013, DOI: 10.1111/jnc.12484

  5. You have free access to this content
    Autosomal-dominant Alzheimer's disease mutations at the same codon of amyloid precursor protein differentially alter Aβ production

    Journal of Neurochemistry

    Volume 128, Issue 2, January 2014, Pages: 330–339, Marc Suárez-Calvet, Olivia Belbin, Marta Pera, Nahuai Badiola, Jordi Magrané, Cristina Guardia-Laguarta, Laia Muñoz, Martí Colom-Cadena, Jordi Clarimón and Alberto Lleó

    Article first published online : 24 OCT 2013, DOI: 10.1111/jnc.12466

  6. Inhibiting amyloid β-protein assembly: Size–activity relationships among grape seed-derived polyphenols

    Journal of Neurochemistry

    Volume 135, Issue 2, October 2015, Pages: 416–430, Eric Y. Hayden, Ghiam Yamin, Shiela Beroukhim, Benson Chen, Mikhail Kibalchenko, Lin Jiang, Lap Ho, Jun Wang, Giulio M. Pasinetti and David B. Teplow

    Article first published online : 2 SEP 2015, DOI: 10.1111/jnc.13270

  7. You have free access to this content
    Amelioration of cognitive deficits in plaque-bearing Alzheimer's disease model mice through selective reduction of nascent soluble Aβ42 without affecting other Aβ pools

    Journal of Neurochemistry

    Volume 125, Issue 3, May 2013, Pages: 465–472, Yasuyuki Mitani, Junko Yarimizu, Hiroki Akashiba, Yoshitsugu Shitaka, Keni Ni and Nobuya Matsuoka

    Article first published online : 8 JAN 2013, DOI: 10.1111/jnc.12125

  8. You have free access to this content
    Substrate determinants in the C99 juxtamembrane domains differentially affect γ–secretase cleavage specificity and modulator pharmacology

    Journal of Neurochemistry

    Volume 125, Issue 4, May 2013, Pages: 610–619, Solenne Ousson, Arman Saric, Aurelie Baguet, Christophe Losberger, Stephane Genoud, Francis Vilbois, Bruno Permanne, Ishrut Hussain and Dirk Beher

    Article first published online : 18 JAN 2013, DOI: 10.1111/jnc.12129

  9. You have full text access to this OnlineOpen article
    APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective

    Journal of Neurochemistry

    Volume 133, Issue 4, May 2015, Pages: 465–488, Leon M. Tai, Shivesh Ghura, Kevin P. Koster, Vaiva Liakaite, Mark Maienschein-Cline, Pinal Kanabar, Nicole Collins, Manel Ben-Aissa, Arden Zhengdeng Lei, Neil Bahroos, Stefan J. Green, Bill Hendrickson, Linda J. Van Eldik and Mary Jo LaDu

    Article first published online : 18 MAR 2015, DOI: 10.1111/jnc.13072

  10. You have free access to this content
    A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity

    Journal of Neurochemistry

    Volume 130, Issue 2, July 2014, Pages: 291–300, Yuichi Hashimoto and Masaaki Matsuoka

    Article first published online : 9 APR 2014, DOI: 10.1111/jnc.12717

  11. You have free access to this content
    Arctic mutant Aβ40 aggregates on α7 nicotinic acetylcholine receptors and inhibits their functions

    Journal of Neurochemistry

    Volume 131, Issue 5, December 2014, Pages: 667–674, Ye Ju, Toru Asahi and Naoya Sawamura

    Article first published online : 14 AUG 2014, DOI: 10.1111/jnc.12837

  12. You have free access to this content
    Neurological dysfunctions associated with altered BACE1-dependent Neuregulin-1 signaling

    Journal of Neurochemistry

    Volume 136, Issue 2, January 2016, Pages: 234–249, Xiangyou Hu, Qingyuan Fan, Hailong Hou and Riqiang Yan

    Article first published online : 13 NOV 2015, DOI: 10.1111/jnc.13395

  13. You have free access to this content
    Signaling pathways regulating neuron–glia interaction and their implications in Alzheimer's disease

    Journal of Neurochemistry

    Volume 136, Issue 3, February 2016, Pages: 475–491, Hong Lian and Hui Zheng

    Article first published online : 30 NOV 2015, DOI: 10.1111/jnc.13424

  14. Identification of new Presenilin-1 phosphosites: implication for γ-secretase activity and Aβ production

    Journal of Neurochemistry

    Volume 133, Issue 3, May 2015, Pages: 409–421, Alexandre Matz, Blanka Halamoda-Kenzaoui, Romain Hamelin, Sebastien Mosser, Jean-René Alattia, Mitko Dimitrov, Marc Moniatte and Patrick C. Fraering

    Article first published online : 24 FEB 2015, DOI: 10.1111/jnc.12996

  15. You have free access to this content
    Dietary energy substrates reverse early neuronal hyperactivity in a mouse model of Alzheimer's disease

    Journal of Neurochemistry

    Volume 125, Issue 1, April 2013, Pages: 157–171, Misha Zilberter, Anton Ivanov, Sofya Ziyatdinova, Marat Mukhtarov, Anton Malkov, Alan Alpár, Giuseppe Tortoriello, Catherine H. Botting, Lívia Fülöp, Alex A. Osypov, Asla Pitkänen, Heikki Tanila, Tibor Harkany and Yuri Zilberter

    Article first published online : 10 JAN 2013, DOI: 10.1111/jnc.12127

  16. You have free access to this content
    Systemic vaccination with anti-oligomeric monoclonal antibodies improves cognitive function by reducing Aβ deposition and tau pathology in 3xTg-AD mice

    Journal of Neurochemistry

    Volume 126, Issue 4, August 2013, Pages: 473–482, Suhail Rasool, Hilda Martinez-Coria, Jessica W. Wu, Frank LaFerla and Charles G. Glabe

    Article first published online : 16 JUN 2013, DOI: 10.1111/jnc.12305

  17. You have free access to this content
    Function, therapeutic potential and cell biology of BACE proteases: current status and future prospects

    Journal of Neurochemistry

    Volume 130, Issue 1, July 2014, Pages: 4–28, Robert Vassar, Peer-Hendrik Kuhn, Christian Haass, Matthew E. Kennedy, Lawrence Rajendran, Philip C. Wong and Stefan F. Lichtenthaler

    Article first published online : 19 APR 2014, DOI: 10.1111/jnc.12715

  18. A novel DYRK1A (Dual specificity tyrosine phosphorylation-regulated kinase 1A) inhibitor for the treatment of Alzheimer's disease: effect on Tau and amyloid pathologies in vitro

    Journal of Neurochemistry

    Volume 133, Issue 3, May 2015, Pages: 440–451, Séverine Coutadeur, Hélène Benyamine, Laurence Delalonde, Catherine de Oliveira, Bertrand Leblond, Alicia Foucourt, Thierry Besson, Anne-Sophie Casagrande, Thierry Taverne, Angélique Girard, Matthew P. Pando and Laurent Désiré

    Article first published online : 26 JAN 2015, DOI: 10.1111/jnc.13018

  19. You have free access to this content
    Current approaches to enhance glutamate transporter function and expression

    Journal of Neurochemistry

    Volume 134, Issue 6, September 2015, Pages: 982–1007, Andréia C. K. Fontana

    Article first published online : 14 AUG 2015, DOI: 10.1111/jnc.13200

  20. You have free access to this content
    Amyloid beta1–42 (Aβ42) up-regulates the expression of sortilin via the p75NTR/RhoA signaling pathway

    Journal of Neurochemistry

    Volume 127, Issue 2, October 2013, Pages: 152–162, Khalil Saadipour, Miao Yang, Yoon Lim, Kristen Georgiou, Ying Sun, Damien Keating, Jia Liu, Ye-Ran Wang, Wei-ping Gai, Jin-hua Zhong, Yan-Jiang Wang and Xin-Fu Zhou

    Article first published online : 22 AUG 2013, DOI: 10.1111/jnc.12383