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There are 2127 results for: content related to: Hypoxia causes autophagic stress and derangement of metabolic adaptation in a cell model of amyotrophic lateral sclerosis

  1. Cell culture models to investigate the selective vulnerability of motoneuronal mitochondria to familial ALS-linked G93ASOD1

    European Journal of Neuroscience

    Volume 24, Issue 2, July 2006, Pages: 387–399, Andrea Raimondi, Alessandra Mangolini, Milena Rizzardini, Silvia Tartari, Silvia Massari, Caterina Bendotti, Maura Francolini, Nica Borgese, Lavinia Cantoni and Grazia Pietrini

    Article first published online : 18 JUL 2006, DOI: 10.1111/j.1460-9568.2006.04922.x

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    Increased mitochondrial antioxidative activity or decreased oxygen free radical propagation prevent mutant SOD1-mediated motor neuron cell death and increase amyotrophic lateral sclerosis-like transgenic mouse survival

    Journal of Neurochemistry

    Volume 80, Issue 3, February 2002, Pages: 488–500, Rugao Liu, Baolin Li, Shawn W. Flanagan, Larry W. Oberley, David Gozal and Mengsheng Qiu

    Article first published online : 21 JAN 2002, DOI: 10.1046/j.0022-3042.2001.00720.x

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    Adaptation to G93Asuperoxide dismutase 1 in a motor neuron cell line model of amyotrophic lateral sclerosis

    The FEBS Journal

    Volume 276, Issue 10, May 2009, Pages: 2861–2874, Silvia Tartari, Giuseppina D’Alessandro, Elisabetta Babetto, Milena Rizzardini, Laura Conforti and Lavinia Cantoni

    Article first published online : 14 APR 2009, DOI: 10.1111/j.1742-4658.2009.07010.x

  4. Altered astrocytic response to activation in SOD1G93A mice and its implications on amyotrophic lateral sclerosis pathogenesis

    Glia

    Volume 61, Issue 3, March 2013, Pages: 312–326, Chen Benkler, Tali Ben-Zur, Yael Barhum and Daniel Offen

    Article first published online : 22 DEC 2012, DOI: 10.1002/glia.22428

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    Inactivation of cytochrome c oxidase by mutant SOD1s in mouse motoneuronal NSC-34 cells is independent from copper availability but is because of nitric oxide

    Journal of Neurochemistry

    Volume 112, Issue 1, January 2010, Pages: 183–192, Mario Arciello, Concetta Rosa Capo, Mauro Cozzolino, Alberto Ferri, Monica Nencini, Maria Teresa Carrì and Luisa Rossi

    Article first published online : 20 OCT 2009, DOI: 10.1111/j.1471-4159.2009.06441.x

  6. Extracellular aggregated Cu/Zn superoxide dismutase activates microglia to give a cytotoxic phenotype

    Glia

    Volume 61, Issue 3, March 2013, Pages: 409–419, Kate Roberts, Rafaa Zeineddine, Lisa Corcoran, Wen Li, Iain L. Campbell and Justin J. Yerbury

    Article first published online : 22 DEC 2012, DOI: 10.1002/glia.22444

  7. Antisense peptide nucleic acid targeting GluR3 delays disease onset and progression in the SOD1 G93A mouse model of familial ALS

    Journal of Neuroscience Research

    Volume 77, Issue 4, 15 August 2004, Pages: 573–582, Alan Rembach, Bradley J. Turner, Stephen Bruce, Irwin K. Cheah, Rachel L. Scott, Elizabeth C. Lopes, Chrissandra J. Zagami, Philip M. Beart, Nam S. Cheung, Steven J. Langford and Surindar S. Cheema

    Article first published online : 16 JUN 2004, DOI: 10.1002/jnr.20191

  8. Role of GSK-3β activity in motor neuronal cell death induced by G93A or A4V mutant hSOD1 gene

    European Journal of Neuroscience

    Volume 22, Issue 2, July 2005, Pages: 301–309, Seong-Ho Koh, Young-Bae Lee, Kyung S. Kim, Hyun-Jung Kim, Manho Kim, Young Joo Lee, Juhan Kim, Kwang Woo Lee and Seung Hyun Kim

    Article first published online : 21 JUL 2005, DOI: 10.1111/j.1460-9568.2005.04191.x

  9. A Chemical Chaperone-Based Drug Candidate is Effective in a Mouse Model of Amyotrophic Lateral Sclerosis (ALS)

    ChemMedChem

    Volume 10, Issue 5, May 2015, Pages: 850–861, Tamar Getter, Ilana Zaks, Yael Barhum, Dr. Tali Ben-Zur, Dr. Sebastian Böselt, Dr. Simpson Gregoire, Olga Viskind, Tom Shani, Dr. Hugo Gottlieb, Omer Green, Moran Shubely, Prof. Hanoch Senderowitz, Dr. Adrian Israelson, Prof. Inchan Kwon, Prof. Susanne Petri, Prof. Daniel Offen and Dr. Arie Gruzman

    Article first published online : 13 MAR 2015, DOI: 10.1002/cmdc.201500045

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    Transglutaminase 2 accelerates neuroinflammation in amyotrophic lateral sclerosis through interaction with misfolded superoxide dismutase 1

    Journal of Neurochemistry

    Volume 128, Issue 3, February 2014, Pages: 403–418, Miki Oono, Ayako Okado-Matsumoto, Akemi Shodai, Akemi Ido, Yasuyuki Ohta, Koji Abe, Takashi Ayaki, Hidefumi Ito, Ryosuke Takahashi, Naoyuki Taniguchi and Makoto Urushitani

    Article first published online : 30 SEP 2013, DOI: 10.1111/jnc.12441

  11. Opposing effects of low and high-dose clozapine on survival of transgenic amyotrophic lateral sclerosis mice

    Journal of Neuroscience Research

    Volume 74, Issue 4, 15 November 2003, Pages: 605–613, B.J. Turner, A. Rembach, R. Spark, E.C. Lopes and S.S. Cheema

    Article first published online : 25 SEP 2003, DOI: 10.1002/jnr.10796

  12. N-acetyl-l-tryptophan, but not N-acetyl-d-tryptophan, rescues neuronal cell death in models of amyotrophic lateral sclerosis

    Journal of Neurochemistry

    Volume 134, Issue 5, September 2015, Pages: 956–968, Ana C. Sirianni, Jiying Jiang, Jiang Zeng, Lilly L. Mao, Shuanhu Zhou, Peter Sugarbaker, Xinmu Zhang, Wei Li, Robert M. Friedlander and Xin Wang

    Article first published online : 14 JUL 2015, DOI: 10.1111/jnc.13190

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    Mitochondrial dysfunction in amyotrophic lateral sclerosis – a valid pharmacological target?

    British Journal of Pharmacology

    Volume 171, Issue 8, April 2014, Pages: 2191–2205, H Muyderman and T Chen

    Article first published online : 28 MAR 2014, DOI: 10.1111/bph.12476

  14. Characterization and use of the NSC-34 cell line for study of neurotrophin receptor trafficking

    Journal of Neuroscience Research

    Volume 86, Issue 3, 15 February 2008, Pages: 553–565, Dusan Matusica, Matthew P. Fenech, Mary-Louise Rogers and Robert A. Rush

    Article first published online : 26 SEP 2007, DOI: 10.1002/jnr.21507

  15. You have full text access to this OnlineOpen article
    Suppressed autophagy flux in skeletal muscle of an amyotrophic lateral sclerosis mouse model during disease progression

    Physiological Reports

    Volume 3, Issue 1, January 2015, Yajuan Xiao, Changling Ma, Jianxun Yi, Shaoping Wu, Guo Luo, Xiulong Xu, Pei-Hui Lin, Jun Sun and Jingsong Zhou

    Article first published online : 19 JAN 2015, DOI: 10.14814/phy2.12271

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    Intracerebroventricular infusion of monoclonal antibody or its derived Fab fragment against misfolded forms of SOD1 mutant delays mortality in a mouse model of ALS

    Journal of Neurochemistry

    Volume 113, Issue 5, June 2010, Pages: 1188–1199, Francois Gros-Louis, Geneviève Soucy, Roxanne Larivière and Jean-Pierre Julien

    Article first published online : 14 MAR 2010, DOI: 10.1111/j.1471-4159.2010.06683.x

  17. Effect of ubiquitin expression on neuropathogenesis in a mouse model of familial amyotrophic lateral sclerosis

    Neuropathology and Applied Neurobiology

    Volume 31, Issue 1, February 2005, Pages: 20–33, C. A. Gilchrist, D. A. Gray, A. Stieber, N. K. Gonatas and R. R. Kopito

    Article first published online : 11 NOV 2004, DOI: 10.1111/j.1365-2990.2004.00604.x

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    Mutant SOD1 inhibits ER-Golgi transport in amyotrophic lateral sclerosis

    Journal of Neurochemistry

    Volume 129, Issue 1, April 2014, Pages: 190–204, Julie D. Atkin, Manal A. Farg, Kai Ying Soo, Adam K. Walker, Mark Halloran, Bradley J. Turner, Phillip Nagley and Malcolm K. Horne

    Article first published online : 13 NOV 2013, DOI: 10.1111/jnc.12493

  19. MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models

    Muscle & Nerve

    Volume 38, Issue 3, September 2008, Pages: 1173–1183, Florian L. Muller, Yuhong Liu, Amanda Jernigan, David Borchelt, Arlan Richardson and Holly Van Remmen

    Article first published online : 21 AUG 2008, DOI: 10.1002/mus.21049

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    S-nitrosylated protein disulfide isomerase contributes to mutant SOD1 aggregates in amyotrophic lateral sclerosis

    Journal of Neurochemistry

    Volume 124, Issue 1, January 2013, Pages: 45–58, Xueping Chen, Xiaosha Zhang, Chen Li, Teng Guan, Huifang Shang, Liying Cui, Xin-Min Li and Jiming Kong

    Article first published online : 1 NOV 2012, DOI: 10.1111/jnc.12046