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There are 23698 results for: content related to: Hepatic and intestinal CYP 3 A expression and activity in broilers

  1. In vitro metabolism of testosterone in the horse liver and involvement of equine CYPs 3A89, 3A94 and 3A95

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 37, Issue 4, August 2014, Pages: 338–347, A. Schmitz, J. Zielinski, B. Dick and M. Mevissen

    Article first published online : 31 JAN 2014, DOI: 10.1111/jvp.12106

  2. The genes of all seven CYP3A isoenzymes identified in the equine genome are expressed in the airways of horses

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 36, Issue 4, August 2013, Pages: 370–375, E. Tydén, M. Löfgren, M. Hakhverdyan, H. Tjälve and P. Larsson

    Article first published online : 12 SEP 2012, DOI: 10.1111/jvp.12012

  3. Identification and Phenotype Characterization of Two CYP3A Haplotypes Causing Different Enzymatic Capacity in Fetal Livers

    Clinical Pharmacology & Therapeutics

    Volume 77, Issue 4, April 2005, Pages: 259–270, Cristina Rodríguez-Antona, Mary Jande, Anders Rane and Magnus Ingelman-Sundberg

    Article first published online : 2 APR 2005, DOI: 10.1016/j.clpt.2004.11.003

  4. Influence of CYP3A5 Genotype on the Pharmacokinetics and Pharmacodynamics of the Cytochrome P4503A Probes Alfentanil and Midazolam

    Clinical Pharmacology & Therapeutics

    Volume 82, Issue 4, October 2007, Pages: 410–426, E D Kharasch, A Walker, N Isoherranen, C Hoffer, P Sheffels, K Thummel, D Whittington and D Ensign

    Article first published online : 6 JUN 2007, DOI: 10.1038/sj.clpt.6100237

  5. Determination of a quantitative relationship between hepatic CYP3A5*1/*3 and CYP3A4 expression for use in the prediction of metabolic clearance in virtual populations

    Biopharmaceutics & Drug Disposition

    Volume 31, Issue 8-9, November - December 2010, Pages: 516–532, Z. E. Barter, H. F. Perrett, K. Rowland Yeo, D. Allorge, M. S. Lennard and A. Rostami-Hodjegan

    Article first published online : 23 NOV 2010, DOI: 10.1002/bdd.732

  6. Effect of CYP3A5*3 genotype on the pharmacokinetics and pharmacodynamics of amlodipine in healthy Korean subjects

    Clinical Pharmacology & Therapeutics

    Volume 80, Issue 6, December 2006, Pages: 646–656, Kyoung-Ah Kim, Pil-Whan Park, Ock-Je Lee, Sang-Hyun Choi, Bon Hong Min, Kyung-Ho Shin, Boe-Gwun Chun, Jae-Gook Shin and Ji-Young Park

    Article first published online : 15 DEC 2006, DOI: 10.1016/j.clpt.2006.09.009

  7. CYP3A5 and CYP3A4 but not MDR1 Single-nucleotide Polymorphisms Determine Long-term Tacrolimus Disposition and Drug-related Nephrotoxicity in Renal Recipients

    Clinical Pharmacology & Therapeutics

    Volume 82, Issue 6, December 2007, Pages: 711–725, D R J Kuypers, H de Jonge, M Naesens, E Lerut, K Verbeke and Y Vanrenterghem

    Article first published online : 9 MAY 2007, DOI: 10.1038/sj.clpt.6100216

  8. Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus

    Clinical Pharmacology & Therapeutics

    Volume 74, Issue 3, September 2003, Pages: 245–254, Dennis A. Hesselink, Ron H. N. van Schaik, Ilse P. van der Heiden, Marloes van der Werf, Peter J. H. Smak Gregoor, Jan Lindemans, Willem Weimar and Teun van Gelder

    Article first published online : 17 SEP 2003, DOI: 10.1016/S0009-9236(03)00168-1

  9. You have full text access to this OnlineOpen article
    Effect of CYP3A4*22, CYP3A5*3, and CYP3A Combined Genotypes on Cyclosporine, Everolimus, and Tacrolimus Pharmacokinetics in Renal Transplantation

    CPT: Pharmacometrics & Systems Pharmacology

    Volume 3, Issue 2, February 2014, Pages: 1–12, DJAR Moes, JJ Swen, J den Hartigh, T van der Straaten, JJ Homan van der Heide, JS Sanders, FJ Bemelman, JW de Fijter and HJ Guchelaar

    Article first published online : 12 FEB 2014, DOI: 10.1038/psp.2013.78

  10. Kidney Transplant Recipients Carrying the CYP3A4*22 Allelic Variant Have Reduced Tacrolimus Clearance and Often Reach Supratherapeutic Tacrolimus Concentrations

    American Journal of Transplantation

    Volume 15, Issue 3, March 2015, Pages: 800–805, N. Pallet, A.-S. Jannot, M. El Bahri, I. Etienne, M. Buchler, B. H. de Ligny, G. Choukroun, C. Colosio, A. Thierry, C. Vigneau, B. Moulin, Y. Le Meur, A.-E. Heng, J.-F. Subra, C. Legendre, P. Beaune, C. Alberti, M. A. Loriot and E. Thervet

    Article first published online : 14 JAN 2015, DOI: 10.1111/ajt.13059

  11. The CYP3A4*18 Genotype in the Cytochrome P450 3A4 Gene, a Rapid Metabolizer of Sex Steroids, Is Associated With Low Bone Mineral Density

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 3, March 2009, Pages: 312–318, YS Kang, SY Park, CH Yim, HS Kwak, P Gajendrarao, N Krishnamoorthy, S-C Yun, KW Lee and KO Han

    Article first published online : 19 NOV 2008, DOI: 10.1038/clpt.2008.215

  12. You have free access to this content
    Ontogeny of CYP3A and P-Glycoprotein in the Liver and the Small Intestine of the Göttingen Minipig: An Immunohistochemical Evaluation

    Basic & Clinical Pharmacology & Toxicology

    Volume 114, Issue 5, May 2014, Pages: 387–394, Els Van Peer, Evy Verbueken, Moayad Saad, Christophe Casteleyn, Chris Van Ginneken and Steven Van Cruchten

    Article first published online : 13 DEC 2013, DOI: 10.1111/bcpt.12173

  13. You have free access to this content
    Clinical implementation of pharmacogenetics in kidney transplantation: calcineurin inhibitors in the starting blocks

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 715–728, Laure Elens, Rachida Bouamar, Nauras Shuker, Dennis A. Hesselink, Teun van Gelder and Ron H. N. van Schaik

    Article first published online : 20 MAR 2014, DOI: 10.1111/bcp.12253

  14. DDI Risk Assessment and Evaluation in Pharmaceutical Development: Interfacing Drug Metabolism and Clinical Pharmacology

    Standard Article

    Encyclopedia of Drug Metabolism and Interactions

    Karthik Venkatakrishnan

    Published Online : 15 OCT 2012, DOI: 10.1002/9780470921920.edm118

  15. Genotype-phenotype Associations of Cytochrome P450 3A4 and 3A5 Polymorphism with Midazolam Clearance in Vivo

    Clinical Pharmacology & Therapeutics

    Volume 77, Issue 5, May 2005, Pages: 373–387, Ping He, Michael H. Court, David J. Greenblatt and Lisa L. von Moltke

    Article first published online : 16 MAY 2005, DOI: 10.1016/j.clpt.2004.11.112

  16. Differential gene expression of CYP3A isoforms in equine liver and intestines

    Journal of Veterinary Pharmacology and Therapeutics

    Volume 35, Issue 6, December 2012, Pages: 588–595, E. TYDÉN, M. LÖFGREN, S. PEGOLO, F. CAPOLONGO, H. TJÄLVE and P. LARSSON

    Article first published online : 29 JAN 2012, DOI: 10.1111/j.1365-2885.2012.01379.x

  17. Enzyme- and Transporter-Mediated Drug Interactions with Small Molecule Tyrosine Kinase Inhibitors

    Journal of Pharmaceutical Sciences

    Volume 103, Issue 12, December 2014, Pages: 3810–3833, Jie Shao, John S. Markowitz, Di Bei and Guohua An

    Article first published online : 10 OCT 2014, DOI: 10.1002/jps.24113

  18. You have free access to this content
    Inherent sex-dependent regulation of human hepatic CYP3A5

    British Journal of Pharmacology

    Volume 168, Issue 4, February 2013, Pages: 988–1000, Chellappagounder Thangavel, Ettickan Boopathi and Bernard H Shapiro

    Article first published online : 24 JAN 2013, DOI: 10.1111/j.1476-5381.2012.02222.x

  19. CYP3AP1*3 Allele Is Associated With Lipid-Lowering Efficacy of Simvastatin and Atorvastatin in Chinese Women

    The Journal of Clinical Pharmacology

    Volume 51, Issue 2, February 2011, Pages: 181–188, Yan-Peng Li, Li-rong Zhang, Min Jia and Xiang-Jie Hu

    Article first published online : 7 MAR 2013, DOI: 10.1177/0091270010370589

  20. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5

    Clinical Pharmacology & Therapeutics

    Volume 78, Issue 6, December 2005, Pages: 605–618, Stéphane J. Mouly, Chris Matheny, Mary F. Paine, Glenn Smith, Jatinder Lamba, Vishal Lamba, Susan N. Pusek, Erin G. Schuetz, Paul W. Stewart and Paul B. Watkins

    Article first published online : 7 DEC 2005, DOI: 10.1016/j.clpt.2005.08.014