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There are 48406 results for: content related to: Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment, and on progression

  1. MicroRNA and mRNA expression profiling in metastatic melanoma reveal associations with BRAF mutation and patient prognosis

    Pigment Cell & Melanoma Research

    Volume 28, Issue 3, May 2015, Pages: 254–266, Varsha Tembe, Sarah-Jane Schramm, Mitchell S. Stark, Ellis Patrick, Vivek Jayaswal, Yue Hang Tang, Andrew Barbour, Nicholas K. Hayward, John F. Thompson, Richard A. Scolyer, Yee Hwa Yang and Graham J. Mann

    Version of Record online : 5 JAN 2015, DOI: 10.1111/pcmr.12343

  2. The broad-spectrum receptor tyrosine kinase inhibitor dovitinib suppresses growth of BRAF-mutant melanoma cells in combination with other signaling pathway inhibitors

    Pigment Cell & Melanoma Research

    Volume 28, Issue 4, July 2015, Pages: 417–430, Casey G. Langdon, Matthew A. Held, James T. Platt, Katrina Meeth, Pinar Iyidogan, Ramanaiah Mamillapalli, Andrew B. Koo, Michael Klein, Zongzhi Liu, Marcus W. Bosenberg and David F. Stern

    Version of Record online : 6 MAY 2015, DOI: 10.1111/pcmr.12376

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    Metastatic pathways in patients with cutaneous melanoma

    Pigment Cell & Melanoma Research

    Volume 30, Issue 1, January 2017, Pages: 13–27, Nikki R. Adler, Andrew Haydon, Catriona A. McLean, John W. Kelly and Victoria J. Mar

    Version of Record online : 30 NOV 2016, DOI: 10.1111/pcmr.12544

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    Genetics of melanocytic nevi

    Pigment Cell & Melanoma Research

    Volume 28, Issue 6, November 2015, Pages: 661–672, Mi Ryung Roh, Philip Eliades, Sameer Gupta and Hensin Tsao

    Version of Record online : 17 OCT 2015, DOI: 10.1111/pcmr.12412

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    Emerging molecular targets in melanoma invasion and metastasis

    Pigment Cell & Melanoma Research

    Volume 26, Issue 1, January 2013, Pages: 39–57, Jose L. Orgaz and Victoria Sanz-Moreno

    Version of Record online : 21 NOV 2012, DOI: 10.1111/pcmr.12041

  6. You have full text access to this OnlineOpen article
    Microphthalmia-associated transcription factor in melanoma development and MAP-kinase pathway targeted therapy

    Pigment Cell & Melanoma Research

    Volume 28, Issue 4, July 2015, Pages: 390–406, Claudia Wellbrock and Imanol Arozarena

    Version of Record online : 17 APR 2015, DOI: 10.1111/pcmr.12370

  7. Paradoxical oncogenesis: are all BRAF inhibitors equal?

    Pigment Cell & Melanoma Research

    Volume 26, Issue 5, September 2013, Pages: 611–615, Alexander M. Menzies, Richard F. Kefford and Georgina V. Long

    Version of Record online : 19 JUL 2013, DOI: 10.1111/pcmr.12132

  8. You have full text access to this OnlineOpen article
    Identification of PLX4032-resistance mechanisms and implications for novel RAF inhibitors

    Pigment Cell & Melanoma Research

    Volume 27, Issue 2, March 2014, Pages: 253–262, Jaehyuk Choi, Sean F. Landrette, Tiffany Wang, Perry Evans, Antonella Bacchiocchi, Robert Bjornson, Elaine Cheng, Amy L. Stiegler, Symon Gathiaka, Orlando Acevedo, Titus J. Boggon, Michael Krauthammer, Ruth Halaban and Tian Xu

    Version of Record online : 6 JAN 2014, DOI: 10.1111/pcmr.12197

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    Mechanisms of intrinsic and acquired resistance to kinase-targeted therapies

    Pigment Cell & Melanoma Research

    Volume 25, Issue 6, November 2012, Pages: 819–831, Shubha Bagrodia, Tod Smeal and Robert T. Abraham

    Version of Record online : 14 SEP 2012, DOI: 10.1111/pcmr.12007

  10. Detrimental effects of melanocortin-1 receptor (MC1R) variants on the clinical outcomes of BRAF V600 metastatic melanoma patients treated with BRAF inhibitors

    Pigment Cell & Melanoma Research

    Volume 29, Issue 6, November 2016, Pages: 679–687, Michele Guida, Sabino Strippoli, Anna Ferretta, Nicola Bartolomeo, Letizia Porcelli, Immacolata Maida, Amalia Azzariti, Stefania Tommasi, Claudia Grieco, Stefania Guida, Anna Albano, Vito Lorusso and Gabriella Guida

    Version of Record online : 17 NOV 2016, DOI: 10.1111/pcmr.12516

  11. PTEN regulates IGF-1R-mediated therapy resistance in melanoma

    Pigment Cell & Melanoma Research

    Volume 28, Issue 5, September 2015, Pages: 572–589, Jun Wang, Tobias Sinnberg, Heike Niessner, Rebecca Dölker, Birgit Sauer, Wolfgang E. Kempf, Friedegund Meier, Nick Leslie and Birgit Schittek

    Version of Record online : 16 AUG 2015, DOI: 10.1111/pcmr.12390

  12. MicroRNA-125a promotes resistance to BRAF inhibitors through suppression of the intrinsic apoptotic pathway

    Pigment Cell & Melanoma Research

    Volume 30, Issue 3, May 2017, Pages: 328–338, Lisa Koetz-Ploch, Douglas Hanniford, Igor Dolgalev, Elena Sokolova, Judy Zhong, Marta Díaz-Martínez, Emily Bernstein, Farbod Darvishian, Keith T. Flaherty, Paul B. Chapman, Hussein Tawbi and Eva Hernando

    Version of Record online : 19 APR 2017, DOI: 10.1111/pcmr.12578

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    Cyclin-dependent kinases as therapeutic targets in melanoma

    Pigment Cell & Melanoma Research

    Volume 27, Issue 3, May 2014, Pages: 351–365, David M. Miller and Keith T. Flaherty

    Version of Record online : 10 FEB 2014, DOI: 10.1111/pcmr.12211

  14. Clinical and pathological associations of the activating RAC1 P29S mutation in primary cutaneous melanoma

    Pigment Cell & Melanoma Research

    Volume 27, Issue 6, November 2014, Pages: 1117–1125, Victoria J. Mar, Stephen Q. Wong, Aleksandra Logan, Trung Nguyen, Jonathan Cebon, John W. Kelly, Rory Wolfe, Alexander Dobrovic, Catriona McLean and Grant A. McArthur

    Version of Record online : 4 AUG 2014, DOI: 10.1111/pcmr.12295

  15. Near-genomewide RNAi screening for regulators of BRAFV600E-induced senescence identifies RASEF, a gene epigenetically silenced in melanoma

    Pigment Cell & Melanoma Research

    Volume 27, Issue 4, July 2014, Pages: 640–652, Joanna Kaplon, Cornelia Hömig-Hölzel, Linda Gao, Katrin Meissl, Els M. E. Verdegaal, Sjoerd H. van der Burg, Remco van Doorn and Daniel S. Peeper

    Version of Record online : 14 MAY 2014, DOI: 10.1111/pcmr.12248

  16. miR-200c/Bmi1 axis and epithelial–mesenchymal transition contribute to acquired resistance to BRAF inhibitor treatment

    Pigment Cell & Melanoma Research

    Volume 28, Issue 4, July 2015, Pages: 431–441, Shujing Liu, Michael T. Tetzlaff, Tao Wang, Ruifeng Yang, Lin Xie, Gao Zhang, Clemens Krepler, Min Xiao, Marilda Beqiri, Wei Xu, Giorgos Karakousis, Lynn Schuchter, Ravi K. Amaravadi, Weiting Xu, Zhi Wei, Meenhard Herlyn, Yuan Yao, Litao Zhang, Yingjie Wang, Lin Zhang and Xiaowei Xu

    Version of Record online : 16 MAY 2015, DOI: 10.1111/pcmr.12379

  17. Disturbed protein–protein interaction networks in metastatic melanoma are associated with worse prognosis and increased functional mutation burden

    Pigment Cell & Melanoma Research

    Volume 26, Issue 5, September 2013, Pages: 708–722, Sarah-Jane Schramm, Simone S. Li, Vivek Jayaswal, David C. Y. Fung, Anna E. Campain, Chi N. I. Pang, Richard A. Scolyer, Yee Hwa Yang, Graham J. Mann and Marc R. Wilkins

    Version of Record online : 5 JUL 2013, DOI: 10.1111/pcmr.12126

  18. Selective RAF inhibitor impairs ERK1/2 phosphorylation and growth in mutant NRAS, vemurafenib-resistant melanoma cells

    Pigment Cell & Melanoma Research

    Volume 26, Issue 4, July 2013, Pages: 509–517, Kaitlyn Le, Erik S. Blomain, Ulrich Rodeck and Andrew E. Aplin

    Version of Record online : 8 APR 2013, DOI: 10.1111/pcmr.12092

  19. Recurrent BRAF kinase fusions in melanocytic tumors offer an opportunity for targeted therapy

    Pigment Cell & Melanoma Research

    Volume 26, Issue 6, November 2013, Pages: 845–851, Thomas Botton, Iwei Yeh, Tyrrell Nelson, Swapna S. Vemula, Alyssa Sparatta, Maria C. Garrido, Maryline Allegra, Stephane Rocchi, Philippe Bahadoran, Timothy H. McCalmont, Philip E. LeBoit, Elizabeth A. Burton, Gideon Bollag, Robert Ballotti and Boris C. Bastian

    Version of Record online : 19 AUG 2013, DOI: 10.1111/pcmr.12148

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    Genetics of melanoma progression: the rise and fall of cell senescence

    Pigment Cell & Melanoma Research

    Volume 29, Issue 2, March 2016, Pages: 122–140, Dorothy C. Bennett

    Version of Record online : 18 NOV 2015, DOI: 10.1111/pcmr.12422