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There are 13135 results for: content related to: A small leak may sink a great ship but what does it do to the heart?

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    Increased Ca2+ leak and spatiotemporal coherence of Ca2+ release in cardiomyocytes during β-adrenergic stimulation

    The Journal of Physiology

    Volume 588, Issue 1, January 2010, Pages: 225–242, Jakob Ogrodnik and Ernst Niggli

    Version of Record online : 4 JAN 2010, DOI: 10.1113/jphysiol.2009.181800

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    Regulation of sarcoplasmic reticulum Ca2+ leak by cytosolic Ca2+ in rabbit ventricular myocytes

    The Journal of Physiology

    Volume 589, Issue 24, December 2011, Pages: 6039–6050, Elisa Bovo, Stefan R. Mazurek, Lothar A. Blatter and Aleksey V. Zima

    Version of Record online : 14 DEC 2011, DOI: 10.1113/jphysiol.2011.214171

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    Ca2+ spark-dependent and -independent sarcoplasmic reticulum Ca2+ leak in normal and failing rabbit ventricular myocytes

    The Journal of Physiology

    Volume 588, Issue 23, December 2010, Pages: 4743–4757, Aleksey V. Zima, Elisa Bovo, Donald M. Bers and Lothar A. Blatter

    Version of Record online : 30 NOV 2010, DOI: 10.1113/jphysiol.2010.197913

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    Paradoxical SR Ca2+ release in guinea-pig cardiac myocytes after β-adrenergic stimulation revealed by two-photon photolysis of caged Ca2+

    The Journal of Physiology

    Volume 565, Issue 3, June 2005, Pages: 801–813, Nicolas Lindegger and Ernst Niggli

    Version of Record online : 22 JUN 2005, DOI: 10.1113/jphysiol.2005.084376

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    Cytosolic energy reserves determine the effect of glycolytic sugar phosphates on sarcoplasmic reticulum Ca2+ release in cat ventricular myocytes

    The Journal of Physiology

    Volume 577, Issue 1, November 2006, Pages: 281–293, Aleksey V. Zima, Jens Kockskämper and Lothar A. Blatter

    Version of Record online : 8 NOV 2006, DOI: 10.1113/jphysiol.2006.117242

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    Pyruvate Modulates Cardiac Sarcoplasmic Reticulum Ca2+ Release in Rats Via Mitochondria-Dependent and -Independent Mechanisms

    The Journal of Physiology

    Volume 550, Issue 3, August 2003, Pages: 765–783, Aleksey V. Zima, Jens Kockskämper, Rafael Mejia-Alvarez and Lothar A. Blatter

    Version of Record online : 16 JUL 2004, DOI: 10.1113/jphysiol.2003.040345

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    Alteration of sarcoplasmic reticulum Ca2+ release termination by ryanodine receptor sensitization and in heart failure

    The Journal of Physiology

    Volume 587, Issue 21, November 2009, Pages: 5197–5209, Timothy L. Domeier, Lothar A. Blatter and Aleksey V. Zima

    Version of Record online : 30 OCT 2009, DOI: 10.1113/jphysiol.2009.177576

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    Effects of Mg2+ and SR luminal Ca2+ on caffeine-induced Ca2+ release in skeletal muscle from humans susceptible to malignant hyperthermia

    The Journal of Physiology

    Volume 544, Issue 1, October 2002, Pages: 85–95, Adrian M. Duke, Philip M. Hopkins and Derek S. Steele

    Version of Record online : 22 JUL 2004, DOI: 10.1113/jphysiol.2002.022749

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    Dihydropyridine receptors actively control gating of ryanodine receptors in resting mouse skeletal muscle fibres

    The Journal of Physiology

    Volume 590, Issue 23, December 2012, Pages: 6027–6036, Gaëlle Robin and Bruno Allard

    Version of Record online : 19 OCT 2012, DOI: 10.1113/jphysiol.2012.237321

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    Reactive oxygen species contribute to the development of arrhythmogenic Ca2+ waves during β-adrenergic receptor stimulation in rabbit cardiomyocytes

    The Journal of Physiology

    Volume 590, Issue 14, July 2012, Pages: 3291–3304, Elisa Bovo, Stephen L. Lipsius and Aleksey V. Zima

    Version of Record online : 24 JUL 2012, DOI: 10.1113/jphysiol.2012.230748

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    Modulation of excitation–contraction coupling by isoproterenol in cardiomyocytes with controlled SR Ca2+ load and Ca2+ current trigger

    The Journal of Physiology

    Volume 556, Issue 2, April 2004, Pages: 463–480, Kenneth S. Ginsburg and Donald M. Bers

    Version of Record online : 28 JUN 2008, DOI: 10.1113/jphysiol.2003.055384

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    FKBP12.6 overexpression does not protect against remodelling after myocardial infarction

    Experimental Physiology

    Volume 98, Issue 1, January 2013, Pages: 134–148, Virginie Bito, Liesbeth Biesmans, Barnabas Gellen, Gudrun Antoons, Niall Macquaide, Patricia Rouet-Benzineb, Mylène Pezet, Jean-Jacques Mercadier and Karin R. Sipido

    Version of Record online : 18 JUL 2012, DOI: 10.1113/expphysiol.2011.064089

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    Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes

    The Journal of Physiology

    Volume 589, Issue 24, December 2011, Pages: 6063–6080, Beth A. Altschafl, Demetrios A. Arvanitis, Oscar Fuentes, Qunying Yuan, Evangelia G. Kranias and Héctor H. Valdivia

    Version of Record online : 14 DEC 2011, DOI: 10.1113/jphysiol.2011.215988

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    Effects of ADP on action potential-induced force responses in mechanically skinned rat fast-twitch fibres

    The Journal of Physiology

    Volume 559, Issue 2, September 2004, Pages: 433–447, W. A. Macdonald and D. G. Stephenson

    Version of Record online : 25 AUG 2004, DOI: 10.1113/jphysiol.2004.067603

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    The effects of membrane potential, SR Ca2+ content and RyR responsiveness on systolic Ca2+ alternans in rat ventricular myocytes

    The Journal of Physiology

    Volume 587, Issue 6, March 2009, Pages: 1283–1292, Yatong Li, Mary E. Díaz, David A. Eisner and Stephen O'Neill

    Version of Record online : 13 MAR 2009, DOI: 10.1113/jphysiol.2008.164368

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    Redox modification of ryanodine receptors by mitochondria-derived reactive oxygen species contributes to aberrant Ca2+ handling in ageing rabbit hearts

    The Journal of Physiology

    Volume 591, Issue 23, December 2013, Pages: 5895–5911, Leroy L. Cooper, Weiyan Li, Yichun Lu, Jason Centracchio, Radmila Terentyeva, Gideon Koren and Dmitry Terentyev

    Version of Record online : 17 OCT 2013, DOI: 10.1113/jphysiol.2013.260521

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    Effects of cytosolic NADH/NAD+ levels on sarcoplasmic reticulum Ca2+ release in permeabilized rat ventricular myocytes

    The Journal of Physiology

    Volume 555, Issue 3, 16 March 2004, Pages: 727–741, Aleksey V. Zima, Julio A. Copello and Lothar A. Blatter

    Version of Record online : 9 MAR 2004, DOI: 10.1113/jphysiol.2003.055848

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    JTV519 (K201) reduces sarcoplasmic reticulum Ca2+ leak and improves diastolic function in vitro in murine and human non-failing myocardium

    British Journal of Pharmacology

    Volume 167, Issue 3, October 2012, Pages: 493–504, M Sacherer, S Sedej, P Wakuła, M Wallner, MA Vos, J Kockskämper, P Stiegler, M Sereinigg, D von Lewinski, G Antoons, BM Pieske, FR Heinzel and CONTICA investigators

    Version of Record online : 5 SEP 2012, DOI: 10.1111/j.1476-5381.2012.01995.x

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    β-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca2+ threshold for Ca2+ wave generation

    The Journal of Physiology

    Volume 590, Issue 23, December 2012, Pages: 6093–6108, Timothy L. Domeier, Joshua T. Maxwell and Lothar A. Blatter

    Version of Record online : 23 OCT 2012, DOI: 10.1113/jphysiol.2012.236117

  20. You have free access to this content
    A cardiac dihydropyridine receptor II-III loop peptide inhibits resting Ca2+ sparks in ferret ventricular myocytes

    The Journal of Physiology

    Volume 537, Issue 1, November 2001, Pages: 17–26, Yanxia Li and Donald M. Bers

    Version of Record online : 5 AUG 2004, DOI: 10.1111/j.1469-7793.2001.0017k.x