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There are 14619 results for: content related to: A small leak may sink a great ship but what does it do to the heart?

  1. You have free access to this content
    Regulation of sarcoplasmic reticulum Ca2+ leak by cytosolic Ca2+ in rabbit ventricular myocytes

    The Journal of Physiology

    Volume 589, Issue 24, December 2011, Pages: 6039–6050, Elisa Bovo, Stefan R. Mazurek, Lothar A. Blatter and Aleksey V. Zima

    Article first published online : 14 DEC 2011, DOI: 10.1113/jphysiol.2011.214171

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    Ca2+ spark-dependent and -independent sarcoplasmic reticulum Ca2+ leak in normal and failing rabbit ventricular myocytes

    The Journal of Physiology

    Volume 588, Issue 23, December 2010, Pages: 4743–4757, Aleksey V. Zima, Elisa Bovo, Donald M. Bers and Lothar A. Blatter

    Article first published online : 30 NOV 2010, DOI: 10.1113/jphysiol.2010.197913

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    Increased Ca2+ leak and spatiotemporal coherence of Ca2+ release in cardiomyocytes during β-adrenergic stimulation

    The Journal of Physiology

    Volume 588, Issue 1, January 2010, Pages: 225–242, Jakob Ogrodnik and Ernst Niggli

    Article first published online : 4 JAN 2010, DOI: 10.1113/jphysiol.2009.181800

  4. You have free access to this content
    Dihydropyridine receptors actively control gating of ryanodine receptors in resting mouse skeletal muscle fibres

    The Journal of Physiology

    Volume 590, Issue 23, December 2012, Pages: 6027–6036, Gaëlle Robin and Bruno Allard

    Article first published online : 19 OCT 2012, DOI: 10.1113/jphysiol.2012.237321

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    Role of glycogen availability in sarcoplasmic reticulum Ca2+ kinetics in human skeletal muscle

    The Journal of Physiology

    Volume 589, Issue 3, February 2011, Pages: 711–725, Niels Ørtenblad, Joachim Nielsen, Bengt Saltin and Hans-Christer Holmberg

    Article first published online : 28 JAN 2011, DOI: 10.1113/jphysiol.2010.195982

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    Modulation of contractile apparatus Ca2+ sensitivity and disruption of excitation–contraction coupling by S-nitrosoglutathione in rat muscle fibres

    The Journal of Physiology

    Volume 589, Issue 9, May 2011, Pages: 2181–2196, T. L. Dutka, J. P. Mollica, G. S. Posterino and G. D. Lamb

    Article first published online : 27 APR 2011, DOI: 10.1113/jphysiol.2010.200451

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    Dual role of junctin in the regulation of ryanodine receptors and calcium release in cardiac ventricular myocytes

    The Journal of Physiology

    Volume 589, Issue 24, December 2011, Pages: 6063–6080, Beth A. Altschafl, Demetrios A. Arvanitis, Oscar Fuentes, Qunying Yuan, Evangelia G. Kranias and Héctor H. Valdivia

    Article first published online : 14 DEC 2011, DOI: 10.1113/jphysiol.2011.215988

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    β-Adrenergic stimulation increases the intra-sarcoplasmic reticulum Ca2+ threshold for Ca2+ wave generation

    The Journal of Physiology

    Volume 590, Issue 23, December 2012, Pages: 6093–6108, Timothy L. Domeier, Joshua T. Maxwell and Lothar A. Blatter

    Article first published online : 23 OCT 2012, DOI: 10.1113/jphysiol.2012.236117

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    Reactive oxygen species contribute to the development of arrhythmogenic Ca2+ waves during β-adrenergic receptor stimulation in rabbit cardiomyocytes

    The Journal of Physiology

    Volume 590, Issue 14, July 2012, Pages: 3291–3304, Elisa Bovo, Stephen L. Lipsius and Aleksey V. Zima

    Article first published online : 24 JUL 2012, DOI: 10.1113/jphysiol.2012.230748

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    Differential sensitivity of Ca2+ wave and Ca2+ spark events to ruthenium red in isolated permeabilised rabbit cardiomyocytes

    The Journal of Physiology

    Volume 588, Issue 23, December 2010, Pages: 4731–4742, N. MacQuaide, H. R. Ramay, E. A. Sobie and G. L. Smith

    Article first published online : 30 NOV 2010, DOI: 10.1113/jphysiol.2010.193375

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    Defects in Ca2+ release associated with local expression of pathological ryanodine receptors in mouse muscle fibres

    The Journal of Physiology

    Volume 589, Issue 22, November 2011, Pages: 5361–5382, Romain Lefebvre, Claude Legrand, Estela González-Rodríguez, Linda Groom, Robert T. Dirksen and Vincent Jacquemond

    Article first published online : 14 NOV 2011, DOI: 10.1113/jphysiol.2011.216408

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    Increased fatigue resistance linked to Ca2+-stimulated mitochondrial biogenesis in muscle fibres of cold-acclimated mice

    The Journal of Physiology

    Volume 588, Issue 21, November 2010, Pages: 4275–4288, Joseph D. Bruton, Jan Aydin, Takashi Yamada, Irina G. Shabalina, Niklas Ivarsson, Shi-Jin Zhang, Masanobu Wada, Pasi Tavi, Jan Nedergaard, Abram Katz and Håkan Westerblad

    Article first published online : 29 OCT 2010, DOI: 10.1113/jphysiol.2010.198598

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    Data-based theoretical identification of subcellular calcium compartments and estimation of calcium dynamics in cardiac myocytes

    The Journal of Physiology

    Volume 590, Issue 18, September 2012, Pages: 4423–4446, Leonid Livshitz, Karoly Acsai, Gudrun Antoons, Karin Sipido and Yoram Rudy

    Article first published online : 14 SEP 2012, DOI: 10.1113/jphysiol.2012.228791

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    Redox modification of ryanodine receptors by mitochondria-derived reactive oxygen species contributes to aberrant Ca2+ handling in ageing rabbit hearts

    The Journal of Physiology

    Volume 591, Issue 23, December 2013, Pages: 5895–5911, Leroy L. Cooper, Weiyan Li, Yichun Lu, Jason Centracchio, Radmila Terentyeva, Gideon Koren and Dmitry Terentyev

    Article first published online : 17 OCT 2013, DOI: 10.1113/jphysiol.2013.260521

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    ‘Eventless’ InsP3-dependent SR-Ca2+ release affecting atrial Ca2+ sparks

    The Journal of Physiology

    Volume 591, Issue 8, April 2013, Pages: 2103–2111, Tamara Horn, Nina D. Ullrich and Marcel Egger

    Article first published online : 4 MAR 2013, DOI: 10.1113/jphysiol.2012.247288

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    Paying the piper: the cost of Ca2+ pumping during the mating call of toadfish

    The Journal of Physiology

    Volume 589, Issue 22, November 2011, Pages: 5467–5484, Claire L. Harwood, Iain S. Young, Boris A. Tikunov, Stephen Hollingworth, Stephen M. Baylor and Lawrence C. Rome

    Article first published online : 14 NOV 2011, DOI: 10.1113/jphysiol.2011.211979

  17. You have free access to this content
    Facilitation of cytosolic calcium wave propagation by local calcium uptake into the sarcoplasmic reticulum in cardiac myocytes

    The Journal of Physiology

    Volume 590, Issue 23, December 2012, Pages: 6037–6045, Joshua T. Maxwell and Lothar A. Blatter

    Article first published online : 15 OCT 2012, DOI: 10.1113/jphysiol.2012.239434

  18. You have free access to this content
    JTV519 (K201) reduces sarcoplasmic reticulum Ca2+ leak and improves diastolic function in vitro in murine and human non-failing myocardium

    British Journal of Pharmacology

    Volume 167, Issue 3, October 2012, Pages: 493–504, M Sacherer, S Sedej, P Wakuła, M Wallner, MA Vos, J Kockskämper, P Stiegler, M Sereinigg, D von Lewinski, G Antoons, BM Pieske, FR Heinzel and CONTICA investigators

    Article first published online : 5 SEP 2012, DOI: 10.1111/j.1476-5381.2012.01995.x

  19. Regulation of RyR2 by Sarcoplasmic Reticulum Ca2+

    Clinical and Experimental Pharmacology and Physiology

    Accepted manuscript online: 21 JAN 2015, Joe Z Zhang, Helen MM Waddell and Peter P Jones

    DOI: 10.1111/1440-1681.12364

  20. You have free access to this content
    Dual effects of tetracaine on spontaneous calcium release in rat ventricular myocytes.

    The Journal of Physiology

    Volume 500, Issue 2, April 15, 1997, Pages: 297–309, S Györke, V Lukyanenko and I Györke

    Article first published online : 15 APR 1997, DOI: 10.1113/jphysiol.1997.sp022021