Search Results

There are 26921 results for: content related to: Increased Systemic Exposure of Fimasartan, an Angiotensin II Receptor Antagonist, by Ketoconazole and Rifampicin

  1. You have free access to this content
    Comparing Various In Vitro Prediction Criteria to Assess the Potential of a New Molecular Entity to Inhibit Organic Anion Transporting Polypeptide 1B1

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S59–S72, Jayabharathi Vaidyanathan, Kenta Yoshida, Vikram Arya and Lei Zhang

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.723

  2. You have free access to this content
    Importance of Hepatic Transporters in Clinical Disposition of Drugs and Their Metabolites

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S23–S39, Mitesh Patel, Kunal S. Taskar and Maciej J. Zamek-Gliszczynski

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.671

  3. You have free access to this content
    Evaluation of Proposed In Vivo Probe Substrates and Inhibitors for Phenotyping Transporter Activity in Humans

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S82–S98, Jeremiah D. Momper, Shirley M. Tsunoda and Joseph D. Ma

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.736

  4. Absolute bioavailability and pharmacokinetics of the angiotensin II receptor antagonist fimasartan in healthy subjects

    The Journal of Clinical Pharmacology

    Volume 56, Issue 5, May 2016, Pages: 576–580, Jong-Lyul Ghim, Soo Heui Paik, M. Hasanuzzaman, Yong Ha Chi, Hyang-Ki Choi, Dong-Hyun Kim and Jae-Gook Shin

    Version of Record online : 24 DEC 2015, DOI: 10.1002/jcph.618

  5. You have full text access to this OnlineOpen article
    More Power to OATP1B1: An Evaluation of Sample Size in Pharmacogenetic Studies Using a Rosuvastatin PBPK Model for Intestinal, Hepatic, and Renal Transporter-Mediated Clearances

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S132–S142, Ariane Emami Riedmaier, Howard Burt, Khaled Abduljalil and Sibylle Neuhoff

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.669

  6. You have free access to this content
    Identification of drugs and drug metabolites as substrates of multidrug resistance protein 2 (MRP2) using triple-transfected MDCK-OATP1B1-UGT1A1-MRP2 cells

    British Journal of Pharmacology

    Volume 165, Issue 6, March 2012, Pages: 1836–1847, C Fahrmayr, J König, D Auge, M Mieth and MF Fromm

    Version of Record online : 22 FEB 2012, DOI: 10.1111/j.1476-5381.2011.01672.x

  7. Pre-incubation with cyclosporine A potentiates its inhibitory effects on pitavastatin uptake mediated by recombinantly expressed cynomolgus monkey hepatic organic anion transporting polypeptide

    Biopharmaceutics & Drug Disposition

    Volume 37, Issue 8, November 2016, Pages: 479–490, Tsuyoshi Takahashi, Tatsuyuki Ohtsuka, Yasuhiro Uno, Masahiro Utoh, Hiroshi Yamazaki and Toshiyuki Kume

    Version of Record online : 14 OCT 2016, DOI: 10.1002/bdd.2039

  8. You have free access to this content
    Long-lasting inhibitory effects of saquinavir and ritonavir on OATP1B1-mediated uptake

    Journal of Pharmaceutical Sciences

    Volume 102, Issue 9, September 2013, Pages: 3427–3435, Yoshihisa Shitara, Kumiko Takeuchi and Toshiharu Horie

    Version of Record online : 25 FEB 2013, DOI: 10.1002/jps.23477

  9. You have free access to this content
    Pitavastatin is a more sensitive and selective organic anion-transporting polypeptide 1B clinical probe than rosuvastatin

    British Journal of Clinical Pharmacology

    Volume 78, Issue 3, September 2014, Pages: 587–598, Thomayant Prueksaritanont, Xiaoyan Chu, Raymond Evers, Stephanie O. Klopfer, Luzelena Caro, Prajakti A. Kothare, Cynthia Dempsey, Scott Rasmussen, Robert Houle, Grace Chan, Xiaoxin Cai, Robert Valesky, Iain P. Fraser and S. Aubrey Stoch

    Version of Record online : 21 AUG 2014, DOI: 10.1111/bcp.12377

  10. Ethnic Variability in the Plasma Exposures of OATP1B1 Substrates Such as HMG-CoA Reductase Inhibitors: A Kinetic Consideration of Its Mechanism

    Clinical Pharmacology & Therapeutics

    Volume 94, Issue 1, July 2013, Pages: 37–51, Y Tomita, K Maeda and Y Sugiyama

    Version of Record online : 7 NOV 2012, DOI: 10.1038/clpt.2012.221

  11. You have free access to this content
    Role of Hepatic Drug Transporters in Drug Development

    The Journal of Clinical Pharmacology

    Volume 56, Issue S7, July 2016, Pages: S11–S22, Houfu Liu and Jasminder Sahi

    Version of Record online : 7 JUL 2016, DOI: 10.1002/jcph.703

  12. Poster Session I

    Clinical Pharmacology & Therapeutics

    Volume 97, Issue S1, February 2015, Pages: S21–S56,

    Version of Record online : 22 JAN 2015, DOI: 10.1002/cpt.50

  13. Suitability of digoxin as a P-glycoprotein probe: Implications of other transporters on sensitivity and specificity

    The Journal of Clinical Pharmacology

    Volume 54, Issue 1, January 2014, Pages: 3–13, Ahmed M. Nader and David R. Foster

    Version of Record online : 26 OCT 2013, DOI: 10.1002/jcph.200

  14. OATP1B1 Polymorphism as a Determinant of Erythromycin Disposition

    Clinical Pharmacology & Therapeutics

    Volume 92, Issue 5, November 2012, Pages: 642–650, C S Lancaster, G H Bruun, C J Peer, T S Mikkelsen, T J Corydon, A A Gibson, S Hu, S J Orwick, R H J Mathijssen, W D Figg, S D Baker and A Sparreboom

    Version of Record online : 19 SEP 2012, DOI: 10.1038/clpt.2012.106

  15. You have free access to this content
    Role of transmembrane domain 10 for the function of organic anion transporting polypeptide 1B1

    Protein Science

    Volume 18, Issue 11, November 2009, Pages: 2298–2306, Chunshan Gui and Bruno Hagenbuch

    Version of Record online : 16 SEP 2009, DOI: 10.1002/pro.240

  16. Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril

    Clinical Pharmacology & Therapeutics

    Volume 79, Issue 5, May 2006, Pages: 427–439, Kazuya Maeda, Ichiro Ieiri, Kuninobu Yasuda, Akiharu Fujino, Hiroaki Fujiwara, Kenji Otsubo, Masaru Hirano, Takao Watanabe, Yoshiaki Kitamura, Hiroyuki Kusuhara and Yuichi Sugiyama

    Version of Record online : 11 APR 2006, DOI: 10.1016/j.clpt.2006.01.011

  17. American Society for Clinical Pharmacology and Therapeutics

    Clinical Pharmacology & Therapeutics

    Volume 101, Issue S1, February 2017, Pages: S5–S99,

    Version of Record online : 13 JAN 2017, DOI: 10.1002/cpt.570

  18. You have free access to this content
    Inhibition of the organic anion-transporting polypeptide 1B1 by quercetin: an in vitro and in vivo assessment

    British Journal of Clinical Pharmacology

    Volume 73, Issue 5, May 2012, Pages: 750–757, Lan-Xiang Wu, Cheng-Xian Guo, Wang-Qing Chen, Jing Yu, Qiang Qu, Yao Chen, Zhi-Rong Tan, Guo Wang, Lan Fan, Qing Li, Wei Zhang and Hong-Hao Zhou

    Version of Record online : 5 APR 2012, DOI: 10.1111/j.1365-2125.2011.04150.x

  19. Clinical drug interaction profile of idelalisib in healthy subjects

    The Journal of Clinical Pharmacology

    Volume 55, Issue 8, August 2015, Pages: 909–919, Feng Jin, Michelle Robeson, Huafeng Zhou, Candra Moyer, Sibylle Wilbert, Bernard Murray and Srini Ramanathan

    Version of Record online : 6 MAY 2015, DOI: 10.1002/jcph.495

  20. You have free access to this content
    Drug-Induced Liver Injury: The Role of Drug Metabolism and Transport

    The Journal of Clinical Pharmacology

    Volume 53, Issue 5, May 2013, Pages: 463–474, Alberto Corsini and Michele Bortolini

    Version of Record online : 22 FEB 2013, DOI: 10.1002/jcph.23