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There are 42918 results for: content related to: Targeting Signal-Transducer-and-Activator-of-Transcription-3 for Prevention and Therapy of Cancer

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    Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer

    Annals of the New York Academy of Sciences

    Volume 1171, Issue 1, August 2009, Pages: 59–76, Bharat B. Aggarwal, Ajaikumar B. Kunnumakkara, Kuzhuvelil B. Harikumar, Shan R. Gupta, Sheeja T. Tharakan, Cemile Koca, Sanjit Dey and Bokyung Sung

    Article first published online : 15 AUG 2009, DOI: 10.1111/j.1749-6632.2009.04911.x

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    STAT3 the oncogene – still eluding therapy?

    FEBS Journal

    Matthew S. Wake and Christine J. Watson

    Article first published online : 22 APR 2015, DOI: 10.1111/febs.13285

  3. STAT3 Serine 727 Phosphorylation: A Relevant Target to Radiosensitize Human Glioblastoma

    Brain Pathology

    Zangbéwendé Guy Ouédraogo, Mélanie Müller-Barthélémy, Jean-Louis Kemeny, Véronique Dedieu, Julian Biau, Toufic Khalil, Lala Ines Raoelfils, Adeline Granzotto, Bruno Pereira, Claude Beaudoin, Innocent Pierre Guissou, Marc Berger, Laurent Morel, Emmanuel Chautard and Pierre Verrelle

    Article first published online : 30 APR 2015, DOI: 10.1111/bpa.12254

  4. STAT3: A critical transcription activator in angiogenesis

    Medicinal Research Reviews

    Volume 28, Issue 2, March 2008, Pages: 185–200, Zhong Chen and Zhong Chao Han

    Article first published online : 24 APR 2007, DOI: 10.1002/med.20101

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    γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

    British Journal of Pharmacology

    Volume 163, Issue 2, May 2011, Pages: 283–298, Peramaiyan Rajendran, Feng Li, Kanjoormana Aryan Manu, Muthu K. Shanmugam, Ser Yue Loo, Alan Prem Kumar and Gautam Sethi

    Article first published online : 18 APR 2011, DOI: 10.1111/j.1476-5381.2010.01187.x

  6. Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion

    The Prostate

    Volume 72, Issue 1, January 2012, Pages: 82–89, Meng Sun, Chengfei Liu, Nagalakshmi Nadiminty, Wei Lou, Yezi Zhu, Joy Yang, Christopher P. Evans, Qinghua Zhou and Allen C. Gao

    Article first published online : 2 MAY 2011, DOI: 10.1002/pros.21409

  7. Growth factor signaling pathways as targets for prevention of epithelial carcinogenesis

    Molecular Carcinogenesis

    Volume 50, Issue 4, April 2011, Pages: 264–279, Okkyung Rho, Dae Joon Kim, Karou Kiguchi and John DiGiovanni

    Article first published online : 20 JUL 2010, DOI: 10.1002/mc.20665

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    Fluacrypyrim, a novel STAT3 activation inhibitor, induces cell cycle arrest and apoptosis in cancer cells harboring constitutively-active STAT3

    International Journal of Cancer

    Volume 127, Issue 6, 15 September 2010, Pages: 1259–1270, Zu-Yin Yu, Rui Huang, He Xiao, Wen-Feng Sun, Ya-Jun Shan, Bo Wang, Ting-Ting Zhao, Bo Dong, Zhen-Hu Zhao, Xiao-Lan Liu, Sheng-Qi Wang, Ri-Fang Yang, Qing-Liang Luo and Yu-Wen Cong

    Article first published online : 19 JAN 2010, DOI: 10.1002/ijc.25169

  9. Effective down-regulation of signal transducer and activator of transcription 3 (STAT3) by polyplexes of siRNA and lipid-substituted polyethyleneimine for sensitization of breast tumor cells to conventional chemotherapy

    Journal of Biomedical Materials Research Part A

    Volume 102, Issue 9, September 2014, Pages: 3216–3228, Arash Falamarzian, Hamidreza Montazeri Aliabadi, Ommoleila Molavi, John M. Seubert, Raymond Lai, Hasan Uludağ and Afsaneh Lavasanifar

    Article first published online : 25 OCT 2013, DOI: 10.1002/jbm.a.34992

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    Role of gp130-mediated signalling pathways in the heart and its impact on potential therapeutic aspects

    British Journal of Pharmacology

    Volume 153, Issue S1, March 2008, Pages: S414–S427, P Fischer and D Hilfiker-Kleiner

    Article first published online : 29 JAN 2009, DOI: 10.1038/bjp.2008.1

  11. Crosstalk between signaling pathways of adrenoreceptors and signal transducers and activators of transcription 3 (STAT3) in heart

    Acta Pharmacologica Sinica

    Volume 28, Issue 2, February 2007, Pages: 153–165, Kai-zheng GONG, Hui ZHANG, Jian-hai DU and You-yi ZHANG

    Article first published online : 7 FEB 2007, DOI: 10.1111/j.1745-7254.2007.00525.x

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    STAT3 activity is necessary and sufficient for the development of immune-mediated myocarditis in mice and promotes progression to dilated cardiomyopathy

    EMBO Molecular Medicine

    Volume 5, Issue 4, April 2013, Pages: 572–590, Annalisa Camporeale, Francesca Marino, Anna Papageorgiou, Paolo Carai, Sara Fornero, Steven Fletcher, Brent D. G. Page, Patrick Gunning, Marco Forni, Roberto Chiarle, Mara Morello, Ole Jensen, Renzo Levi, Stephane Heymans and Valeria Poli

    Article first published online : 5 MAR 2013, DOI: 10.1002/emmm.201201876

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    Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of transcription 3 activation pathway

    British Journal of Pharmacology

    Volume 161, Issue 3, October 2010, Pages: 541–554, Feng Li, Peramaiyan Rajendran and Gautam Sethi

    Article first published online : 10 MAY 2010, DOI: 10.1111/j.1476-5381.2010.00874.x

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    Crif1 is a novel transcriptional coactivator of STAT3

    The EMBO Journal

    Volume 27, Issue 4, February 20, 2008, Pages: 642–653, Min-chul Kwon, Bon-Kyoung Koo, Jin-Sook Moon, Yoon-Young Kim, Ki Cheol Park, Nam-Shik Kim, Mi Yi Kwon, Myung-Phil Kong, Ki-Jun Yoon, Sun-Kyoung Im, Jaewang Ghim, Yong-Mahn Han, Sung Key Jang, Minho Shong and Young-Yun Kong

    Article first published online : 17 JAN 2008, DOI: 10.1038/sj.emboj.7601986

  15. A Review: Phytochemicals Targeting JAK/STAT Signaling and IDO Expression in Cancer

    Phytotherapy Research

    Niroshaathevi Arumuggam, Neil A. Bhowmick and H. P. Vasantha Rupasinghe

    Article first published online : 18 MAR 2015, DOI: 10.1002/ptr.5327

  16. Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1

    Journal of Cellular Physiology

    Volume 227, Issue 5, May 2012, Pages: 2184–2195, Peramaiyan Rajendran, Feng Li, Muthu K. Shanmugam, Shireen Vali, Taher Abbasi, Shweta Kapoor, Kwang Seok Ahn, Alan Prem Kumar and Gautam Sethi

    Article first published online : 23 JAN 2012, DOI: 10.1002/jcp.22954

  17. Arctigenin enhances chemosensitivity of cancer cells to cisplatin through inhibition of the STAT3 signaling pathway

    Journal of Cellular Biochemistry

    Volume 112, Issue 10, October 2011, Pages: 2837–2849, Xiangyang Yao, Fenfen Zhu, Zhihui Zhao, Chang Liu, Lan Luo and Zhimin Yin

    Article first published online : 19 SEP 2011, DOI: 10.1002/jcb.23198

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    Cytokine-Induced Slowing of STAT3 Nuclear Import; Faster Basal Trafficking of the STAT3β Isoform


    Volume 15, Issue 9, September 2014, Pages: 946–960, Ivan H. W. Ng, Marie A. Bogoyevitch and David A. Jans

    Article first published online : 29 JUN 2014, DOI: 10.1111/tra.12181

  19. Nonreceptor Tyrosine Kinases

    Targeting Protein Kinases for Cancer Therapy

    David J. Matthews, Mary E. Gerritsen, Pages: 215–264, 2010

    Published Online : 11 MAR 2010, DOI: 10.1002/9780470555293.ch4

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    STAT3 Is Required for Proliferation and Maintenance of Multipotency in Glioblastoma Stem Cells


    Volume 27, Issue 10, October 2009, Pages: 2383–2392, Maureen M. Sherry, Andrew Reeves, Julian K. Wu and Brent H. Cochran

    Article first published online : 5 AUG 2009, DOI: 10.1002/stem.185