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There are 1940 results for: content related to: Cyclopamine-Mediated Hedgehog Pathway Inhibition Depletes Stem-Like Cancer Cells in Glioblastoma

  1. You have free access to this content
    In vitro and in vivo characterization of a novel hedgehog signaling antagonist in human glioblastoma cell lines

    International Journal of Cancer

    Volume 131, Issue 2, 15 July 2012, Pages: E33–E44, Pietro Ferruzzi, Federica Mennillo, Antonella De Rosa, Cinzia Giordano, Marco Rossi, Giovanni Benedetti, Roberta Magrini, Gal.la Pericot Mohr, Vincenzo Miragliotta, Letizia Magnoni, Elisa Mori, Russell Thomas, Patrizia Tunici and Annette Bakker

    Article first published online : 31 JAN 2012, DOI: 10.1002/ijc.27349

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    Hedgehog Signaling Regulates Brain Tumor-Initiating Cell Proliferation and Portends Shorter Survival for Patients with PTEN-Coexpressing Glioblastomas

    STEM CELLS

    Volume 26, Issue 12, December 2008, Pages: 3018–3026, Qijin Xu, Xiangpeng Yuan, Gentao Liu, Keith L. Black and John S. Yu

    Article first published online : 11 SEP 2008, DOI: 10.1634/stemcells.2008-0459

  3. Active sonic hedgehog signaling between androgen independent human prostate cancer cells and normal/benign but not cancer-associated prostate stromal cells

    The Prostate

    Volume 71, Issue 16, December 2011, Pages: 1711–1722, Katsumi Shigemura, Wen-Chin Huang, Xiangyan Li, Haiyen E. Zhau, Guodong Zhu, Akinobu Gotoh, Masato Fujisawa, Jingwu Xie, Fray F. Marshall and Leland W. K. Chung

    Article first published online : 25 APR 2011, DOI: 10.1002/pros.21388

  4. You have full text access to this Open Access content
    Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activation

    Cancer Science

    Volume 99, Issue 7, July 2008, Pages: 1377–1384, Shuntaro Nagai, Masafumi Nakamura, Kosuke Yanai, Junji Wada, Takashi Akiyoshi, Hiroshi Nakashima, Kenoki Ohuchida, Norihiro Sato, Masao Tanaka and Mitsuo Katano

    Article first published online : 11 APR 2008, DOI: 10.1111/j.1349-7006.2008.00822.x

  5. You have full text access to this OnlineOpen article
    A GLI1-p53 inhibitory loop controls neural stem cell and tumour cell numbers

    The EMBO Journal

    Volume 28, Issue 6, March 18, 2009, Pages: 663–676, Barbara Stecca and Ariel Ruiz i Altaba

    Article first published online : 12 FEB 2009, DOI: 10.1038/emboj.2009.16

  6. You have full text access to this OnlineOpen article
    Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

    EMBO Molecular Medicine

    Volume 1, Issue 6-7, September/October 2009, Pages: 338–351, Frédéric Varnat, Arnaud Duquet, Monica Malerba, Marie Zbinden, Christophe Mas, Pascal Gervaz and Ariel Ruiz i Altaba

    Article first published online : 27 AUG 2009, DOI: 10.1002/emmm.200900039

  7. Cyclopamine treatment of full-blown Hh/Ptch-associated RMS partially inhibits Hh/Ptch signaling, but not tumor growth

    Molecular Carcinogenesis

    Volume 47, Issue 5, May 2008, Pages: 361–372, Ines Ecke, Albert Rosenberger, Silvia Obenauer, Christian Dullin, Fritz Aberger, Sarah Kimmina, Stefan Schweyer and Heidi Hahn

    Article first published online : 26 OCT 2007, DOI: 10.1002/mc.20394

  8. Zic2 synergistically enhances Hedgehog signalling through nuclear retention of Gli1 in cervical cancer cells

    The Journal of Pathology

    Volume 225, Issue 4, December 2011, Pages: 525–534, David W Chan, Vincent WS Liu, Ling Yang Leung, Kwok Ming Yao, Karen KL Chan, Annie NY Cheung and Hextan YS Ngan

    Article first published online : 10 JUN 2011, DOI: 10.1002/path.2901

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    Sonic Hedgehog Pathway Inhibition Alters Epididymal Function as Assessed by the Development of Sperm Motility

    Journal of Andrology

    Volume 27, Issue 2, March-April 2006, Pages: 225–232, Terry T. Turner, Hyun J. Bang, Sharon A. Attipoe, Daniel S. Johnston and Jose L. Tomsig

    Article first published online : 2 JAN 2013, DOI: 10.2164/jandrol.05114

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    Hedgehog signaling is activated in subsets of esophageal cancers

    International Journal of Cancer

    Volume 118, Issue 1, 1 January 2006, Pages: 139–148, Xiaoli Ma, Tao Sheng, Yuanxin Zhang, Xiaoli Zhang, Jing He, Shuhong Huang, Kai Chen, Josh Sultz, Patrick A. Adegboyega, Hongwei Zhang and Jingwu Xie

    Article first published online : 7 JUL 2005, DOI: 10.1002/ijc.21295

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    Cross-signaling among phosphinositide-3 kinase, mitogen-activated protein kinase and sonic hedgehog pathways exists in esophageal cancer

    International Journal of Cancer

    Volume 129, Issue 2, 15 July 2011, Pages: 275–284, Lingyun Wei and Zhifei Xu

    Article first published online : 3 NOV 2010, DOI: 10.1002/ijc.25673

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    NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53

    The EMBO Journal

    Volume 29, Issue 15, August 4, 2010, Pages: 2659–2674, Marie Zbinden, Arnaud Duquet, Aiala Lorente-Trigos, Sandra-Nadia Ngwabyt, Isabel Borges and Ariel Ruiz i Altaba

    Article first published online : 25 JUN 2010, DOI: 10.1038/emboj.2010.137

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    Gli1 Induces G2/M Arrest and Apoptosis in Hippocampal but Not Tumor-Derived Neural Stem Cells

    STEM CELLS

    Volume 26, Issue 4, April 2008, Pages: 1027–1036, Katherine E. Galvin, Hong Ye, Derek J. Erstad, Rod Feddersen and Cynthia Wetmore

    Article first published online : 14 FEB 2008, DOI: 10.1634/stemcells.2007-0879

  14. Naturally Occurring Small-Molecule Inhibitors of Hedgehog/GLI-Mediated Transcription

    ChemBioChem

    Volume 9, Issue 7, May 5, 2008, Pages: 1082–1092, Takahiro Hosoya, Midori A. Arai, Takashi Koyano, Thaworn Kowithayakorn and Masami Ishibashi

    Article first published online : 20 MAR 2008, DOI: 10.1002/cbic.200700511

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    HEDGEHOG-GLI Signaling Drives Self-Renewal and Tumorigenicity of Human Melanoma-Initiating Cells

    STEM CELLS

    Volume 30, Issue 9, September 2012, Pages: 1808–1818, Roberta Santini, Maria C. Vinci, Silvia Pandolfi, Junia Y. Penachioni, Valentina Montagnani, Biagio Olivito, Riccardo Gattai, Nicola Pimpinelli, Gianni Gerlini, Lorenzo Borgognoni and Barbara Stecca

    Article first published online : 20 AUG 2012, DOI: 10.1002/stem.1160

  16. You have full text access to this Open Access content
    Hedgehog signal pathway is activated in ovarian carcinomas, correlating with cell proliferation: It's inhibition leads to growth suppression and apoptosis

    Cancer Science

    Volume 98, Issue 1, January 2007, Pages: 68–76, Xiaojun Chen, Akiko Horiuchi, Norihiko Kikuchi, Ryosuke Osada, Junko Yoshida, Tanri Shiozawa and Ikuo Konishi

    Article first published online : 3 NOV 2006, DOI: 10.1111/j.1349-7006.2006.00353.x

  17. Hedgehog pathway as a potential treatment target in human cholangiocarcinoma

    Journal of Hepato-Biliary-Pancreatic Sciences

    Volume 21, Issue 8, August 2014, Pages: 607–615, Dorothee Riedlinger, Marcus Bahra, Sabine Boas-Knoop, Steffen Lippert, Maren Bradtmöller, Katrin Guse, Daniel Seehofer, Roberta Bova, Igor M Sauer, Peter Neuhaus, Arend Koch and Carsten Kamphues

    Article first published online : 15 APR 2014, DOI: 10.1002/jhbp.107

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    Hedgehog and epithelial-mesenchymal transition signaling in normal and malignant epithelial cells of the esophagus

    International Journal of Cancer

    Volume 125, Issue 5, 1 September 2009, Pages: 1212–1221, Noriyuki Isohata, Kazuhiko Aoyagi, Tomoko Mabuchi, Hiroyuki Daiko, Masahide Fukaya, Hiroyuki Ohta, Kenji Ogawa, Teruhiko Yoshida and Hiroki Sasaki

    Article first published online : 27 FEB 2009, DOI: 10.1002/ijc.24400

  19. Inhibition of hedgehog signal pathway by cyclopamine attenuates inflammation and articular cartilage damage in rats with adjuvant-induced arthritis

    Journal of Pharmacy and Pharmacology

    Volume 67, Issue 7, July 2015, Pages: 963–971, Rong Li, Li Cai, Jing Ding, Cheng-mu Hu, Ting-ni Wu and Xiang-yang Hu

    Article first published online : 3 FEB 2015, DOI: 10.1111/jphp.12379

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    Hedgehog signaling pathway mediates the progression of non-invasive breast cancer to invasive breast cancer

    Cancer Science

    Volume 102, Issue 2, February 2011, Pages: 373–381, Masae Souzaki, Makoto Kubo, Masaya Kai, Chizu Kameda, Haruo Tanaka, Tomoaki Taguchi, Masao Tanaka, Hideya Onishi and Mitsuo Katano

    Article first published online : 22 NOV 2010, DOI: 10.1111/j.1349-7006.2010.01779.x