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There are 11969 results for: content related to: Pharmacogenetics and pharmacogenomics of anticancer agents

  1. PhRMA White Paper on ADME Pharmacogenomics

    The Journal of Clinical Pharmacology

    Volume 48, Issue 7, July 2008, Pages: 849–889, Dr J. Andrew Williams, Dr Tommy Andersson, Dr Tommy B. Andersson, Dr Rebecca Blanchard, Dr Martin Otto Behm, Dr Nadine Cohen, Dr Timi Edeki, Dr Monique Franc, Dr Kathleen M. Hillgren, Dr Keith J. Johnson, Dr David A. Katz, Dr Mark N. Milton, Dr Bernard P. Murray, Dr Joseph W. Polli, Dr Deb Ricci, Dr Lisa A. Shipley, Dr Subrahmanyam Vangala and Dr Steven A. Wrighton

    Version of Record online : 7 MAR 2013, DOI: 10.1177/0091270008319329

  2. You have full text access to this Open Access content
    Implementing Pharmacogenomics at Your Institution: Establishment and Overcoming Implementation Challenges

    Clinical and Translational Science

    Accepted manuscript online: 23 MAY 2016, Meghan J. Arwood, Supatat Chumnumwat, Larisa H. Cavallari, Edith A. Nutescu and Julio D. Duarte

    DOI: 10.1111/cts.12404

  3. Pharmacogenomics: a systems approach

    Wiley Interdisciplinary Reviews: Systems Biology and Medicine

    Volume 2, Issue 1, January/February 2010, Pages: 3–22, Liewei Wang

    Version of Record online : 23 JUL 2009, DOI: 10.1002/wsbm.42

  4. You have free access to this content
    Implementation of TPMT testing

    British Journal of Clinical Pharmacology

    Volume 77, Issue 4, April 2014, Pages: 704–714, Lynne Lennard

    Version of Record online : 20 MAR 2014, DOI: 10.1111/bcp.12226

  5. Normal thiopurine methyltransferase phenotype testing in a Crohn disease patient with azathioprine induced myelosuppression

    Internal Medicine Journal

    Volume 39, Issue 2, February 2009, Pages: 121–126, M. Leung, 1 I. Piatkov, 2 C. Rochester, 2 S. C. Boyages and 2 R. W. L. Leong 1

    Version of Record online : 31 MAR 2009, DOI: 10.1111/j.1445-5994.2008.01855.x

  6. You have full text access to this OnlineOpen article
    Thiopurine dose intensity and treatment outcome in childhood lymphoblastic leukaemia: the influence of thiopurine methyltransferase pharmacogenetics

    British Journal of Haematology

    Volume 169, Issue 2, April 2015, Pages: 228–240, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 29 NOV 2014, DOI: 10.1111/bjh.13240

  7. Pharmacogenetics of Adverse Drug Reactions

    Stephens' Detection and Evaluation of Adverse Drug Reactions: Principles and Practice, Sixth Edition

    Sudeep P. Pushpakom, Munir Pirmohamed, Pages: 121–156, 2012

    Published Online : 30 JAN 2012, DOI: 10.1002/9780470975053.ch2

  8. Influence of the variable number of tandem repeats located in the promoter region of the thiopurine methyltransferase gene on enzymatic activity

    Clinical Pharmacology & Therapeutics

    Volume 70, Issue 2, August 2001, Pages: 165–174, Sandra Alves, António Amorim, Fátima Ferreira and Maria João Prata

    Version of Record online : 11 AUG 2001, DOI: 10.1067/mcp.2001.117284

  9. Human thiopurine methyltransferase pharmacogenetics: Gene sequence polymorphisms

    Clinical Pharmacology & Therapeutics

    Volume 62, Issue 1, July 1997, Pages: 60–73, Diane Otterness, Carol Szumlanski, Lynne Lennard, Bjørg Klemetsdal, Jarle Aarbakke, Jeong Ok Park-Hah, Heiko Iven, Kjeld Schmiegelow, Earl Branum, John O'Brien and Richard Weinshilboum

    Version of Record online : 14 JUL 1997, DOI: 10.1016/S0009-9236(97)90152-1

  10. You have full text access to this OnlineOpen article
    Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003

    British Journal of Haematology

    Volume 170, Issue 4, August 2015, Pages: 550–558, Lynne Lennard, Cher S. Cartwright, Rachel Wade and Ajay Vora

    Version of Record online : 5 MAY 2015, DOI: 10.1111/bjh.13469

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    Thiopurine methyltransferase activity and its relationship to the occurrence of rejection episodes in paediatric renal transplant recipients treated with azathioprine

    British Journal of Clinical Pharmacology

    Volume 48, Issue 6, December 1999, Pages: 793–800, Dervieux, Médard, Baudouin, Maisin, Zhang, Broly, Loirat and Jacqz-Aigrain

    Version of Record online : 24 DEC 2001, DOI: 10.1046/j.1365-2125.1999.00087.x

  12. The Increasing Complexity of Mercaptopurine Pharmacogenomics

    Clinical Pharmacology & Therapeutics

    Volume 85, Issue 2, February 2009, Pages: 139–141, S Marsh and DJ Van Booven

    Version of Record online : 5 NOV 2008, DOI: 10.1038/clpt.2008.219

  13. Detection of one single mutation predicts thiopurine S-methyltransferase activity in a population of Saami in northern Norway

    Clinical Pharmacology & Therapeutics

    Volume 70, Issue 2, August 2001, Pages: 183–188, Thrina Loennechen, Egil Utsi, Ingeborg Hartz, Roy Lysaa, Hanne Kildalsen and Jarle Aarbakke

    Version of Record online : 11 AUG 2001, DOI: 10.1067/mcp.2001.117445

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    Tracing the Origin of the Most Common Thiopurine Methyltransferase (TPMT) Variants: Preliminary Data from the Patterns of Haplotypic Association with Two CA Repeats

    Annals of Human Genetics

    Volume 68, Issue 4, July 2004, Pages: 313–323, S. Alves, J. Rocha, A. Amorim and M. J. Prata

    Version of Record online : 28 JUN 2004, DOI: 10.1046/j.1529-8817.2004.00104.x

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    Pharmacogenomics – how close/far are we to practising individualized medicine for children?

    British Journal of Clinical Pharmacology

    Volume 79, Issue 3, March 2015, Pages: 419–428, Chor-Wing Sing, Ching-Lung Cheung and Ian C. K. Wong

    Version of Record online : 20 FEB 2015, DOI: 10.1111/bcp.12338

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    Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease

    Alimentary Pharmacology & Therapeutics

    Volume 43, Issue 8, April 2016, Pages: 863–883, W. Moon and E. V. Loftus Jr

    Version of Record online : 14 FEB 2016, DOI: 10.1111/apt.13559

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    The role of pharmacogenetics in cancer therapeutics

    British Journal of Clinical Pharmacology

    Volume 62, Issue 1, July 2006, Pages: 35–46, Wei Peng Yong, Federico Innocenti and Mark J. Ratain

    Version of Record online : 2 FEB 2006, DOI: 10.1111/j.1365-2125.2006.02591.x

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    Thiopurine methyltransferase genotype–phenotype discordance and thiopurine active metabolite formation in childhood acute lymphoblastic leukaemia

    British Journal of Clinical Pharmacology

    Volume 76, Issue 1, July 2013, Pages: 125–136, Lynne Lennard, Cher Suzanne Cartwright, Rachel Wade, Susan M. Richards and Ajay Vora

    Version of Record online : 20 JUN 2013, DOI: 10.1111/bcp.12066

  19. Thiopurine S-methyltransferase gene polymorphism in Japanese patients with autoimmune liver diseases

    Liver International

    Volume 27, Issue 1, February 2007, Pages: 95–100, Akihiro Tamori, Mayumi Shinzaki, Saori Kosaka, Takehiro Hayashi, Shuji Iwai, Masaru Enomoto, Daiki Habu, Hiroki Sakaguchi, Norifumi Kawada, Masayuki Hino, Susumu Shiomi and Shuhei Nishiguchi

    Version of Record online : 6 DEC 2006, DOI: 10.1111/j.1478-3231.2006.01392.x

  20. You have free access to this content
    Azathioprine and 6-mercaptopurine pharmacogenetics and metabolite monitoring in inflammatory bowel disease

    Journal of Gastroenterology and Hepatology

    Volume 20, Issue 8, August 2005, Pages: 1149–1157, RICHARD B GEARRY and MURRAY L BARCLAY

    Version of Record online : 11 MAY 2005, DOI: 10.1111/j.1440-1746.2005.03832.x