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There are 14755 results for: content related to: Molecular Approaches to Chemotherapy and Prevention

  1. You have free access to this content
    MGMT activity, promoter methylation and immunohistochemistry of pretreatment and recurrent malignant gliomas: a comparative study on astrocytoma and glioblastoma

    International Journal of Cancer

    Volume 127, Issue 9, 1 November 2010, Pages: 2106–2118, Markus Christmann, Georg Nagel, Sigrid Horn, Ulrike Krahn, Dorothee Wiewrodt, Clemens Sommer and Bernd Kaina

    Version of Record online : 3 FEB 2010, DOI: 10.1002/ijc.25229

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    O6-methylguanine DNA methyltransferase repairs platinum-DNA adducts following cisplatin treatment and predicts prognoses of nasopharyngeal carcinoma

    International Journal of Cancer

    Volume 137, Issue 6, 15 September 2015, Pages: 1291–1305, Shang Hung Chen, Ching Chuan Kuo, Chien Feng Li, Chun Hei Antonio Cheung, Tsui Chun Tsou, Huai Chih Chiang, Yun Ning Yang, Shin Lun Chang, Li Ching Lin, Hsin Yi Pan, Kwang Yu Chang and Jang Yang Chang

    Version of Record online : 6 MAR 2015, DOI: 10.1002/ijc.29486

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    MGMT in primary and recurrent human glioblastomas after radiation and chemotherapy and comparison with p53 status and clinical outcome

    International Journal of Cancer

    Volume 122, Issue 6, 15 March 2008, Pages: 1391–1399, Dorothee Wiewrodt, Georg Nagel, Nadine Dreimüller, Thomas Hundsberger, Axel Perneczky and Bernd Kaina

    Version of Record online : 13 NOV 2007, DOI: 10.1002/ijc.23219

  4. Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow

    The Journal of Gene Medicine

    Volume 8, Issue 9, September 2006, Pages: 1071–1085, Belinda A. Kramer, Frances A. Lemckert, Ian E. Alexander, Peter W. Gunning and Geoffrey B. McCowage

    Version of Record online : 27 JUN 2006, DOI: 10.1002/jgm.937

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    Activity of O6-methylguanine-DNA methyltransferase in relation to p53 status and therapeutic response in ovarian cancer

    International Journal of Cancer

    Volume 84, Issue 4, 20 August 1999, Pages: 388–395, Jan G. Hengstler, Berno Tanner, Lars Möller, Rolf Meinert and Bernd Kaina

    Version of Record online : 10 NOV 1999, DOI: 10.1002/(SICI)1097-0215(19990820)84:4<388::AID-IJC10>3.0.CO;2-3

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    Predictive impact of MGMT promoter methylation in glioblastoma of the elderly

    International Journal of Cancer

    Volume 131, Issue 6, 15 September 2012, Pages: 1342–1350, Guido Reifenberger, Bettina Hentschel, Jörg Felsberg, Gabriele Schackert, Matthias Simon, Oliver Schnell, Manfred Westphal, Wolfgang Wick, Torsten Pietsch, Markus Loeffler, Michael Weller and for the German Glioma Network

    Version of Record online : 11 JAN 2012, DOI: 10.1002/ijc.27385

  7. Inactivation of O6-methyguanine-DNA methyltransferase by promoter hypermethylation: Association of epithelial ovarian carcinogenesis in specific histological types

    Journal of Obstetrics and Gynaecology Research

    Volume 37, Issue 7, July 2011, Pages: 851–860, Hyun-Jin Roh, Dong-Soo Suh, Kyung-Un Choi, Hang-Jo Yoo, Won-Deok Joo and Man-Soo Yoon

    Version of Record online : 31 MAR 2011, DOI: 10.1111/j.1447-0756.2010.01452.x

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    MGMT CpG island is invariably methylated in adult astrocytic and oligodendroglial tumors with IDH1 or IDH2 mutations

    International Journal of Cancer

    Volume 131, Issue 5, 1 September 2012, Pages: 1104–1113, Shani Mulholland, Danita M. Pearson, Rifat A. Hamoudi, Deborah S. Malley, Caroline M. Smith, Jamie M.J. Weaver, David T.W. Jones, Sylvia Kocialkowski, L. Magnus Bäcklund, V. Peter Collins and Koichi Ichimura

    Version of Record online : 11 JAN 2012, DOI: 10.1002/ijc.26499

  9. Anti-O6-Methylguanine-Methyltransferase (MGMT) Immunohistochemistry in Glioblastoma Multiforme: Observer Variability and Lack of Association with Patient Survival Impede Its Use as Clinical Biomarker

    Brain Pathology

    Volume 18, Issue 4, October 2008, Pages: 520–532, Matthias Preusser, Robert Charles Janzer, Jörg Felsberg, Guido Reifenberger, Marie-France Hamou, Annie-Claire Diserens, Roger Stupp, Thierry Gorlia, Christine Marosi, Harald Heinzl, Johannes A Hainfellner and Monika Hegi

    Version of Record online : 8 APR 2008, DOI: 10.1111/j.1750-3639.2008.00153.x

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    Acquired resistance of melanoma cells to the antineoplastic agent fotemustine is caused by reactivation of the DNA repair gene mgmt

    International Journal of Cancer

    Volume 92, Issue 1, 1 April 2001, Pages: 123–129, Markus Christmann, Matthias Pick, Hermann Lage, Dirk Schadendorf and Bernd Kaina

    Version of Record online : 7 FEB 2001, DOI: 10.1002/1097-0215(200102)9999:9999<::AID-IJC1160>3.0.CO;2-V

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    Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol

    International Journal of Cancer

    Volume 118, Issue 3, 1 February 2006, Pages: 527–531, Rana Abdel-Fattah, Adam Glick, Ishtiaq Rehman, Patrick Maiberger and Henry Hennings

    Version of Record online : 10 AUG 2005, DOI: 10.1002/ijc.21316

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    Promoter hypermethylation of MGMT is associated with protein loss in gastric carcinoma

    International Journal of Cancer

    Volume 93, Issue 6, 15 September 2001, Pages: 805–809, Naohide Oue, Hideo Shigeishi, Hiroki Kuniyasu, Hiroshi Yokozaki, Kazuya Kuraoka, Reiko Ito and Wataru Yasui

    Version of Record online : 13 JUN 2001, DOI: 10.1002/ijc.1403

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    Methylation pattern of the O6-methylguanine-DNA methyltransferase gene in colon during progressive colorectal tumorigenesis

    International Journal of Cancer

    Volume 122, Issue 11, 1 June 2008, Pages: 2429–2436, Takeshi Nagasaka, Ajay Goel, Kenji Notohara, Takaomi Takahata, Hiromi Sasamoto, Takuyuki Uchida, Naoshi Nishida, Noriaki Tanaka, Clement Richard Boland and Nagahide Matsubara

    Version of Record online : 31 JAN 2008, DOI: 10.1002/ijc.23398

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    Tamoxifen accelerates proteasomal degradation of O6-methylguanine DNA methyltransferase in human cancer cells

    International Journal of Cancer

    Volume 121, Issue 10, 15 November 2007, Pages: 2293–2300, Ching-Chuan Kuo, Jin-Fen Liu, Her-Shyong Shiah, Li-Chen Ma and Jang-Yang Chang

    Version of Record online : 27 JUN 2007, DOI: 10.1002/ijc.22927

  15. DNA repair gene O6-methylguanine-DNA methyltransferase: Promoter hypermethylation associated with decreased expression and G:C to A:T mutations of p53 in brain tumors

    Molecular Carcinogenesis

    Volume 36, Issue 1, January 2003, Pages: 23–31, Dong Yin, Dong Xie, Wolf-Karsten Hofmann, Wenxuan Zhang, Kamlesh Asotra, Rex Wong, Keith L Black and H. Phillip Koeffler

    Version of Record online : 26 DEC 2002, DOI: 10.1002/mc.10094

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    Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas

    International Journal of Cancer

    Volume 129, Issue 3, 1 August 2011, Pages: 659–670, Jörg Felsberg, Niklas Thon, Sabina Eigenbrod, Bettina Hentschel, Michael C. Sabel, Manfred Westphal, Gabriele Schackert, Friedrich Wilhelm Kreth, Torsten Pietsch, Markus Löffler, Michael Weller, Guido Reifenberger, Jörg C. Tonn and for the German Glioma Network

    Version of Record online : 26 MAY 2011, DOI: 10.1002/ijc.26083

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    O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation and low MGMT-encoded protein expression as prognostic markers in glioblastoma patients treated with biodegradable carmustine wafer implants after initial surgery followed by radiotherapy with concomitant and adjuvant temozolomide

    Cancer

    Volume 118, Issue 18, 15 September 2012, Pages: 4545–4554, Emmanuèle Lechapt-Zalcman, Guénaëlle Levallet, Audrey Emmanuelle Dugué, Anne Vital, Marie-Danièle Diebold, Philippe Menei, Philippe Colin, Philippe Peruzzy, Evelyne Emery, Myriam Bernaudin, Françoise Chapon and Jean-Sébastien Guillamo

    Version of Record online : 22 FEB 2012, DOI: 10.1002/cncr.27441

  18. MGMT promoter methylation correlates with survival benefit and sensitivity to temozolomide in pediatric glioblastoma

    Pediatric Blood & Cancer

    Volume 48, Issue 4, April 2007, Pages: 403–407, Andrew M. Donson, Steven O. Addo-Yobo, Michael H. Handler, Lia Gore and Nicholas K. Foreman

    Version of Record online : 11 APR 2006, DOI: 10.1002/pbc.20803

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    Aggressive pituitary tumours: the role of temozolomide and the assessment of MGMT status

    European Journal of Clinical Investigation

    Volume 41, Issue 10, October 2011, Pages: 1133–1148, Ann I. McCormack, John A. H. Wass and Ashley B. Grossman

    Version of Record online : 18 APR 2011, DOI: 10.1111/j.1365-2362.2011.02520.x

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    Methylguanine DNA Methyltransferase-Mediated Drug Resistance-Based Selective Enrichment and Engraftment of Transplanted Stem Cells in Skeletal Muscle

    STEM CELLS

    Volume 27, Issue 5, May 2009, Pages: 1098–1108, Antonio S. J. Lee, Prathibha Kahatapitiya, Belinda Kramer, Josephine E. Joya, Jeff Hook, Renjing Liu, Galina Schevzov, Ian E. Alexander, Geoff McCowage, Didier Montarras, Peter W. Gunning and Edna C. Hardeman

    Version of Record online : 5 FEB 2009, DOI: 10.1002/stem.28