Genomics, Proteomics and Vaccines

Genomics, Proteomics and Vaccines

Editor(s): Guido Grandi

Published Online: 28 JAN 2005

Print ISBN: 9780470856161

Online ISBN: 9780470012536

DOI: 10.1002/0470012536

About this Book

While the sequence of the human genome sequence has hit the headlines, extensive exploitation of this for practical applications is still to come. Genomic and post-genomic technologies applied to viral and bacterial pathogens, which are almost equally important from a scientific perspective, have the potential to be translated into useful products and processes much more rapidly.

Genomics, Proteomics and Vaccines introduces the history of vaccinology and discusses how vaccines are expected to evolve in the future. It describes the relevant technologies, including genome sequencing and analysis, DNA microarrays, 2D electrophoresis and 2D chromatography, mass spectrometry and high-throughput protein expression and purification. The book also features examples of the exploitation of genomics and post-genomics in vaccine discovery, and contains useful descriptions of the biology and pathogenesis of clinically important bacterial pathogens.

This book should be of interest to all those working in vaccine discovery and development in pharmaceutical and biotechnology companies as well as in academic institutions

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Part 1: Introduction

  2. Part 2: Technologies

    1. Chapter 5

      The Proteome, Anno Domini Two Zero Zero Three (pages 103–134)

      Pier Giorgio Righetti, Mahmoud Hamdan, Frederic Reymond and Joël S. Rossier

  3. Part 3: Applications

    1. Chapter 9

      Vaccines against Pathogenic Streptococci (pages 205–222)

      John L. Telford, Immaculada Margarit Y Ros, Domenico Maione, Vega Masignani, Hervé Tettelin, Giuliano Bensi and Guido Grandi

    2. Chapter 12

      Proteomics and Anti-Chlamydia Vaccine Discovery (pages 267–283)

      Gunna Christiansen, Svend Birkelund, Brian B. Vandahl and Allan C Shaw

    1. You have free access to this content