eLS

Copyright © 1999-2014 by John Wiley and Sons, Inc. All Rights Reserved.

eLS

Online ISBN: 9780470015902

DOI: 10.1002/047001590X

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  1. Biochemistry
  2. Bioethics & Philosophy
  3. Cell Biology
  4. Developmental Biology
  5. Ecology
  6. Evolution & Diversity of Life
  7. Genetics & Disease
  8. Immunology
  9. Microbiology
  10. Molecular Biology
  11. Neuroscience
  12. Plant Science
  13. Science & Society
  14. Structural Biology
    1. Bioinformatics
    2. Cell Motility and Transport
    3. Electron Microscopy
    4. General Structural Biology
    5. Lipids and Membrane Structure
    6. Mass Spectrometry
    7. Membrane Proteins
    8. Nuclear Magnetic Resonance
    9. Nucleic Acid Structure
    10. Optical Microscopy
    11. Protein Folding, Evolution and Degradation
    12. Protein Structure
      1. Actin and Actin Filaments
      2. Amidohydrolase Superfamily
      3. Amino Acid Side-chain Hydrophobicity
      4. Amino Acid Substitutions: Effects on Protein Stability
      5. γ-Aminobutyric Acid (GABA) Receptors
      6. AMPA Receptors
      7. Amyloid State of Proteins in Human Disease
      8. Amyloidosis
      9. Antibody Classes
      10. Antigen–Antibody Binding
      11. Antitrypsin (AAT) Deficiency-α1
      12. Archaeal Ribosomes
      13. ATP-binding Motifs
      14. Automated Protein Production Technologies
      15. Baculovirus Expression Strategies for Protein Complex Production
      16. Biological Macromolecules: UV-visible Spectrophotometry
      17. Biotin
      18. BLAST Algorithm
      19. Blood Group Genetics
      20. CAD: A Multifunctional Protein Leading De Novo Pyrimidine Biosynthesis
      21. Calcium-Binding Proteins
      22. Caspases and Cell Death
      23. Caspases, Substrates and Sequential Activation
      24. Catalysis of Disulfide Bond Formation by the Quiescin Sulfhydryl Oxidases
      25. Cell Locomotion
      26. Chaperonins
      27. Chlorophyll-Binding Proteins
      28. Chlorophyll: Structure and Function
      29. Chromatin Recognition Protein Modules: The PHD Finger
      30. Chromatin Remodelling and Histone Modification in Transcription Regulation
      31. Chromatin Structure and Domains
      32. Chromosomal Bands and Sequence Features
      33. Chromosomes: Nonhistone Proteins
      34. Cilia and Flagella
      35. Circular Dichroism: Studies of Proteins
      36. Cobalamin Coenzymes and Vitamin B12
      37. Coenzymes: Haem
      38. Complement: Terminal Pathways
      39. Cryogenic Detectors: Detection of Single Molecules
      40. Crystallins
      41. Crystallisation of Proteins and Macromolecular Complexes: Past, Present and Future
      42. Crystallization of Protein–DNA Complexes
      43. Cystatins
      44. Cytoskeleton
      45. Cytoskeleton Dynamics: Actin in Cell Invasion
      46. Deafness
      47. Death Receptors at the Molecular Level: Therapeutic Implications
      48. Difference Gel Electrophoresis (DIGE)
      49. Disordered Proteins
      50. Disulfide Bonds
      51. DNA Helicases
      52. DNA Methylation
      53. You have free access to this content
        DNA Replication
      54. DNA-binding Enzymes: Structural Themes
      55. Dynamic Programming
      56. Dynein and Kinesin
      57. EF-Hand Calcium-Binding Proteins
      58. Electron Cryomicroscopy and Three-dimensional Computer Reconstruction of Biological Molecules
      59. Electron Paramagnetic Resonance (EPR) and Spin-labelling
      60. EM Analysis of Protein Structure
      61. Engineered Enzymes
      62. Enzyme Activity: Allosteric Regulation
      63. Enzyme Activity: Control
      64. Enzyme Specificity and Selectivity
      65. Enzymes: Phosphopantetheine-dependent
      66. Enzymes: The Active Site
      67. Epitope Mapping: B-cell Epitopes
      68. Erythrocyte Membrane Disorders
      69. Eukaryotic Replication Fork
      70. Eukaryotic Replication Protein A
      71. Evolution of Protein Domains
      72. Exosome Complex
      73. Expression Tags for Protein Production
      74. Fc Receptors
      75. Fibrinogen and Fibrin
      76. Flavoenzymes: Covalent versus Noncovalent
      77. Forkhead Domains
      78. From Reactive Oxygen and Nitrogen Species to Therapy
      79. Fusion Proteins as Research Tools
      80. G Protein-Coupled Receptors
      81. G Proteins
      82. Gel-Staining Techniques – Dyeing to Know It All
      83. Genome, Proteome and the Quest for a Full Structure–Function Description of an Organism
      84. Global Alignment
      85. Globin Genes: Polymorphic Variants and Mutations
      86. Glycoproteins
      87. Glycosidases: Functions, Families and Folds
      88. Glycosylation and Disease
      89. Green Fluorescent Protein (GFP)
      90. GTP-binding Loop
      91. Haem Proteins
      92. Haem Structure and Function
      93. Haemoglobin: Cooperativity in Protein–Ligand Interactions
      94. Hidden Markov Models
      95. Histones: Gene Organisation and Post-translational Modification
      96. History of Protein Chemistry
      97. Hsp110 Chaperones
      98. Hsp90 Chaperones
      99. Hydrogen Bonds in Proteins: Role and Strength
      100. Hydrophobicity Plots
      101. Identification of Protein–Protein Interactions
      102. Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily
      103. Immunoglobulin Superfamily
      104. Industrialization of Proteomics: Scaling UpProteomics Processes
      105. Inhibitor of Apoptosis (IAP) and BIR-containing Proteins
      106. Integrase Class Site-specific Recombinases
      107. Integrins
      108. Interaction Networks of Proteins
      109. Intrinsically Disordered Proteins
      110. Iron–Sulfur Proteins: Structure, Function and Biogenesis
      111. Laser Capture Microdissection in Proteomics
      112. Lectins
      113. Leucine Zipper
      114. Leucine Zippers
      115. Light-harvesting Complex
      116. Limits of Proteomics: Protein Solubilisation Issues
      117. Lipoprotein Metabolism: Structure and Function
      118. Luciferases and Light-emitting Accessory Proteins: Structural Biology
      119. Macromolecular Interactions: Light Scattering
      120. Macromolecular Structure Determination by X-ray Crystallography
      121. Major Histocompatibility Complex (MHC) Genes
      122. Major Histocompatibility Complex: Interaction with Peptides
      123. Mass Spectrometry in Protein Characterization
      124. Mass Spectrometry Instrumentation in Proteomics
      125. Mass Spectrometry: Analysis of Two-Dimensional Protein Gels
      126. Mass Spectrometry: Peptide Sequencing
      127. Membrane Insertion of Tail-anchored Proteins
      128. You have free access to this content
        Messenger RNA: Interaction with Ribosomes
      129. Metalloenzymes and Electrophilic Catalysis
      130. Microtubule Plus-End-Tracking Proteins
      131. Molecular Dynamics
      132. Molecular Entry Point: Strategies in Proteomics
      133. Molecular Genetics of the α-Thalassaemias
      134. Molecular Genetics of the Fibrillinopathies
      135. Molecular Imaging in Genomic Medicine
      136. Molecular Machines and Human Disorders
      137. Molten Globule
      138. Motor Proteins
      139. Multidomain Proteins
      140. Multiple Alignment
      141. Myoglobin
      142. Myosin Superfamily
      143. NAD(P)+ Binding to Dehydrogenases
      144. Nitrogenase Complex
      145. NMR Spectroscopy for Monitoring Functional Dynamics in Solution
      146. Non-Classical MHC Class I Molecules (MHC-Ib)
      147. Nuclear Magnetic Resonance (NMR) of Proteins: Solid State
      148. Nuclear Magnetic Resonance (NMR) Spectroscopy of Proteins
      149. Nucleolar Proteomics
      150. Nucleolus: Structure and Function
      151. Nucleosomes: Detailed Structure and Mutations
      152. Nucleosomes: Structure and Function
      153. Olfactory Receptors
      154. Pattern Searches in Protein Sequences
      155. Peptidases
      156. Peptide Bonds, Disulfide Bonds and Properties of Small Peptides
      157. Peptide Mapping
      158. Peptide Sequencing by Edman Degradation
      159. Peptides: Biological Activities of Small Peptides
      160. Peptidyl Prolyl cis/trans Isomerases
      161. Phosphoproteomics
      162. Photosystem I
      163. Plant Storage Products (Carbohydrates, Oils and Proteins)
      164. Posttranslational Modification and Human Disorders
      165. Posttranslational Modifications in Plant Disease Resistance
      166. Posttranslational Processing: Peptide Hormones and Neuropeptide Transmitters
      167. Potassium Channels
      168. Preparation Artefacts in Proteomics: Technological Issues
      169. Primary Protein and Nucleic Acid Three-dimensional Structure Databases
      170. Prions
      171. Prions
      172. Profile Searching
      173. Proline Residues in Proteins
      174. Protease Complexes
      175. Protein Coding
      176. Protein Databases: Operations, Possibilities and Challenges
      177. Protein Design
      178. Protein Disorder and Human Genetic Disease
      179. Protein Disulfide Isomerases
      180. Protein Domain Fusion
      181. Protein Families: Evolution
      182. Protein Folding: Overview of Pathways
      183. Protein Homology Modelling
      184. Protein Interaction and Genetic Disease
      185. Protein Isoforms and Isozymes
      186. Protein Motifs for DNA Binding
      187. Protein Motifs: the Helix-Loop-Helix Motif
      188. Protein Motifs: the Helix-Turn-Helix Motif
      189. Protein Motifs: Zinc Fingers
      190. Protein Phosphatases
      191. Protein Primary Structure
      192. Protein Quaternary Structure: Subunit–Subunit Interactions
      193. Protein Quaternary Structure: Symmetry Patterns
      194. Protein Secondary Structures: Prediction
      195. Protein Sequence Databases
      196. Protein Stability
      197. Protein Structural Flexibility: Molecular Motions
      198. Protein Structure
      199. Protein Structure and Interactions from Nuclear Magnetic Resonance Spectroscopy
      200. Protein Structure Classification
      201. Protein Structure Design and Engineering
      202. Protein Structure Prediction
      203. Protein Structure Prediction and Databases
      204. Protein Structure: Unusual Covalent Bonds
      205. Protein Superfamilies
      206. Protein Synthesis: Measuring Errors
      207. Protein Tertiary Structures: Prediction from Amino Acid Sequences
      208. Protein–DNA Complexes: Nonspecific
      209. Protein–DNA Complexes: Specific
      210. Protein–DNA Interactions: Polyelectrolyte Effects
      211. Protein–DNA Interactions: Structure and Energetics
      212. Protein–DNA Interactions: Techniques Used
      213. Protein–Ligand Interactions: Computational Docking
      214. Protein–Ligand Interactions: Energetic Contributions and Shape Complementarity
      215. Protein–Ligand Interactions: General Description
      216. Protein–Ligand Interactions: Induced Fit
      217. Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants
      218. Protein–protein Interactions: Identification
      219. Protein–RNA Interactions
      220. Proteins: Affinity Tags
      221. Proteins: Fundamental Chemical Properties
      222. Proteins: Mutational Effects in
      223. Proteins: Postsynthetic Modification – Function and Physical Analysis
      224. Proteoglycans
      225. Proteomics: A Molecular Scanner in Medicine
      226. Purifying and Analysing Cytosolic Protein Complexes
      227. Pyruvate Dehydrogenase Complex
      228. Quantitative Proteomics (ICAT™)
      229. Rad51 and Eukaryotic Recombination Proteins
      230. Radical Enzymes
      231. Radical S-Adenosylmethionine (SAM) Superfamily
      232. RecA Protein
      233. RecFOR Protein
      234. Regulation by Covalent Modification
      235. Resonance Raman Spectroscopy
      236. Rhodopsin
      237. Ribosomal Proteins in Eukaryotes
      238. Ribosomal Proteins: Structure and Evolution
      239. Ribosomal RNA
      240. Ribosomes and Ribosomal Proteins: More Than Just ‘Housekeeping’
      241. RNA Polymerase II Holoenzyme and Transcription Factors
      242. RNA Polymerases: Subunits and Functional Domains
      243. RNA Synthesis
      244. Role of Nonmotor Microtubule-Associated Proteins in Mitotic Spindle Assembly
      245. Selenocysteine
      246. Sequence Alignment
      247. Sequence Similarity
      248. Serine Proteases
      249. Signal Peptides
      250. Single-stranded DNA-binding Proteins
      251. Small-Angle Scattering of Neutrons and X-Rays
      252. Smith–Waterman Algorithm
      253. Structural Basis of Disulfide Bond Formation in the Bacterial Periplasm and Mammalian ER
      254. Structural Databases of Biological Macromolecules
      255. Structural Genomics
      256. Structural Predictions and Modeling
      257. Structural Proteomics: Large-Scale Studies
      258. Structure and Function of IAP and Bcl-2 Proteins
      259. Structure–Function Relationships in the Aromatic Amino Acid Hydroxylases Enzyme Family: Evolutionary Insights
      260. Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD)
      261. SUMOylation
      262. Synaptic Vesicle Proteins
      263. Tandem Affinity Purification (TAP) Tags
      264. Tay–Sachs Disease
      265. Telomeres: Protection and Maintenance
      266. Thalassemias
      267. Thermosome: A Group II Chaperonin of Archaea
      268. Thiamin Diphosphate and Vitamin B1
      269. Tissue-specific Locus Control: Structure and Function
      270. Titin Gene (TTN)
      271. Transcription Activation in Eukaryotic Cells
      272. The Transcription/DNA Repair Factor TFIIH
      273. Transition States: Substrate-induced Conformational Transitions
      274. Translation of mRNAs in Xenopus Oocytes
      275. Transmembrane Domains
      276. Tubulin and FtsZ Superfamily of Protein Assembly Machines
      277. Tubulin and Microtubules
      278. Two-Component Signalling in Plants
      279. Two-Dimensional Crystallisation of Membrane Proteins and Structural Assessment
      280. Two-dimensional Electron Crystallography
      281. Two-dimensional Gel Electrophoresis
      282. Ubiquitin Pathway
      283. Vitamin K: Structure and Function
      284. Zinc-finger Genes
    13. Replication and Recombination
    14. Sample Preparation in Structural Biology
    15. Signal Transduction
    16. Single Molecule Analysis
    17. Spectrophotometric Methods
    18. Structure of Cell-Cell Interactions
    19. Transcription
    20. Translation and Protein synthesis
    21. Virus Structure and Function
    22. X-Ray Crystallography
  15. Virology

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