Online ISBN: 9780470015902

DOI: 10.1002/047001590X

Browse by Topic

  1. Antibodies
  2. Biochemistry
  3. Bioethics & Philosophy
  4. Biomolecular Interactions
  5. Cell Biology
  6. Developmental Biology
  7. Diagnostics, Therapeutics and Methods
  8. Ecology
  9. Enzymes: Structure and Action Mechanism
  10. Evolution & Diversity of Life
  11. Genetics & Disease
    1. Bioinformatics and Genetic Disease
    2. Cancer Genetics
      1. Aberrant DNA Methylation and Histone Modifications in Cancer
      2. Advances in Next Generation Sequencing Technologies and Cancer Epigenomics
      3. Alterations in DNA Methylation Resulting from Exposure to Chemical Carcinogens
      4. Analysis of Somatic Mutations in Cancer Tissues Challenges the Somatic Mutation Theory of Cancer
      5. Aneuploidy and Protein Homeostatic Imbalance
      6. Apoptosis and the Cell Cycle in Human Disease
      7. Assessing Genetic Variants of Uncertain Significance: The Example of Breast Cancer
      8. Assessing Genetic Variants of Uncertain Significance: The Example of Lynch Syndrome
      9. Barrett Esophagus
      10. The BCL-2 Family Proteins – Key Regulators and Effectors of Apoptosis
      11. Biallelic Germline Mutations of Mismatch-Repair Genes and Paediatric Malignancies
      12. Bladder Cancer
      13. Brain Cancers
      14. Brain Tumours
      15. Breast Cancer
      16. Breast Cancer Susceptibility Genes
      17. Cancer
      18. Cancer and the Ageing Process
      19. Cancer Cytogenetics
      20. Cancer Evolution
      21. Cancer Genome Anatomy Project
      22. Cancer Genome Sequencing
      23. Cancer Systems Biology: Current Achievements in – Omics Data Analysis, Network Reconstruction and Mathematical Modelling
      24. Cancer: Chromosomal Abnormalities
      25. Caretakers and Gatekeepers
      26. Causes and Consequences of Structural Genomic Alterations in the Human Genome
      27. You have free access to this content
        Cell Cycle Checkpoint Genes and Cancer
      28. Characterising Somatic Mutations in Cancer Genome by Means of Next-generation Sequencing
      29. Chromosomal Instability (CIN) in Cancer
      30. Chromosome Instability (CIN), Aneuploidy and Cancer
      31. Chromosome Rearrangements
      32. Chromothripsis and Human Genetic Disease
      33. Chronic Myeloid Leukaemia
      34. Chronic Myeloproliferative Neoplasms: Clinical and Molecular Genetics
      35. Clinical Molecular Cytogenetics
      36. Clustered Mutations in Human Cancer
      37. Colon Cancer
      38. You have free access to this content
        Colorectal Cancer: Genetics
      39. Computational Prediction of Genetic Drivers in Cancer
      40. Cytogenetic and Physical Chromosomal Maps: Integration
      41. De Novo Methylation in Cancer
      42. Developmental Syndromes of Ras/MAPK Pathway Dysregulation
      43. DNA Damage Response: From Tumourigenesis to Therapy
      44. DNA Interstrand Crosslink Repair
      45. DNA Methylation and Histone Acetylation
      46. DNA Methylation and Mutation
      47. DNA Repair: Disorders
      48. Endometrial Cancer
      49. Environmental Carcinogens and Mutagens
      50. Epigenetic Drivers of Genetic Alterations in Cancer
      51. Epigenetic Mechanisms in Lynch Syndrome
      52. Epimutations and Cancer Susceptibility
      53. Familial Adenomatous Polyposis
      54. Familial Breast Cancer: Genetic Testing
      55. Fusion Proteins and Diseases
      56. Gain-of-Function Mutants of p53 and Their Role in Tumourigenesis
      57. Gain-of-function Mutations in Human Genetic Disorders
      58. GAS5 Gene
      59. Gastric Cancer
      60. Gene Amplification and Cancer
      61. Genetic and Epigenetic Heterogeneity in Cancer
      62. Genetic Risk
      63. Genetic Susceptibility to Triple-Negative Breast Cancers
      64. Genetic Variants Involved in Intracellular Mechanisms of Chemoresistance to Anticancer Drugs Due to Changes in the Effect on Their Molecular Targets
      65. Genetics and Genomics of Malignant Rhabdoid Tumours
      66. Genetics of Carney Complex
      67. Genetics of Congenital Tooth Agenesis
      68. Genetics of Pheochromocytoma
      69. Genetics of PTEN Hamartoma Tumour Syndrome
      70. Genetics of Susceptibility to Sporadic Ovarian Cancer
      71. Genome-wide Association Studies of Cancers
      72. Genomic and Chromosomal Instability
      73. Genotoxicity and Epigenetic Modifications in Response to Atmospheric and Engineered Nanoparticles
      74. Germline Copy Number Variation and Cancer Risk
      75. Germline Genomic Copy Number Variation Contribution to Cancer Predisposition
      76. Hamartomatous Polyposis Syndromes: Peutz–Jeghers Syndrome and Familial Juvenile Polyposis
      77. Hepatocellular Carcinoma
      78. Hereditary Breast Cancer Syndromes: Molecular Pathogenesis and Diagnostics
      79. Hereditary Nonpolyposis Colorectal Cancer
      80. Histidine Triad (HIT) Superfamily
      81. Histone Acetylation and Disease
      82. History of Cancer Research
      83. Human Intronless Genes and their Associated Diseases
      84. Human Mismatch Repair: Defects and Predisposition to Cancer
      85. Human Topoisomerase I Inhibitors
      86. Identifying New Targets for Personalised Cancer Therapy
      87. Implications of RNA-binding Proteins for Human Diseases
      88. Importance of Mutation Analysis in Anti-Cancer Therapy
      89. Interpreting Disease Relevance of Amino Acid Substitutions
      90. JAK/STAT Signalling and Haematological Malignancies
      91. Kinases and Phosphatases and Human Disorders: The First Drugs
      92. Leukaemias and Lymphomas
      93. Leukemias and Lymphomas: Genetics
      94. Li–Fraumeni Syndrome
      95. Long Noncoding RNAs and Cancer
      96. Long Noncoding RNAs and Tumorigenesis
      97. Loss of Heterozygosity
      98. Lung Cancer: Genetics
      99. Melanoma
      100. Melanoma: Genetics
      101. Methylation-mediated Transcriptional Silencing in Tumorigenesis
      102. Microarrays and Expression Profiling in Cancer
      103. Microarrays in Disease Diagnosis and Prognosis
      104. MicroRNA Signatures as Biomarkers in Cancer
      105. MicroRNAs and Their Role in Cancer
      106. MicroRNAs in Cancer
      107. Mitochondrial DNA Copy Number Alterations in Human Cancers
      108. Mitosis: Chromosome Segregation and Stability
      109. Molecular Biology of Breast Cancer
      110. Molecular Cytogenetic Analysis: Applications in Cancer
      111. Molecular Genetics in Acromegaly
      112. Molecular Genetics of Chronic Lymphocytic Leukaemia
      113. The Molecular Genetics of Corticotroph Tumours
      114. Molecular Genetics of Ewing Sarcoma
      115. Molecular Genetics of Gallbladder Cancer
      116. Molecular Genetics of Malignant Mesothelioma
      117. Molecular Genetics of Mantle Cell Lymphoma
      118. Molecular Genetics of Medulloblastoma
      119. Molecular Genetics of Meningioma
      120. Molecular Genetics of Metastasis
      121. Molecular Genetics of Multiple Myeloma
      122. Molecular Genetics of Multiple Osteochondromas
      123. Molecular Genetics of MUTYH-Associated Polyposis
      124. Molecular Genetics of Myeloproliferative Disorders
      125. Molecular Genetics of Nasopharyngeal Carcinoma
      126. Molecular Genetics of Oral Cancer
      127. Molecular Genetics of Pancreatic Endocrine Tumours
      128. Molecular Genetics of Peripheral T-cell Lymphomas
      129. Molecular Genetics of Renal Cancer
      130. Molecular Genetics of Rhabdomyosarcoma
      131. The Molecular Genetics of Schwannomatosis
      132. Multidrug Resistance in Cancer: Genetics of ABC Transporters
      133. Multiple Endocrine Neoplasia Type 2
      134. Multiple Endocrine Neoplasias
      135. Mutation Detection
      136. Neuroblastoma
      137. Neurofibromatosis Type 2 Clinics and Genetics
      138. Neurofibromatosis Type I (NF1)
      139. Nevoid Basal Cell Carcinoma (Gorlin) Syndrome
      140. Next-Generation Sequencing in Cancer: Tools for Fusion Gene Detection
      141. Non-Hodgkin Lymphomas
      142. Notch Signalling in Cancer
      143. NSD1, EZH2 and DNMT3A Overgrowth Genes and Their Associated Overgrowth Syndromes
      144. Oncogenes
      145. You have free access to this content
      146. Oncogenic Kinases in Cancer
      147. Oncogenic Transcription Factors: Target Genes
      148. Osteosarcoma: Genetics of Inherited Susceptibility
      149. P53 and Cell Death
      150. Pancreatic Cancer: Molecular Genetics and Clinical Applications
      151. Personalised Cancer Medicine: Fulfilling the Promise
      152. Pituitary Gene Signalling Pathway
      153. Prostate Cancer
      154. Prostate Cancer
      155. Protein Kinases in the Era of Precision Medicine
      156. Ras Mutations in Cancer
      157. Regulation and Function of the MYC Oncogene
      158. Renal Carcinoma and von Hippel–Lindau Disease
      159. Repetitive Elements and Human Disorders
      160. Retinoblastoma
      161. RNA Editing and Human Disorders
      162. Role of Endogenous Retroviruses in Human Genetic Diseases
      163. Role of Polymorphisms in Cancer Susceptibility
      164. Role of the JAK-STAT Signalling Pathway in Cancer
      165. Role of the Wnt Signalling Pathway in Cancer
      166. Somatic Genome Variations
      167. Somatic Mutations in Polycythaemia Vera and Other Philadelphia Chromosome Negative Myeloproliferative Neoplasms
      168. SWI/SNF Chromatin Remodelling and Human Cancer
      169. Syndromes and Diseases Associated with the Notch Signalling Pathway
      170. Technological Advances in the Detection of Novel Fusion Genes
      171. Telomerase: Structure and Function
      172. Telomere Dysfunction in Human Genetic Disease
      173. Telomeres and Telomerase in Ageing and Cancer
      174. Telomeres: Protection and Maintenance
      175. Testicular Cancer
      176. TGF-β Signalling and Its Role in Cancer Progression and Metastasis
      177. The MERTK Signalling Pathway in Cancer
      178. Therapeutic Applications of RNA Interference
      179. Thymidylate Synthesis
      180. Thyroid Cancer: Molecular Genetics
      181. Translocation Breakpoints in Cancer
      182. Transposons in Eukaryotes (Part B): Genomic Consequences of Transposition
      183. Tuberous Sclerosis: Genetics
      184. You have free access to this content
        Tumor Suppressor Genes
      185. Tumour Formation: Number of Mutations Required
      186. Tumour Suppressor Genes
      187. Tumours: Immunotherapy
      188. Understanding Tumour Metabolic Reprogramming with Metabolomics
      189. Uniparental Disomy in Cancer – A New Tool in Molecular Cancer
      190. Wilms Tumor
    3. Chromosomal Disorders
    4. Epigenetics and Disease
    5. Forensic Genetics
    6. Gene and Genome Structure and Organisation
    7. Gene Expression Profiling of Genetic Disease
    8. Gene Mapping by Disease Association
    9. Gene Therapy
    10. General Genetics and Disease
    11. Genetic Counseling
    12. Genetic Models
    13. Genetics of Intelligence and Cognition
    14. Genomic Disorders
    15. Inter-Individual Variation and Polymorphism
    16. Linkage Analysis
    17. Mitochondrial Diseases
    18. Model Organisms and Human Disease
    19. Molecular Genetics of Common and Complex Disease
    20. Mutational Mechanisms of Genetic Disease
    21. Pharmacogenetics and Pharmacogenomics
    22. Proteomic Studies of Genetic Disease
    23. Quantitative Genetics
    24. Specific Genetic Disorders
    25. Statistical Methodology in Genetics
    26. Techniques and Tools in Clinical Genetics
  12. Immunology
  13. Microbiology
  14. Molecular Biology
  15. Neuroscience
  16. Plant Science
  17. Sample Preparation in Structural Biology
  18. Science & Society
  19. Structural Biology
  20. Techniques and Tools in Molecular Biology
  21. Techniques in Cell Biology
  22. Virology