Online ISBN: 9780470015902

DOI: 10.1002/047001590X

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  1. Antibodies
  2. Biochemistry
  3. Bioethics & Philosophy
  4. Biomolecular Interactions
  5. Cell Biology
  6. Developmental Biology
  7. Diagnostics, Therapeutics and Methods
  8. Ecology
  9. Enzymes: Structure and Action Mechanism
  10. Evolution & Diversity of Life
  11. Genetics & Disease
  12. Immunology
  13. Microbiology
  14. Molecular Biology
    1. Chromosomes and Chromatin Modifications
      1. 22q11 Deletion Syndrome: A Role for Tbx1 in Pharynx and Cardiovascular Development
      2. Aberrant DNA Methylation and Histone Modifications in Cancer
      3. Activating and Inactivating Mutations in the GNAS1 Gene
      4. Adaptive Evolution of Centromeric Proteins
      5. Advances in Next Generation Sequencing Technologies and Cancer Epigenomics
      6. Ageing
      7. Ageing Genes: Gerontogenes
      8. Alterations in DNA Methylation Resulting from Exposure to Chemical Carcinogens
      9. Alternative Splicing in the Human Genome and its Evolutionary Consequences
      10. Artificial Chromosomes
      11. Artificial Chromosomes
      12. Bacterial Chromosome
      13. Bacterial Restriction–Modification Systems
      14. Banding Techniques
      15. Base Flipping
      16. Behavioural Genetics in the Postgenomics Era
      17. Biological Complexity: Beyond the Genome
      18. Blocks of Limited Haplotype Diversity
      19. Breast Cancer
      20. Cancer
      21. Cancer Cytogenetics
      22. Cancer Genome Anatomy Project
      23. Cancer: Chromosomal Abnormalities
      24. Cell Cycle
      25. Cell Cycle: Chromosomal Organization
      26. Cell Nucleus
      27. Centromeres
      28. Centromeres
      29. Checkpoints in the Cell Cycle
      30. Chromatin Diminution
      31. Chromatin Recognition Protein Modules: The PHD Finger
      32. Chromatin Remodelling and Histone Modification in Transcription Regulation
      33. Chromatin Structure and Domains
      34. Chromatin Structure and Human Genome Evolution
      35. Chromatin Structure and Modification: Defects
      36. Chromosomal Bands and Sequence Features
      37. Chromosomal Genetic Disease: Structural Aberrations
      38. Chromosomal Rearrangements in the Human and Chimpanzee Lineages
      39. Chromosome
      40. Chromosome Analysis and Identification
      41. Chromosome Condensation and Cohesion
      42. Chromosome Function: Sex Differences
      43. Chromosome Instability (CIN), Aneuploidy and Cancer
      44. Chromosome Mechanics
      45. Chromosome Preparation
      46. You have free access to this content
        Chromosome Preparation and Banding
      47. Chromosome Rearrangement Patterns in Mammalian Evolution
      48. Chromosome Rearrangements
      49. Chromosome Structure
      50. Chromosome Structures: Visualization
      51. Chromosome X
      52. Chromosome X: General Features
      53. Chromosome Y
      54. Chromosome-specific Repeats (Low-copy Repeats)
      55. Chromosomes and Chromatin
      56. Chromosomes during Cell Division
      57. Chromosomes in Mammals: Diversity and Evolution
      58. Chromosomes: Methods for Preparation
      59. Chromosomes: Nonhistone Proteins
      60. Cis-Regulatory Mutations in Human Disease
      61. Clinical and Phenotypic Relevance of cis-Acting Regulatory Polymorphisms
      62. Clinical Molecular Cytogenetics
      63. Clustering of Highly Expressed Genes in the Human Genome
      64. Comparative Chromosome Mapping: Rodent Models
      65. Comparative Cytogenetics Technologies
      66. Comparing the Human and Fish Genomes
      67. Comparison of Rates and Patterns of Meiotic Recombination between Human and Chimpanzee
      68. Compensatory Evolution in Disease-Associated Genes
      69. CpG Islands and DNA Methylation
      70. Cytogenetic and Physical Chromosomal Maps: Integration
      71. Cytogenetic Techniques
      72. De Novo Methylation in Cancer
      73. Divergence between the Human and Chimpanzee Genomes and its Impact on Protein and Transcriptome Evolution
      74. DNA Chemical Instability
      75. DNA Demethylation
      76. DNA Looping and Transcription Regulation
      77. DNA Methylation
      78. DNA Methylation and Histone Acetylation
      79. DNA Methylation and Mutation
      80. DNA Methylation in Development
      81. DNA Methylation: Enzymology
      82. DNA Methylation: Evolution
      83. DNA Packaging in Sperm
      84. You have free access to this content
        DNA Recombination
      85. You have free access to this content
        DNA Repair
      86. You have free access to this content
        DNA Replication
      87. You have free access to this content
        DNA Replication Fidelity
      88. DNA Replication Origins
      89. DNA Structure Changes Coupled to Protein Binding
      90. DNA/RNA Flexibility
      91. Dosage Compensation Mechanisms: Evolution
      92. Enhancers
      93. Environmental Carcinogens and Mutagens
      94. Epigenetic Factors and Chromosome Organization
      95. Epigenetic Regulation in Plants
      96. Epigenetic Variation in Humans
      97. Epimutations and Cancer Susceptibility
      98. Eukaryotic Chromosomes
      99. Evolution of Common Fragile Sites
      100. Evolution of Genome Organization
      101. Evolution of Human Retrosequences: Alu
      102. Evolution of Imprinting: Imprinted Gene Function in Human Disease
      103. Evolution of X-Chromosome Inactivation
      104. Fetal Wastage: Molecular Basis
      105. Fluorescence In Situ Hybridization (FISH) Techniques
      106. Fragile Sites
      107. Fragile Sites and Human Disease
      108. Fusion Proteins and Diseases
      109. Gene Distribution in Human Chromosomes
      110. Gene Duplication and Redundancy
      111. Gene Mapping: Comparative
      112. You have free access to this content
        Gene Silencing in Development (Drosophila)
      113. You have free access to this content
        Gene Structure and Organization
      114. Genetic Conflict and Imprinting
      115. Genetic Engineering: Reporter Genes
      116. Genetic Imprinting in the Prader–Willi and Angelman Syndromes
      117. Genetic Mapping: Comparison of Direct and Indirect Approaches
      118. Genetics and Genomics of Malignant Rhabdoid Tumours
      119. Genetics of Silver–Russell Syndrome
      120. Genome Inserts
      121. Genome Organisation and Chromosome Architecture from Interphase to Metaphase
      122. Genome Size
      123. Genomic Imprinting at the Transcriptional Level
      124. Heterochromatin and Euchromatin
      125. Heterochromatin: Constitutive
      126. Hidden Markov Models
      127. Histone Acetylation and Disease
      128. Histone Acetylation: Long-range Patterns in the Genome
      129. Histones
      130. Histones: Gene Organisation and Post-translational Modification
      131. Homologous DNA Interactions in Interphase: Spatial Organization of Interphase Nucleus
      132. Homologous Genetic Recombination during Bacterial Conjugation
      133. Hotspots of Mammalian Chromosome Evolution
      134. Human Chromosome Evolution
      135. Human Chromosomes
      136. You have free access to this content
        Human Gene Therapy
      137. Human Topoisomerase I Inhibitors
      138. Immunoglobulin Genes
      139. Imprinting (Mammals)
      140. Intron Homing
      141. Intronless Genes
      142. Isochores
      143. Karyotype Analysis and Chromosome Banding
      144. Karyotype Evolution
      145. Karyotype Interpretation
      146. Kinetochore: Structure, Function and Evolution
      147. Knockout and Knock-in Animals
      148. L Isochore Map: Gene-poor Isochores
      149. Ligation: Theory and Practice
      150. Linkage and Crossing over
      151. Locus Control Regions (LCRs)
      152. Long Interspersed Nuclear Elements (LINEs)
      153. Long Noncoding RNAs and Cancer
      154. Mammalian Artificial Chromosomes (MACs)
      155. Matrix-associated Regions (MARs) and Scaffold Attachment Regions (SARs)
      156. You have free access to this content
        Mechanisms of X-inactivation
      157. Megasatellite DNA
      158. Meiotic Sex Chromosome Inactivation
      159. Methylated DNA-binding Proteins
      160. Methylation-mediated Transcriptional Silencing in Tumorigenesis
      161. Microdeletions and Microduplications: Mechanism
      162. Microsatellite Instability
      163. Mismatch Repair Genes
      164. Mitochondrial Origins of Human Nuclear Genes and DNA Sequences
      165. Mitosis and Meiosis: Molecular Control of Chromosome Separation
      166. Mitosis: Chromosome Segregation and Stability
      167. Molecular Genetics of Mental Retardation
      168. Mouse Knockouts: Modifying the Mouse Genome by using Embryonic Stem Cells
      169. Mouse N-ethyl-N-nitrosourea (ENU) Mutagenesis
      170. Negative Regulatory Elements (NREs)
      171. Non-B DNA Structure and Mutations Causing Human Genetic Disease
      172. You have free access to this content
        Nucleic Acids as Genetic Material
      173. Nucleolar Dominance
      174. Nucleosomes: Detailed Structure and Mutations
      175. Nucleosomes: Structure and Function
      176. Paramutation in Plants
      177. Plant Centromeres
      178. Plant Mutagenesis and Mutant Screening
      179. Polyploidy
      180. You have free access to this content
        Polytene Chromosomes
      181. Position Effect Variegation in Human Genetic Disease
      182. Pseudoautosomal Inheritance
      183. Relevance of Copy Number Variation to Human Genetic Disease
      184. Restriction Enzymes
      185. Retroviral Repeat Sequences
      186. Retroviruses in Human Gene Therapy
      187. Role of Chromosomal Reorganisations in the Human–Chimpanzee Speciation
      188. S-Adenosylmethionine
      189. Segmental Duplications and Genetic Disease
      190. Segmental Duplications: A Source of Diversity, Evolution and Disease
      191. Short Interspersed Elements (SINEs)
      192. Site-specific Recombination in Chromosome Function
      193. Somatic Hypermutation in Antibody Evolution
      194. Sotos Syndrome
      195. Stress-induced Premature Senescence (SIPS)
      196. Studying Genomic Aberrations by Microarray Profiling
      197. SWI/SNF Chromatin Remodelling and Human Cancer
      198. Telomere
      199. Telomere Dysfunction in Human Genetic Disease
      200. Telomeres
      201. Telomeres in Cell Function: Cancer and Ageing
      202. Telomeres: Protection and Maintenance
      203. Telomeric and Subtelomeric Repeat Sequences
      204. The Gene Content of Mammalian and Avian Sex Chromosomes
      205. Tissue-specific Locus Control: Structure and Function
      206. Transcriptional Regulation: Coordination
      207. Transgenerational Impact of Nutrition on Disease Risk
      208. Transgenic Mice Production
      209. Transgenic Plants
      210. Transgenic Xenopus Production
      211. Translocation Breakpoints in Cancer
      212. Transposons
      213. Transposons as Natural and Experimental Mutagens
      214. Transposons in Eukaryotes (Part B): Genomic Consequences of Transposition
      215. Trinucleotide Repeat Expansions: Mechanisms and Disease Associations
      216. Uniparental Disomy in Cancer – A New Tool in Molecular Cancer
      217. X and Y Chromosomes: Homologous Regions
      218. X-Chromosome Inactivation
      219. X-chromosome Inactivation
      220. X-chromosome Inactivation and Disease
      221. Xenopus as an Experimental Organism
      222. Y Chromosome
      223. Y Chromosome Evolution
      224. Y-chromosome-linked Traits
    2. Computational Molecular Biology
    3. DNA Damage and Repair
    4. DNA Structure and function
    5. Evolution of Coding and Functional Modules
    6. General Molecular Biology
    7. Genetic Code
    8. Mechanisms of Cell Death, Senescence and Metabolism
    9. Nonchromosomal DNA
    10. Noncoding RNA
    11. Posttranscriptional Modification
    12. Posttranslational Modification
    13. Protein Degradation
    14. RNA Structure and Function
    15. Techniques and Tools in Molecular Biology
    16. Transcription
    17. Transcription of DNA
    18. Transcriptional Regulation
    19. Translation of RNA
    20. Translational Regulation
  15. Neuroscience
  16. Plant Science
  17. Sample Preparation in Structural Biology
  18. Science & Society
  19. Structural Biology
  20. Techniques and Tools in Molecular Biology
  21. Techniques in Cell Biology
  22. Virology