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Copyright © 1999-2014 by John Wiley and Sons, Inc. All Rights Reserved.

Online ISBN: 9780470015902
DOI: 10.1002/047001590X
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- Biochemistry
- Biochemical and Biophysical Techniques
- Biochemistry of Cell Motility
- Bioenergetics
- Biomolecular Interactions
- Cell Signalling
- Cell Structure
- Enzymes: Structure and Action Mechanism
- General Biochemistry
- Information Flow
- Lipids: Structure, Function, Metabolism
- Molecular Transport
- Nucleic Acids: Structure, Function, Metabolism
- Other Biomolecules: Structure, Function, Metabolism
- Proteins: Structure, Function, Metabolism
- Actin and Actin Filaments
- Affinity of Antigen–Antibody Interactions
- Agglutination Techniques for Detecting Antigen–Antibody Reactions
- Amidohydrolase Superfamily
- You have free access to this contentAmino Acid Biosynthesis
- Amino Acid Degradation
- Amino Acid Side-chain Hydrophobicity
- Amino Acid Substitutions: Effects on Protein Stability
- Amyloid State of Proteins in Human Disease
- Animal Nutrient Requirements
- Anorexigenic Peptides in Health and Disease
- Antibody Classes
- Antitrypsin (AAT) Deficiency-α1
- Apolipoprotein Gene Structure and Function
- Array-based Proteomics
- ATP-binding Motifs
- Automated Protein Production Technologies
- Bacterial Ribosomes: Assembly
- BH3-Only Proteins
- Biochemistry of Toll-Like Receptors
- Biological Macromolecules: UV-visible Spectrophotometry
- Blood Clotting: General Pathway
- Blood Coagulation
- Calcium-Binding Proteins
- Capillary Electrophoresis
- Catalysis of Disulfide Bond Formation by the Quiescin Sulfhydryl Oxidases
- Cell Macromolecules
- Cell Membranes: Intracellular pH and Electrochemical Potential
- Cell Surface Glycoconjugates
- Cellulose Biosynthesis in Higher Plants and the Role of the Cytoskeleton
- Centromeres
- Chaperones, Chaperonins and Heat-Shock Proteins
- Chaperonins
- Chlorophyll: Structure and Function
- Chromatin Recognition Protein Modules: The PHD Finger
- Chromatin Remodelling and Histone Modification in Transcription Regulation
- Chromosomes: Nonhistone Proteins
- Circadian Programmes in Cyanobacteria
- Circular Dichroism: Studies of Proteins
- Clathrin-coated Vesicles and Receptor-mediated Endocytosis
- Coenzymes: Haem
- Comparative Vertebrate Muscle Physiology
- Conjugation of Proteins with Horseradish Peroxidase (HRP)
- Cornification Diseases (Skin Cell Death)
- Cornification of the Skin: A Non-apoptotic Cell Death Mechanism
- Crystallins
- Crystallisation of Proteins and Macromolecular Complexes: Past, Present and Future
- Cyclosporin
- Cystathionine β-synthase (CBS) Deficiency: Genetics
- Cystatins
- Cytochrome P450 (CYP) Gene Superfamily
- Cytoskeleton Dynamics: Actin in Cell Invasion
- Desminopathy
- Difference Gel Electrophoresis (DIGE)
- Direct Labelling of Proteins with 125I
- Disordered Proteins
- Disorders with Synuclein Pathology and Parkinsonism
- Disulfide Bonds
- DNA Helicases
- DNA Methylation
- You have free access to this contentDNA Replication
- DNA Replication: Prokaryotes and Yeast
- DNA-binding Enzymes: Structural Themes
- Dynein and Kinesin
- EF-Hand Calcium-Binding Proteins
- Electroelution of Proteins from Polyacrylamide Gels
- Electron Carriers: Proteins and Cofactors in Oxidative Phosphorylation
- Elongation Factors: Bacterial
- EM Analysis of Protein Structure
- Engineered Enzymes
- Epitope Mapping: B-cell Epitopes
- Eukaryotic Replication Protein A
- Eukaryotic Ribosomes: Assembly
- Extracellular Matrix
- Factor-Mediated Ribosome Assembly in Bacteria
- Fibrinogen and Fibrin
- Flavoenzymes: Covalent versus Noncovalent
- Friedreich Ataxia
- Fusion Proteins as Research Tools
- G Proteins
- Gain- and Loss-of-function Mutations in Trypsinogen
- Gel Electrophoresis of Proteins: High-resolution Two-dimensional
- Gene Expression: Frameshifting
- Genetic Adaptation and Selenium Uptake in Vertebrates
- Genomics, Pharmacogenetics and Proteomics: An Integration
- Genotype–Phenotype Relationships: Fatal Familial Insomnia and Creutzfeldt–Jakob Disease
- Ghrelin Appetite Hormone in Health and Disease
- Globin Genes: Polymorphic Variants and Mutations
- Glycoproteins
- Glycosylation and Disease
- Gonadotropin Hormones: Disorders
- Green Fluorescent Protein (GFP)
- GTP-binding Loop
- Haem Proteins
- Haem Structure and Function
- Haematopoietic Growth Factors
- Haeme Biosynthesis
- Haemoglobin: Cooperativity in Protein–Ligand Interactions
- Haemoglobinopathies
- Hair Loss: Genetics
- Heat Shock Proteins (HSPs): Structure, Function and Genetics
- Hibernation: Poikilotherms
- Histone Acetylation: Long-range Patterns in the Genome
- Histones: Gene Organisation and Post-translational Modification
- History of Protein Chemistry
- Hsp110 Chaperones
- Hsp70 Chaperones
- Hsp90 Chaperones
- Hydrogen Bonds in Proteins: Role and Strength
- Hydrophobic Interactions in Proteins
- Hydrophobicity Plots
- Identification of Protein–Protein Interactions
- Image Analysis Tools in Proteomics
- Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily
- Immunoglobulin Purification
- Immunoglobulin Superfamily
- Industrialization of Proteomics: Scaling UpProteomics Processes
- Inherited Disorders of Glycosylation
- Initiation Factors in Eukaryotes
- Interaction Networks of Proteins
- Interleukins
- Intracellular pH Measurement
- Intrinsically Disordered Proteins
- Intron Homing
- Introns: Group I Structure and Function
- Ion Exchange Chromatography
- Iron Cofactors: Nonhaem
- Iron Metabolism: Disorders
- Iron Overload and Chelation Therapy
- Iron–Sulfur Proteins: Structure, Function and Biogenesis
- Iron-Loading Anaemia
- Kallikrein–Kinin System
- Lamins: Organisation, Dynamics and Functions
- Laser Capture Microdissection in Proteomics
- LDL Receptor and Its Role in Inherited Disease
- Leucine Zipper
- Leucine Zippers
- Light-harvesting Complex
- Limits of Proteomics: Protein Solubilisation Issues
- LINC Complexes and Their Role in Human Disease
- Lipoprotein Metabolism: Structure and Function
- Lipoproteins: Genetic Disorders
- Luciferases and Light-emitting Accessory Proteins: Structural Biology
- Lysosomal Degradation of Proteins
- Mass Spectrometry: Peptide Sequencing
- Membrane Proteins
- You have free access to this contentMessenger RNA: Interaction with Ribosomes
- Methylated DNA-binding Proteins
- Microtubule Organisation in Dictyostelium
- Microtubule Plus-End-Tracking Proteins
- Mitochondria Protein Import: Methods
- Mitochondrial Outer Membrane Permeabilization
- Mitotic Spindle Assembly: The Role of Motor Proteins
- Mitotic Spindle Assembly: The Roles of Microtubule Nucleation and Assembly
- Molecular Dynamics
- Molecular Genetics of Chronic Pancreatitis
- Molecular Genetics of the α-Thalassaemias
- Molecular Genetics of von Willebrand Disease
- Molecular Machines and Human Disorders
- Molten Globule
- Motor Proteins
- mRNA Export
- mRNA Splicing: Regulated and Differential
- Multidomain Proteins
- Multidrug Resistance in Cancer: Genetics of ABC Transporters
- Muscle Contraction
- Muscle Contraction Mechanisms: Use of Synchrotron X-ray Diffraction
- Muscle Contraction: Regulation
- Myosin Superfamily
- NAD(P)+ Binding to Dehydrogenases
- Nitrogenase Complex
- NMR Spectroscopy for Monitoring Functional Dynamics in Solution
- Non-Classical MHC Class I Molecules (MHC-Ib)
- Nuclear Magnetic Resonance (NMR) of Proteins: Solid State
- Nuclear Magnetic Resonance (NMR) Spectroscopy of Proteins
- Nucleolar Proteomics
- Nucleoplasmin: A Versatile Histone Chaperone
- Nucleosomes: Detailed Structure and Mutations
- Nucleosomes: Structure and Function
- Ornithine Transcarbamylase Deficiency: Genetics
- Ovalbumin Serpins
- Oxidative Protein Folding
- Oxygen Production
- Peptidases
- Peptide Bonds, Disulfide Bonds and Properties of Small Peptides
- Peptide Mapping
- Peptide Sequencing by Edman Degradation
- Peptidyl Prolyl cis/trans Isomerases
- Peptidyl Transfer on the Ribosome
- Permeabilised Mammalian Cell Systems for Protein Synthesis
- Phosphoproteomics
- Photosystem I
- Photosystem II
- Plakin Proteins, Hemidesmosomes and Human Disease
- Plant Actin Biology
- Plant Storage Products (Carbohydrates, Oils and Proteins)
- Plant Virus Movement
- Porphyrias: Genetics
- Posttranscriptional Processing
- Prefoldins
- Preparation Artefacts in Proteomics: Technological Issues
- Primary Protein and Nucleic Acid Three-dimensional Structure Databases
- Primer on Protein–Protein Interaction Maps
- Proline Residues in Proteins
- Protease Complexes
- Protein Association with Membrane Rafts
- Protein Characterization: Analytical Approaches and Applications to Proteomics
- Protein Degradation and Turnover
- Protein Denaturation and the Denatured State
- Protein Design
- Protein Disorder and Human Genetic Disease
- Protein Disulfide Isomerases
- Protein Export from Endoplasmic Reticulum to the Cytosol: In Vitro Methods
- Protein Family Databases
- Protein Folding and Chaperones
- Protein Folding in Vivo
- Protein Folding: Overview of Pathways
- Protein Glycosylation, an Overview
- Protein Homology Modelling
- Protein Identification: Overlay Procedures
- Protein Import into Peroxisomes: The Principles and Methods of Studying
- Protein Interaction and Genetic Disease
- Protein Isoforms and Isozymes
- Protein Motifs for DNA Binding
- Protein Motifs: the Helix-Loop-Helix Motif
- Protein Motifs: the Helix-Turn-Helix Motif
- Protein Motifs: Zinc Fingers
- Protein Phosphatases
- Protein Phosphorylation and Long-term Synaptic Plasticity
- Protein Primary Structure
- Protein Quantitation: Bradford Method
- Protein Quantitation: Lowry Protocol
- Protein Quaternary Structure: Subunit–Subunit Interactions
- Protein Quaternary Structure: Symmetry Patterns
- Protein Secondary Structures: Prediction
- Protein Secretory Pathways
- Protein Sequence Databases
- Protein Stability
- Protein Structural Flexibility: Molecular Motions
- Protein Structure
- Protein Structure Design and Engineering
- Protein Structure Prediction and Databases
- Protein Structure: Unusual Covalent Bonds
- Protein Superfamilies
- Protein Synthesis: Measuring Errors
- Protein Targeting
- Protein Tertiary Structures: Prediction from Amino Acid Sequences
- Protein Translocation across Membranes
- Protein Transport
- Protein Unfolding and Denaturants
- Protein–DNA Interactions
- Protein–Protein Interactions: The Structural Foundation of Life Complexity
- Protein-Derived Cofactors
- Protein–DNA Interactions: Techniques Used
- Protein–Ligand Interactions: Computational Docking
- Protein–Ligand Interactions: Energetic Contributions and Shape Complementarity
- Protein–Ligand Interactions: General Description
- Protein–Ligand Interactions: Induced Fit
- Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants
- Protein–protein Interactions: Identification
- Protein: Cotranslational and Posttranslational Modification in Organelles
- Proteins: Affinity Tags
- Proteins: Fundamental Chemical Properties
- Proteins: Mutational Effects in
- Proteins: Postsynthetic Modification – Function and Physical Analysis
- Proteoglycans
- Purifying and Analysing Cytosolic Protein Complexes
- Quality Control of Protein Folding in the Cytosol
- Quantitative Proteomics (ICAT™)
- Rad51 and Eukaryotic Recombination Proteins
- RecA Protein
- RecFOR Protein
- Regulation by Covalent Modification
- Regulatory Cascade
- Regulatory Systems: Two-component
- Repression Mechanism
- Rhodopsin
- Ribosomal Proteins in Eukaryotes
- Ribosomal Proteins: Role in Ribosomal Functions
- Ribosomal Proteins: Structure and Evolution
- RNA-binding Proteins: Regulation of mRNA Splicing, Export and Decay
- Role of Plakins in Human Genetic Disease
- The Role of the RanGTPase in Mitotic Spindle Assembly
- Selenocysteine
- Serine Proteases
- Shotgun Proteomics
- Sickle Cell Disease as a Multifactorial Condition
- Single-stranded DNA-binding Proteins
- Small-Angle Scattering of Neutrons and X-Rays
- Sodium, Calcium and Potassium Channels
- Solid-phase Peptide Synthesis: Fmoc
- Spliceosomal Machinery
- SR Proteins
- Starvation: Metabolic Changes
- Structural Basis of Disulfide Bond Formation in the Bacterial Periplasm and Mammalian ER
- Structural Databases of Biological Macromolecules
- Structural Predictions and Modeling
- Structural Proteins: Genes for Collagen
- Structural Proteomics: Large-Scale Studies
- SUMOylation
- Synaptic Vesicle Proteins
- Tandem Affinity Purification (TAP) Tags
- Telomeres and Telomerase in Ageing and Cancer
- Thalassaemias
- Thalassemias
- The MERTK Signalling Pathway in Cancer
- The Plasminogen Activation System
- Thermosome: A Group II Chaperonin of Archaea
- Titin Gene (TTN)
- Toxin Action: Molecular Mechanisms
- Transcription Activation in Eukaryotic Cells
- Transcription and Translation In Vitro
- Transcriptomics and Proteomics: Integration?
- Transfer RNA Synthetase Editing of Errors in Amino Acid Selection
- Translation Control by Proteins
- Translation Control by RNA
- Transmembrane Domains
- Tuberous Sclerosis Complex and the Mammalian Target of Rapamycin Pathways
- Tubulin and Microtubules
- Tubulin Folding and Degradation
- Two-dimensional Electron Crystallography
- Two-dimensional Gel Electrophoresis
- Two-Hybrid and Related Systems
- Two-Hybrid Systems to Measure Protein–Protein Interactions
- Ubiquitin Pathway
- Venous Thrombosis: Genetics
- Virus Structure
- Vitamin K-dependent Carboxylase
- Water Channels
- Zinc-finger Genes
- Bioethics & Philosophy
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- Developmental Biology
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- Evolution & Diversity of Life
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