eLS

eLS

Online ISBN: 9780470015902

DOI: 10.1002/047001590X

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  1. Biochemistry
    1. Biochemical and Biophysical Techniques
    2. Biochemistry of Cell Motility
    3. Bioenergetics
    4. Biomolecular Interactions
    5. Cell Signalling
    6. Cell Structure
    7. Enzymes: Structure and Action Mechanism
    8. General Biochemistry
    9. Information Flow
    10. Lipids: Structure, Function, Metabolism
    11. Molecular Transport
    12. Nucleic Acids: Structure, Function, Metabolism
    13. Other Biomolecules: Structure, Function, Metabolism
    14. Proteins: Structure, Function, Metabolism
      1. Actin and Actin Filaments
      2. Affinity of Antigen–Antibody Interactions
      3. Agglutination Techniques for Detecting Antigen–Antibody Reactions
      4. Amidohydrolase Superfamily
      5. You have free access to this content
        Amino Acid Biosynthesis
      6. Amino Acid Degradation
      7. Amino Acid Side-chain Hydrophobicity
      8. Amino Acid Substitutions: Effects on Protein Stability
      9. Amyloid State of Proteins in Human Disease
      10. Animal Nutrient Requirements
      11. Anorexigenic Peptides in Health and Disease
      12. Antibody Classes
      13. Antitrypsin (AAT) Deficiency-α1
      14. Apolipoprotein Gene Structure and Function
      15. Array-based Proteomics
      16. ATP-binding Motifs
      17. Automated Protein Production Technologies
      18. Bacterial Ribosomes: Assembly
      19. BH3-Only Proteins
      20. Biochemistry of Toll-Like Receptors
      21. Biological Macromolecules: UV-visible Spectrophotometry
      22. Blood Clotting: General Pathway
      23. Blood Coagulation
      24. Calcium-Binding Proteins
      25. Capillary Electrophoresis
      26. Catalysis of Disulfide Bond Formation by the Quiescin Sulfhydryl Oxidases
      27. Cell Macromolecules
      28. Cell Membranes: Intracellular pH and Electrochemical Potential
      29. Cell Surface Glycoconjugates
      30. Cellulose Biosynthesis in Higher Plants and the Role of the Cytoskeleton
      31. Centromeres
      32. Chaperones, Chaperonins and Heat-Shock Proteins
      33. Chaperonins
      34. Chlorophyll: Structure and Function
      35. Chromatin Recognition Protein Modules: The PHD Finger
      36. Chromatin Remodelling and Histone Modification in Transcription Regulation
      37. Chromosomes: Nonhistone Proteins
      38. Circadian Programmes in Cyanobacteria
      39. Circular Dichroism: Studies of Proteins
      40. Clathrin-coated Vesicles and Receptor-mediated Endocytosis
      41. Coenzymes: Haem
      42. Comparative Vertebrate Muscle Physiology
      43. Conjugation of Proteins with Horseradish Peroxidase (HRP)
      44. Cornification Diseases (Skin Cell Death)
      45. Cornification of the Skin: A Non-apoptotic Cell Death Mechanism
      46. Crystallins
      47. Crystallisation of Proteins and Macromolecular Complexes: Past, Present and Future
      48. Cyclosporin
      49. Cystathionine β-synthase (CBS) Deficiency: Genetics
      50. Cystatins
      51. Cytochrome P450 (CYP) Gene Superfamily
      52. Cytoskeleton Dynamics: Actin in Cell Invasion
      53. Desminopathy
      54. Difference Gel Electrophoresis (DIGE)
      55. Direct Labelling of Proteins with 125I
      56. Disordered Proteins
      57. Disorders with Synuclein Pathology and Parkinsonism
      58. Disulfide Bonds
      59. DNA Helicases
      60. DNA Methylation
      61. You have free access to this content
        DNA Replication
      62. DNA Replication: Prokaryotes and Yeast
      63. DNA-binding Enzymes: Structural Themes
      64. Dynein and Kinesin
      65. EF-Hand Calcium-Binding Proteins
      66. Electroelution of Proteins from Polyacrylamide Gels
      67. Electron Carriers: Proteins and Cofactors in Oxidative Phosphorylation
      68. Elongation Factors: Bacterial
      69. EM Analysis of Protein Structure
      70. Engineered Enzymes
      71. Epitope Mapping: B-cell Epitopes
      72. Eukaryotic Replication Protein A
      73. Eukaryotic Ribosomes: Assembly
      74. Extracellular Matrix
      75. Factor-Mediated Ribosome Assembly in Bacteria
      76. Fibrinogen and Fibrin
      77. Flavoenzymes: Covalent versus Noncovalent
      78. Friedreich Ataxia
      79. Fusion Proteins as Research Tools
      80. G Proteins
      81. Gain- and Loss-of-function Mutations in Trypsinogen
      82. Gel Electrophoresis of Proteins: High-resolution Two-dimensional
      83. Gene Expression: Frameshifting
      84. Genetic Adaptation and Selenium Uptake in Vertebrates
      85. Genomics, Pharmacogenetics and Proteomics: An Integration
      86. Genotype–Phenotype Relationships: Fatal Familial Insomnia and Creutzfeldt–Jakob Disease
      87. Ghrelin Appetite Hormone in Health and Disease
      88. Globin Genes: Polymorphic Variants and Mutations
      89. Glycoproteins
      90. Glycosylation and Disease
      91. Gonadotropin Hormones: Disorders
      92. Green Fluorescent Protein (GFP)
      93. GTP-binding Loop
      94. Haem Proteins
      95. Haem Structure and Function
      96. Haematopoietic Growth Factors
      97. Haeme Biosynthesis
      98. Haemoglobin: Cooperativity in Protein–Ligand Interactions
      99. Haemoglobinopathies
      100. Hair Loss: Genetics
      101. Heat Shock Proteins (HSPs): Structure, Function and Genetics
      102. Hibernation: Poikilotherms
      103. Histone Acetylation: Long-range Patterns in the Genome
      104. Histones: Gene Organisation and Post-translational Modification
      105. History of Protein Chemistry
      106. Hsp110 Chaperones
      107. Hsp70 Chaperones
      108. Hsp90 Chaperones
      109. Hydrogen Bonds in Proteins: Role and Strength
      110. Hydrophobic Interactions in Proteins
      111. Hydrophobicity Plots
      112. Identification of Protein–Protein Interactions
      113. Image Analysis Tools in Proteomics
      114. Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily
      115. Immunoglobulin Purification
      116. Immunoglobulin Superfamily
      117. Industrialization of Proteomics: Scaling UpProteomics Processes
      118. Inherited Disorders of Glycosylation
      119. Initiation Factors in Eukaryotes
      120. Interaction Networks of Proteins
      121. Interleukins
      122. Intracellular pH Measurement
      123. Intrinsically Disordered Proteins
      124. Intron Homing
      125. Introns: Group I Structure and Function
      126. Ion Exchange Chromatography
      127. Iron Cofactors: Nonhaem
      128. Iron Metabolism: Disorders
      129. Iron Overload and Chelation Therapy
      130. Iron–Sulfur Proteins: Structure, Function and Biogenesis
      131. Iron-Loading Anaemia
      132. Kallikrein–Kinin System
      133. Lamins: Organisation, Dynamics and Functions
      134. Laser Capture Microdissection in Proteomics
      135. LDL Receptor and Its Role in Inherited Disease
      136. Lectins
      137. Leucine Zipper
      138. Leucine Zippers
      139. Light-harvesting Complex
      140. Limits of Proteomics: Protein Solubilisation Issues
      141. LINC Complexes and Their Role in Human Disease
      142. Lipoprotein Metabolism: Structure and Function
      143. Lipoproteins: Genetic Disorders
      144. Luciferases and Light-emitting Accessory Proteins: Structural Biology
      145. Lysosomal Degradation of Proteins
      146. Lysozyme
      147. Mass Spectrometry: Peptide Sequencing
      148. Membrane Proteins
      149. You have free access to this content
        Messenger RNA: Interaction with Ribosomes
      150. Methylated DNA-binding Proteins
      151. Microtubule Organisation in Dictyostelium
      152. Microtubule Plus-End-Tracking Proteins
      153. Mitochondria Protein Import: Methods
      154. Mitochondrial Outer Membrane Permeabilization
      155. Mitotic Spindle Assembly: The Role of Motor Proteins
      156. Mitotic Spindle Assembly: The Roles of Microtubule Nucleation and Assembly
      157. Molecular Dynamics
      158. Molecular Genetics of Chronic Pancreatitis
      159. Molecular Genetics of the α-Thalassaemias
      160. Molecular Genetics of von Willebrand Disease
      161. Molecular Machines and Human Disorders
      162. Molten Globule
      163. Motor Proteins
      164. mRNA Export
      165. mRNA Splicing: Regulated and Differential
      166. Multidomain Proteins
      167. Multidrug Resistance in Cancer: Genetics of ABC Transporters
      168. Muscle Contraction
      169. Muscle Contraction Mechanisms: Use of Synchrotron X-ray Diffraction
      170. Muscle Contraction: Regulation
      171. Myoglobin
      172. Myosin Superfamily
      173. NAD(P)+ Binding to Dehydrogenases
      174. Nitrogenase Complex
      175. NMR Spectroscopy for Monitoring Functional Dynamics in Solution
      176. Non-Classical MHC Class I Molecules (MHC-Ib)
      177. Nuclear Magnetic Resonance (NMR) of Proteins: Solid State
      178. Nuclear Magnetic Resonance (NMR) Spectroscopy of Proteins
      179. Nucleolar Proteomics
      180. Nucleoplasmin: A Versatile Histone Chaperone
      181. Nucleosomes: Detailed Structure and Mutations
      182. Nucleosomes: Structure and Function
      183. OD Unit
      184. Ornithine Transcarbamylase Deficiency: Genetics
      185. Ovalbumin Serpins
      186. Oxidative Protein Folding
      187. Oxygen Production
      188. Peptidases
      189. Peptide Bonds, Disulfide Bonds and Properties of Small Peptides
      190. Peptide Mapping
      191. Peptide Sequencing by Edman Degradation
      192. Peptidyl Prolyl cis/trans Isomerases
      193. Peptidyl Transfer on the Ribosome
      194. Permeabilised Mammalian Cell Systems for Protein Synthesis
      195. Phosphoproteomics
      196. Photosystem I
      197. Photosystem II
      198. Plakin Proteins, Hemidesmosomes and Human Disease
      199. Plant Actin Biology
      200. Plant Storage Products (Carbohydrates, Oils and Proteins)
      201. Plant Virus Movement
      202. Porphyrias: Genetics
      203. Posttranscriptional Processing
      204. Prefoldins
      205. Preparation Artefacts in Proteomics: Technological Issues
      206. Primary Protein and Nucleic Acid Three-dimensional Structure Databases
      207. Primer on Protein–Protein Interaction Maps
      208. Proline Residues in Proteins
      209. Protease Complexes
      210. Protein Association with Membrane Rafts
      211. Protein Characterization: Analytical Approaches and Applications to Proteomics
      212. Protein Degradation and Turnover
      213. Protein Denaturation and the Denatured State
      214. Protein Design
      215. Protein Disorder and Human Genetic Disease
      216. Protein Disulfide Isomerases
      217. Protein Export from Endoplasmic Reticulum to the Cytosol: In Vitro Methods
      218. Protein Family Databases
      219. Protein Folding and Chaperones
      220. Protein Folding in Vivo
      221. Protein Folding: Overview of Pathways
      222. Protein Glycosylation, an Overview
      223. Protein Homology Modelling
      224. Protein Identification: Overlay Procedures
      225. Protein Import into Peroxisomes: The Principles and Methods of Studying
      226. Protein Interaction and Genetic Disease
      227. Protein Isoforms and Isozymes
      228. Protein Motifs for DNA Binding
      229. Protein Motifs: the Helix-Loop-Helix Motif
      230. Protein Motifs: the Helix-Turn-Helix Motif
      231. Protein Motifs: Zinc Fingers
      232. Protein Phosphatases
      233. Protein Phosphorylation and Long-term Synaptic Plasticity
      234. Protein Primary Structure
      235. Protein Quantitation: Bradford Method
      236. Protein Quantitation: Lowry Protocol
      237. Protein Quaternary Structure: Subunit–Subunit Interactions
      238. Protein Quaternary Structure: Symmetry Patterns
      239. Protein Secondary Structures: Prediction
      240. Protein Secretory Pathways
      241. Protein Sequence Databases
      242. Protein Stability
      243. Protein Structural Flexibility: Molecular Motions
      244. Protein Structure
      245. Protein Structure Design and Engineering
      246. Protein Structure Prediction and Databases
      247. Protein Structure: Unusual Covalent Bonds
      248. Protein Superfamilies
      249. Protein Synthesis: Measuring Errors
      250. Protein Targeting
      251. Protein Tertiary Structures: Prediction from Amino Acid Sequences
      252. Protein Translocation across Membranes
      253. Protein Transport
      254. Protein Unfolding and Denaturants
      255. Protein–DNA Interactions
      256. Protein–Protein Interactions: The Structural Foundation of Life Complexity
      257. Protein-Derived Cofactors
      258. Protein–DNA Interactions: Techniques Used
      259. Protein–Ligand Interactions: Computational Docking
      260. Protein–Ligand Interactions: Energetic Contributions and Shape Complementarity
      261. Protein–Ligand Interactions: General Description
      262. Protein–Ligand Interactions: Induced Fit
      263. Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants
      264. Protein–protein Interactions: Identification
      265. Protein: Cotranslational and Posttranslational Modification in Organelles
      266. Proteins: Affinity Tags
      267. Proteins: Fundamental Chemical Properties
      268. Proteins: Mutational Effects in
      269. Proteins: Postsynthetic Modification – Function and Physical Analysis
      270. Proteoglycans
      271. Purifying and Analysing Cytosolic Protein Complexes
      272. Quality Control of Protein Folding in the Cytosol
      273. Quantitative Proteomics (ICAT™)
      274. Rad51 and Eukaryotic Recombination Proteins
      275. RecA Protein
      276. RecFOR Protein
      277. Regulation by Covalent Modification
      278. Regulatory Cascade
      279. Regulatory Systems: Two-component
      280. Repression Mechanism
      281. Rhodopsin
      282. Ribosomal Proteins in Eukaryotes
      283. Ribosomal Proteins: Role in Ribosomal Functions
      284. Ribosomal Proteins: Structure and Evolution
      285. RNA-binding Proteins: Regulation of mRNA Splicing, Export and Decay
      286. Role of Plakins in Human Genetic Disease
      287. The Role of the RanGTPase in Mitotic Spindle Assembly
      288. Rubisco
      289. Selenocysteine
      290. Serine Proteases
      291. Shotgun Proteomics
      292. Sickle Cell Disease as a Multifactorial Condition
      293. Single-stranded DNA-binding Proteins
      294. Small-Angle Scattering of Neutrons and X-Rays
      295. Sodium, Calcium and Potassium Channels
      296. Solid-phase Peptide Synthesis: Fmoc
      297. Spliceosomal Machinery
      298. SR Proteins
      299. Starvation: Metabolic Changes
      300. Structural Basis of Disulfide Bond Formation in the Bacterial Periplasm and Mammalian ER
      301. Structural Databases of Biological Macromolecules
      302. Structural Predictions and Modeling
      303. Structural Proteins: Genes for Collagen
      304. Structural Proteomics: Large-Scale Studies
      305. SUMOylation
      306. Synaptic Vesicle Proteins
      307. Tandem Affinity Purification (TAP) Tags
      308. Telomeres and Telomerase in Ageing and Cancer
      309. Thalassaemias
      310. Thalassemias
      311. The MERTK Signalling Pathway in Cancer
      312. The Plasminogen Activation System
      313. Thermosome: A Group II Chaperonin of Archaea
      314. Thrombin
      315. Titin Gene (TTN)
      316. Toxin Action: Molecular Mechanisms
      317. Transcription Activation in Eukaryotic Cells
      318. Transcription and Translation In Vitro
      319. Transcriptomics and Proteomics: Integration?
      320. Transfer RNA Synthetase Editing of Errors in Amino Acid Selection
      321. Translation Control by Proteins
      322. Translation Control by RNA
      323. Transmembrane Domains
      324. Tuberous Sclerosis Complex and the Mammalian Target of Rapamycin Pathways
      325. Tubulin and Microtubules
      326. Tubulin Folding and Degradation
      327. Two-dimensional Electron Crystallography
      328. Two-dimensional Gel Electrophoresis
      329. Two-Hybrid and Related Systems
      330. Two-Hybrid Systems to Measure Protein–Protein Interactions
      331. Ubiquitin Pathway
      332. Venous Thrombosis: Genetics
      333. Virus Structure
      334. Vitamin K-dependent Carboxylase
      335. Water Channels
      336. Zinc-finger Genes
  2. Bioethics & Philosophy
  3. Cell Biology
  4. Developmental Biology
  5. Ecology
  6. Evolution & Diversity of Life
  7. Genetics & Disease
  8. Immunology
  9. Microbiology
  10. Molecular Biology
  11. Neuroscience
  12. Plant Science
  13. Science & Society
  14. Structural Biology
  15. Virology

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