eLS

Copyright © 1999-2014 by John Wiley and Sons, Inc. All Rights Reserved.

eLS

Online ISBN: 9780470015902

DOI: 10.1002/047001590X

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  1. Biochemistry
  2. Bioethics & Philosophy
  3. Cell Biology
  4. Developmental Biology
  5. Ecology
  6. Evolution & Diversity of Life
  7. Genetics & Disease
  8. Immunology
  9. Microbiology
  10. Molecular Biology
  11. Neuroscience
  12. Plant Science
  13. Science & Society
  14. Structural Biology
    1. Bioinformatics
    2. Cell Motility and Transport
    3. Electron Microscopy
    4. General Structural Biology
    5. Lipids and Membrane Structure
    6. Mass Spectrometry
    7. Membrane Proteins
    8. Nuclear Magnetic Resonance
    9. Nucleic Acid Structure
    10. Optical Microscopy
    11. Protein Folding, Evolution and Degradation
    12. Protein Structure
      1. Actin and Actin Filaments
      2. Amidohydrolase Superfamily
      3. Amino Acid Side-chain Hydrophobicity
      4. Amino Acid Substitutions: Effects on Protein Stability
      5. γ-Aminobutyric Acid (GABA) Receptors
      6. AMPA Receptors
      7. Amyloid State of Proteins in Human Disease
      8. Amyloidosis
      9. Antibody Classes
      10. Antigen–Antibody Binding
      11. Antitrypsin (AAT) Deficiency-α1
      12. Archaeal Ribosomes
      13. ATP-binding Motifs
      14. Automated Protein Production Technologies
      15. Baculovirus Expression Strategies for Protein Complex Production
      16. Biological Macromolecules: UV-visible Spectrophotometry
      17. Biotin
      18. BLAST Algorithm
      19. Blood Group Genetics
      20. Calcium-Binding Proteins
      21. Caspases and Cell Death
      22. Caspases, Substrates and Sequential Activation
      23. Catalysis of Disulfide Bond Formation by the Quiescin Sulfhydryl Oxidases
      24. Cell Locomotion
      25. Chaperonins
      26. Chlorophyll-Binding Proteins
      27. Chlorophyll: Structure and Function
      28. Chromatin Recognition Protein Modules: The PHD Finger
      29. Chromatin Remodelling and Histone Modification in Transcription Regulation
      30. Chromatin Structure and Domains
      31. Chromosomal Bands and Sequence Features
      32. Chromosomes: Nonhistone Proteins
      33. Cilia and Flagella
      34. Circular Dichroism: Studies of Proteins
      35. Cobalamin Coenzymes and Vitamin B12
      36. Coenzymes: Haem
      37. Complement: Terminal Pathways
      38. Cryogenic Detectors: Detection of Single Molecules
      39. Crystallins
      40. Crystallisation of Proteins and Macromolecular Complexes: Past, Present and Future
      41. Crystallization of Protein–DNA Complexes
      42. Cystatins
      43. Cytoskeleton
      44. Cytoskeleton Dynamics: Actin in Cell Invasion
      45. Deafness
      46. Death Receptors at the Molecular Level: Therapeutic Implications
      47. Difference Gel Electrophoresis (DIGE)
      48. Disordered Proteins
      49. Disulfide Bonds
      50. DNA Helicases
      51. DNA Methylation
      52. You have free access to this content
        DNA Replication
      53. DNA-binding Enzymes: Structural Themes
      54. Dynamic Programming
      55. Dynein and Kinesin
      56. EF-Hand Calcium-Binding Proteins
      57. Electron Cryomicroscopy and Three-dimensional Computer Reconstruction of Biological Molecules
      58. Electron Paramagnetic Resonance (EPR) and Spin-labelling
      59. EM Analysis of Protein Structure
      60. Engineered Enzymes
      61. Enzyme Activity: Allosteric Regulation
      62. Enzyme Activity: Control
      63. Enzyme Specificity and Selectivity
      64. Enzymes: Phosphopantetheine-dependent
      65. Enzymes: The Active Site
      66. Epitope Mapping: B-cell Epitopes
      67. Erythrocyte Membrane Disorders
      68. Eukaryotic Replication Fork
      69. Eukaryotic Replication Protein A
      70. Evolution of Protein Domains
      71. Exosome Complex
      72. Expression Tags for Protein Production
      73. Fc Receptors
      74. Fibrinogen and Fibrin
      75. Flavoenzymes: Covalent versus Noncovalent
      76. Forkhead Domains
      77. From Reactive Oxygen and Nitrogen Species to Therapy
      78. Fusion Proteins as Research Tools
      79. G Protein-Coupled Receptors
      80. G Proteins
      81. Gel-Staining Techniques – Dyeing to Know It All
      82. Genome, Proteome and the Quest for a Full Structure–Function Description of an Organism
      83. Global Alignment
      84. Globin Genes: Polymorphic Variants and Mutations
      85. Glycoproteins
      86. Glycosidases: Functions, Families and Folds
      87. Glycosylation and Disease
      88. Green Fluorescent Protein (GFP)
      89. GTP-binding Loop
      90. Haem Proteins
      91. Haem Structure and Function
      92. Haemoglobin: Cooperativity in Protein–Ligand Interactions
      93. Hidden Markov Models
      94. Histones: Gene Organisation and Post-translational Modification
      95. History of Protein Chemistry
      96. Hsp110 Chaperones
      97. Hsp90 Chaperones
      98. Hydrogen Bonds in Proteins: Role and Strength
      99. Hydrophobicity Plots
      100. Identification of Protein–Protein Interactions
      101. Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily
      102. Immunoglobulin Superfamily
      103. Industrialization of Proteomics: Scaling UpProteomics Processes
      104. Inhibitor of Apoptosis (IAP) and BIR-containing Proteins
      105. Integrase Class Site-specific Recombinases
      106. Integrins
      107. Interaction Networks of Proteins
      108. Intrinsically Disordered Proteins
      109. Iron–Sulfur Proteins: Structure, Function and Biogenesis
      110. Laser Capture Microdissection in Proteomics
      111. Lectins
      112. Leucine Zipper
      113. Leucine Zippers
      114. Light-harvesting Complex
      115. Limits of Proteomics: Protein Solubilisation Issues
      116. Lipoprotein Metabolism: Structure and Function
      117. Luciferases and Light-emitting Accessory Proteins: Structural Biology
      118. Macromolecular Interactions: Light Scattering
      119. Macromolecular Structure Determination by X-ray Crystallography
      120. Major Histocompatibility Complex (MHC) Genes
      121. Major Histocompatibility Complex: Interaction with Peptides
      122. Mass Spectrometry in Protein Characterization
      123. Mass Spectrometry Instrumentation in Proteomics
      124. Mass Spectrometry: Analysis of Two-Dimensional Protein Gels
      125. Mass Spectrometry: Peptide Sequencing
      126. Membrane Insertion of Tail-anchored Proteins
      127. You have free access to this content
        Messenger RNA: Interaction with Ribosomes
      128. Metalloenzymes and Electrophilic Catalysis
      129. Microtubule Plus-End-Tracking Proteins
      130. Molecular Dynamics
      131. Molecular Entry Point: Strategies in Proteomics
      132. Molecular Genetics of the α-Thalassaemias
      133. Molecular Genetics of the Fibrillinopathies
      134. Molecular Machines and Human Disorders
      135. Molten Globule
      136. Motor Proteins
      137. Multidomain Proteins
      138. Multiple Alignment
      139. Myoglobin
      140. Myosin Superfamily
      141. NAD(P)+ Binding to Dehydrogenases
      142. Nitrogenase Complex
      143. NMR Spectroscopy for Monitoring Functional Dynamics in Solution
      144. Non-Classical MHC Class I Molecules (MHC-Ib)
      145. Nuclear Magnetic Resonance (NMR) of Proteins: Solid State
      146. Nuclear Magnetic Resonance (NMR) Spectroscopy of Proteins
      147. Nucleolar Proteomics
      148. Nucleolus: Structure and Function
      149. Nucleosomes: Detailed Structure and Mutations
      150. Nucleosomes: Structure and Function
      151. Olfactory Receptors
      152. Pattern Searches in Protein Sequences
      153. Peptidases
      154. Peptide Bonds, Disulfide Bonds and Properties of Small Peptides
      155. Peptide Mapping
      156. Peptide Sequencing by Edman Degradation
      157. Peptides: Biological Activities of Small Peptides
      158. Peptidyl Prolyl cis/trans Isomerases
      159. Phosphoproteomics
      160. Photosystem I
      161. Plant Storage Products (Carbohydrates, Oils and Proteins)
      162. Posttranslational Modification and Human Disorders
      163. Posttranslational Modifications in Plant Disease Resistance
      164. Posttranslational Processing: Peptide Hormones and Neuropeptide Transmitters
      165. Potassium Channels
      166. Preparation Artefacts in Proteomics: Technological Issues
      167. Primary Protein and Nucleic Acid Three-dimensional Structure Databases
      168. Prions
      169. Prions
      170. Profile Searching
      171. Proline Residues in Proteins
      172. Protease Complexes
      173. Protein Coding
      174. Protein Databases: Operations, Possibilities and Challenges
      175. Protein Design
      176. Protein Disorder and Human Genetic Disease
      177. Protein Disulfide Isomerases
      178. Protein Domain Fusion
      179. Protein Families: Evolution
      180. Protein Folding: Overview of Pathways
      181. Protein Homology Modelling
      182. Protein Interaction and Genetic Disease
      183. Protein Isoforms and Isozymes
      184. Protein Motifs for DNA Binding
      185. Protein Motifs: the Helix-Loop-Helix Motif
      186. Protein Motifs: the Helix-Turn-Helix Motif
      187. Protein Motifs: Zinc Fingers
      188. Protein Phosphatases
      189. Protein Primary Structure
      190. Protein Quaternary Structure: Subunit–Subunit Interactions
      191. Protein Quaternary Structure: Symmetry Patterns
      192. Protein Secondary Structures: Prediction
      193. Protein Sequence Databases
      194. Protein Stability
      195. Protein Structural Flexibility: Molecular Motions
      196. Protein Structure
      197. Protein Structure and Interactions from Nuclear Magnetic Resonance Spectroscopy
      198. Protein Structure Classification
      199. Protein Structure Design and Engineering
      200. Protein Structure Prediction
      201. Protein Structure Prediction and Databases
      202. Protein Structure: Unusual Covalent Bonds
      203. Protein Superfamilies
      204. Protein Synthesis: Measuring Errors
      205. Protein Tertiary Structures: Prediction from Amino Acid Sequences
      206. Protein–DNA Complexes: Nonspecific
      207. Protein–DNA Complexes: Specific
      208. Protein–DNA Interactions: Polyelectrolyte Effects
      209. Protein–DNA Interactions: Structure and Energetics
      210. Protein–DNA Interactions: Techniques Used
      211. Protein–Ligand Interactions: Computational Docking
      212. Protein–Ligand Interactions: Energetic Contributions and Shape Complementarity
      213. Protein–Ligand Interactions: General Description
      214. Protein–Ligand Interactions: Induced Fit
      215. Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants
      216. Protein–protein Interactions: Identification
      217. Protein–RNA Interactions
      218. Proteins: Affinity Tags
      219. Proteins: Fundamental Chemical Properties
      220. Proteins: Mutational Effects in
      221. Proteins: Postsynthetic Modification – Function and Physical Analysis
      222. Proteoglycans
      223. Proteomics: A Molecular Scanner in Medicine
      224. Purifying and Analysing Cytosolic Protein Complexes
      225. Pyruvate Dehydrogenase Complex
      226. Quantitative Proteomics (ICAT™)
      227. Rad51 and Eukaryotic Recombination Proteins
      228. Radical Enzymes
      229. Radical S-Adenosylmethionine (SAM) Superfamily
      230. RecA Protein
      231. RecFOR Protein
      232. Regulation by Covalent Modification
      233. Resonance Raman Spectroscopy
      234. Rhodopsin
      235. Ribosomal Proteins in Eukaryotes
      236. Ribosomal Proteins: Structure and Evolution
      237. Ribosomal RNA
      238. Ribosomes and Ribosomal Proteins: More Than Just ‘Housekeeping’
      239. RNA Polymerase II Holoenzyme and Transcription Factors
      240. RNA Polymerases: Subunits and Functional Domains
      241. RNA Synthesis
      242. Selenocysteine
      243. Sequence Alignment
      244. Sequence Similarity
      245. Serine Proteases
      246. Signal Peptides
      247. Single-stranded DNA-binding Proteins
      248. Small-Angle Scattering of Neutrons and X-Rays
      249. Smith–Waterman Algorithm
      250. Structural Basis of Disulfide Bond Formation in the Bacterial Periplasm and Mammalian ER
      251. Structural Databases of Biological Macromolecules
      252. Structural Genomics
      253. Structural Predictions and Modeling
      254. Structural Proteomics: Large-Scale Studies
      255. Structure and Function of IAP and Bcl-2 Proteins
      256. Structure–Function Relationships in the Aromatic Amino Acid Hydroxylases Enzyme Family: Evolutionary Insights
      257. Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD)
      258. SUMOylation
      259. Synaptic Vesicle Proteins
      260. Tandem Affinity Purification (TAP) Tags
      261. Tay–Sachs Disease
      262. Telomeres: Protection and Maintenance
      263. Thalassemias
      264. Thermosome: A Group II Chaperonin of Archaea
      265. Thiamin Diphosphate and Vitamin B1
      266. Tissue-specific Locus Control: Structure and Function
      267. Titin Gene (TTN)
      268. Transcription Activation in Eukaryotic Cells
      269. The Transcription/DNA Repair Factor TFIIH
      270. Transition States: Substrate-induced Conformational Transitions
      271. Translation of mRNAs in Xenopus Oocytes
      272. Transmembrane Domains
      273. Tubulin and FtsZ Superfamily of Protein Assembly Machines
      274. Tubulin and Microtubules
      275. Two-Component Signalling in Plants
      276. Two-Dimensional Crystallisation of Membrane Proteins and Structural Assessment
      277. Two-dimensional Electron Crystallography
      278. Two-dimensional Gel Electrophoresis
      279. Ubiquitin Pathway
      280. Vitamin K: Structure and Function
      281. Zinc-finger Genes
    13. Replication and Recombination
    14. Sample Preparation in Structural Biology
    15. Signal Transduction
    16. Single Molecule Analysis
    17. Spectrophotometric Methods
    18. Structure of Cell-Cell Interactions
    19. Transcription
    20. Translation and Protein synthesis
    21. Virus Structure and Function
    22. X-Ray Crystallography
  15. Virology

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