eLS

eLS

Online ISBN: 9780470015902

DOI: 10.1002/047001590X

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  1. Biochemistry
  2. Bioethics & Philosophy
  3. Cell Biology
  4. Developmental Biology
  5. Ecology
  6. Evolution & Diversity of Life
  7. Genetics & Disease
  8. Immunology
  9. Microbiology
  10. Molecular Biology
  11. Neuroscience
  12. Plant Science
  13. Science & Society
  14. Structural Biology
    1. Bioinformatics
    2. Cell Motility and Transport
    3. Electron Microscopy
    4. General Structural Biology
    5. Lipids and Membrane Structure
    6. Mass Spectrometry
    7. Membrane Proteins
    8. Nuclear Magnetic Resonance
    9. Nucleic Acid Structure
    10. Optical Microscopy
    11. Protein Folding, Evolution and Degradation
    12. Protein Structure
      1. Actin and Actin Filaments
      2. Actin Reorganization in Nerve Morphogenesis
      3. Amidohydrolase Superfamily
      4. Amino Acid Side-chain Hydrophobicity
      5. Amino Acid Substitutions: Effects on Protein Stability
      6. Aminoacyl-tRNA Synthetases
      7. γ-Aminobutyric Acid (GABA) Receptors
      8. AMPA Receptors
      9. Antibody Classes
      10. Antigen–Antibody Binding
      11. Antitrypsin (AAT) Deficiency-α1
      12. Apolipoprotein Gene Structure and Function
      13. Archaeal Ribosomes
      14. ATP-binding Motifs
      15. Automated Protein Production Technologies
      16. Baculovirus Expression Strategies for Protein Complex Production
      17. BH3-only Proteins
      18. Biological Macromolecules: UV-visible Spectrophotometry
      19. BLAST Algorithm
      20. Blood Group Genetics
      21. Calcium-binding Proteins
      22. Caspases and Cell Death
      23. Caspases, Substrates and Sequential Activation
      24. Catalysis of Disulfide Bond Formation by the Quiescin Sulfhydryl Oxidases
      25. Cell Locomotion
      26. Chaperonins
      27. Chlorophyll-Binding Proteins
      28. Chlorophyll: Structure and Function
      29. Chromatin Recognition Protein Modules: The PHD Finger
      30. Chromatin Remodelling and Histone Modification in Transcription Regulation
      31. Chromosomal Bands and Sequence Features
      32. Chromosomes: Nonhistone Proteins
      33. Circular Dichroism: Studies of Proteins
      34. Cobalamin Coenzymes and Vitamin B12
      35. Coenzymes: Haem
      36. Complement: Terminal Pathways
      37. Cornification of the Skin: A Non-apoptotic Cell Death Mechanism
      38. Cryogenic Detectors: Detection of Single Molecules
      39. Crystallins
      40. Crystallisation of Proteins and Macromolecular Complexes: Past, Present and Future
      41. Crystallization of Protein–DNA Complexes
      42. Crystallization of Proteins: Two-dimensional
      43. Cystatins
      44. Cytoskeleton
      45. Deafness
      46. Death Receptors at the Molecular Level: Therapeutic Implications
      47. Difference Gel Electrophoresis (DIGE)
      48. Direct Labelling of Proteins with 125I
      49. Disordered Proteins
      50. DNA Helicases
      51. DNA Methylation
      52. You have free access to this content
        DNA Replication
      53. DNA-binding Enzymes: Structural Themes
      54. Dynamic Programming
      55. EF-hand Calcium-binding Proteins
      56. Electron Cryomicroscopy and Three-dimensional Computer Reconstruction of Biological Molecules
      57. Electron Paramagnetic Resonance (EPR) and Spin-labelling
      58. EM Analysis of Protein Structure
      59. Engineered Enzymes
      60. Enzyme Activity: Allosteric Regulation
      61. Enzyme Activity: Control
      62. Enzyme Specificity and Selectivity
      63. Enzymes: Phosphopantetheine-dependent
      64. Enzymes: The Active Site
      65. Epitope Mapping: B-cell Epitopes
      66. Erythrocyte Membrane Disorders
      67. Eukaryotic Replication Fork
      68. Eukaryotic Replication Protein A
      69. Evolution of Protein Domains
      70. Exosome Complex
      71. Expression Tags for Protein Production
      72. Fc Receptors
      73. Fibrinogen and Fibrin
      74. Forkhead Domains
      75. From Reactive Oxygen and Nitrogen Species to Therapy
      76. Fusion Proteins as Research Tools
      77. G Protein-Coupled Receptors
      78. G Proteins
      79. Genome, Proteome and the Quest for a Full Structure–Function Description of an Organism
      80. Global Alignment
      81. Globin Genes: Polymorphic Variants and Mutations
      82. Glycoproteins
      83. Glycosidases: Functions, Families and Folds
      84. Glycosylation and Disease
      85. Green Fluorescent Protein (GFP)
      86. GTP-binding Loop
      87. Haem Proteins
      88. Haem Structure and Function
      89. Haemoglobin: Cooperativity in Protein–Ligand Interactions
      90. Hidden Markov Models
      91. Histones: Gene Organisation and Post-translational Modification
      92. History of Protein Chemistry
      93. Hsp90 Chaperones
      94. Hydrogen Bonds in Proteins: Role and Strength
      95. Hydrophobic Interaction Chromatography
      96. Hydrophobicity Plots
      97. Identification of Protein–Protein Interactions
      98. Immunoglobulin Fold: Structures of Proteins in the Immunoglobulin Superfamily
      99. Immunoglobulin Superfamily
      100. Industrialization of Proteomics: Scaling UpProteomics Processes
      101. Inhibitor of Apoptosis (IAP) and BIR-containing Proteins
      102. Integrase Class Site-specific Recombinases
      103. Integrins
      104. Interaction Networks of Proteins
      105. Intermediate Filaments
      106. Intrinsically Disordered Proteins
      107. Iron Cofactors: Nonhaem
      108. Laser Capture Microdissection in Proteomics
      109. Lectins
      110. Leucine Zipper
      111. Leucine Zippers
      112. Light-harvesting Complex
      113. Limits of Proteomics: Protein Solubilisation Issues
      114. Lipoprotein Metabolism: Structure and Function
      115. Luciferases and Light-emitting Accessory Proteins: Structural Biology
      116. Lysozyme
      117. Macromolecular Interactions: Light Scattering
      118. Macromolecular Structure Determination by X-ray Crystallography
      119. Major Histocompatibility Complex (MHC) Genes
      120. Major Histocompatibility Complex: Interaction with Peptides
      121. Mass Spectrometry in Protein Characterization
      122. Mass Spectrometry Instrumentation in Proteomics
      123. Mass Spectrometry: Analysis of Two-dimensional Protein Gels
      124. Mass Spectrometry: Peptide Sequencing
      125. You have free access to this content
        Messenger RNA: Interaction with Ribosomes
      126. Metalloenzymes and Electrophilic Catalysis
      127. Microtubule Organization in Dictyostelium
      128. Molecular Dynamics
      129. Molecular Entry Point: Strategies in Proteomics
      130. Molecular Genetics of the α-Thalassaemias
      131. Molecular Machines and Human Disorders
      132. Molten Globule
      133. Motor Proteins
      134. Multidomain Proteins
      135. Multiple Alignment
      136. Myoglobin
      137. Myosin Superfamily
      138. NAD(P)+ Binding to Dehydrogenases
      139. Nitrogenase Complex
      140. Nuclear Magnetic Resonance (NMR) Spectroscopy: Structure Determination of Proteins and Nucleic Acids
      141. Non-Classical MHC Class I Molecules (MHC-Ib)
      142. Normal Mode Analysis Techniques in Structural Biology
      143. Nuclear Envelope and Lamins: Organization and Dynamics
      144. Nuclear Magnetic Resonance (NMR) of Proteins: Solid State
      145. Nuclear Magnetic Resonance (NMR) Spectroscopy of Proteins
      146. Nucleolar Proteomics
      147. Nucleosomes: Detailed Structure and Mutations
      148. Nucleosomes: Structure and Function
      149. Olfactory Receptors
      150. Pattern Searches in Protein Sequences
      151. Peptidases
      152. Peptide Bonds, Disulfide Bonds and Properties of Small Peptides
      153. Peptide Mapping
      154. Peptide Sequencing by Edman Degradation
      155. Peptides: Biological Activities of Small Peptides
      156. Peptidylproline cistrans-Isomerases
      157. Phosphoproteomics
      158. Photosystem I
      159. Plant Storage Products (Carbohydrates, Oils and Proteins)
      160. Polymerization Dynamics of Cytoskeletal Filaments
      161. Posttranslational Modification and Human Disorders
      162. Posttranslational Processing: Peptide Hormones and Neuropeptide Transmitters
      163. Potassium Channels
      164. Preparation Artefacts in Proteomics: Technological Issues
      165. Primary Protein and Nucleic Acid Three-dimensional Structure Databases
      166. Profile Searching
      167. Proline Residues in Proteins
      168. Protease Complexes
      169. Protein Coding
      170. Protein Databases
      171. Protein Design
      172. Protein Disorder and Human Genetic Disease
      173. Protein Disulfide Isomerases
      174. Protein Domain Fusion
      175. Protein Families: Evolution
      176. Protein Folding In Vivo
      177. Protein Folding: Overview of Pathways
      178. Protein Homology Modelling
      179. Protein Interaction and Genetic Disease
      180. Protein Isoforms and Isozymes
      181. Protein Kinases: Signatures in Cancer
      182. Protein Motifs for DNA Binding
      183. Protein Motifs: the Helix-Loop-Helix Motif
      184. Protein Motifs: the Helix-Turn-Helix Motif
      185. Protein Phosphatases
      186. Protein Quaternary Structure: Subunit–Subunit Interactions
      187. Protein Quaternary Structure: Symmetry Patterns
      188. Protein Secondary Structures: Prediction
      189. Protein Sequence Databases
      190. Protein Stability
      191. Protein Structural Flexibility: Molecular Motions
      192. Protein Structure
      193. Protein Structure Classification
      194. Protein Structure Design and Engineering
      195. Protein Structure Prediction
      196. Protein Structure Prediction and Databases
      197. Protein Structure: Unusual Covalent Bonds
      198. Protein Superfamilies
      199. Protein Synthesis: Measuring Errors
      200. Protein Tertiary Structures: Prediction from Amino Acid Sequences
      201. Protein–DNA Complexes: Nonspecific
      202. Protein–DNA Complexes: Specific
      203. Protein–DNA Interactions
      204. Protein–DNA Interactions: Polyelectrolyte Effects
      205. Protein–DNA Interactions: Structure and Energetics
      206. Protein–DNA Interactions: Techniques Used
      207. Protein–Ligand Interactions: Computational Docking
      208. Protein–Ligand Interactions: Energetic Contributions and Shape Complementarity
      209. Protein–Ligand Interactions: General Description
      210. Protein–Ligand Interactions: Induced Fit
      211. Protein–Nucleic Acid Interaction: Major Groove Recognition Determinants
      212. Protein-Protein Interaction Maps
      213. Protein–Protein Interactions
      214. Protein–protein Interactions: Identification
      215. Protein–RNA Interactions
      216. Proteins: Affinity Tags
      217. Proteins: Fundamental Chemical Properties
      218. Proteins: Mutational Effects in
      219. Proteins: Postsynthetic Modification – Function and Physical Analysis
      220. Proteoglycans
      221. Proteomics: A Molecular Scanner in Medicine
      222. Proteomics: A Shotgun Approach without Two-dimensional Gels
      223. Purifying and Analysing Cytosolic Protein Complexes
      224. Pyruvate Dehydrogenase Complex
      225. Quantitative Proteomics (ICAT™)
      226. Rad51 and Eukaryotic Recombination Proteins
      227. Radical Enzymes
      228. Radical S-adenosylmethionine (SAM) Superfamily
      229. RecA Protein
      230. RecFOR Protein
      231. Regulation by Covalent Modification
      232. Resonance Raman Spectroscopy
      233. Rhodopsin
      234. Ribosomal Proteins in Eukaryotes
      235. Ribosomal Proteins: Structure and Evolution
      236. Ribosomal RNA
      237. Ribosomes and Ribosomal Proteins: More Than Just ‘Housekeeping’
      238. RNA Polymerase II Holoenzyme and Transcription Factors
      239. RNA Polymerases: Subunits and Functional Domains
      240. RNA Synthesis
      241. Sequence Alignment
      242. Sequence Similarity
      243. Serine Proteases
      244. Signal Peptides
      245. Single-stranded DNA-binding Proteins
      246. Smith–Waterman Algorithm
      247. Structural Basis of Disulfide Bond Formation in the Bacterial Periplasm and Mammalian ER
      248. Structural Databases of Biological Macromolecules
      249. Structural Genomics
      250. Structural Predictions and Modeling
      251. Structural Proteomics: Large-scale Studies
      252. Structure and Function of IAP and Bcl-2 Proteins
      253. Structure–Function Relationships in the Aromatic Amino Acid Hydroxylases Enzyme Family: Evolutionary Insights
      254. Structures, Domains and Functions in Cell Death (DD, DED, CARD, PYD)
      255. Synaptic Vesicle Proteins
      256. Tandem Affinity Purification (TAP) Tags
      257. Tay–Sachs Disease
      258. Telomeres: Protection and Maintenance
      259. Thalassemias
      260. Thiamin Diphosphate and Vitamin B1
      261. Tissue-specific Locus Control: Structure and Function
      262. Titin Gene (TTN)
      263. Transcription Activation in Eukaryotic Cells
      264. The Transcription/DNA Repair Factor TFIIH
      265. Transition States: Substrate-induced Conformational Transitions
      266. Translation of mRNAs in Xenopus Oocytes
      267. Transmembrane Domains
      268. Tubulin and FtsZ Superfamily of Protein Assembly Machines
      269. Two-Component Signalling in Plants
      270. Two-dimensional Electron Crystallography
      271. Two-dimensional Gel Electrophoresis
      272. Two-hybrid and Related Systems
      273. 5′-UTRs and Regulation
      274. Vitamin K: Structure and Function
      275. Zinc-finger Genes
    13. Replication and Recombination
    14. Sample Preparation in Structural Biology
    15. Signal Transduction
    16. Single Molecule Analysis
    17. Spectrophotometric Methods
    18. Structure of Cell–Cell Interactions
    19. Transcription
    20. Translation and Protein synthesis
    21. Virus Structure and Function
    22. X-Ray Crystallography
  15. Virology

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