Brain Energetics and Neuronal Activity: Applications to fMRI and Medicine

Copyright © 2004 John Wiley & Sons, Ltd

Brain Energetics and Neuronal Activity: Applications to fMRI and Medicine

Editor(s): Robert G. Shulman, Douglas L. Rothman

Published Online: 18 AUG 2005

Print ISBN: 9780470847206

Online ISBN: 9780470020524

DOI: 10.1002/0470020520

About this Book

Product Information

About The Product

This book is unique in linking in vivo 13C NMR measurements of neuronal activity and energetics with applications to functional imaging and certain disease states It provides a fundamental neurochemical explanation of brain activity applicable to functional imaging, theories of neuronal activity and disease states, e.g. epilepsy, psychiatric diseases and developmental disorders.

  • Novel and potentially controversial
  • Will inspire future research directions

Table of contents

    1. You have free access to this content
      Front Matter (pages i–xii)

    2. Chapter 1

      Introduction (pages 1–9)

      Douglas L. Rothman and Robert G. Shulman

    3. Chapter 2

      Energy Metabolism in Neural Tissues in vivo at Rest and in Functionally Altered States (pages 11–30)

      Louis Sokoloff

    4. Chapter 3

      Techniques–MRS, fMRI, 13C NMR, Indirect Detection of 13C (pages 31–52)

      Robin de Graaf

    5. Chapter 4

      Metabolic Modeling Analysis of Brain Metabolism (pages 53–72)

      Graeme Mason

    6. Chapter 5

      Cerebral Energetics and Neurotransmitter Fluxes (pages 73–97)

      Nicola R. Sibson

    7. Chapter 6

      NMR Studies of the Metabolism and Energetics of GABA Neurotransmitter Pathways (pages 99–110)

      Kevin L. Behar and Douglas L. Rothman

    8. Chapter 7

      Neural Energy Consumption and the Representation of Mental Events (pages 111–124)

      Simon B. Laughlin and David Attwell

    9. Chapter 8

      Imaging Cerebral Metabolic Rate of Oxygen Consumption (CMRO2) Using 17O NMR Approach at Ultrahigh Field (pages 125–146)

      Wei Chen, Xiao-Hong Zhu and Kamil Ugurbil

    10. Chapter 9

      Deriving Changes in CMRO2 from Calibrated fMRI (pages 147–171)

      Fahmeed Hyder

    11. Chapter 10

      Relationship between CMRO2 and Neuronal Activity (pages 173–194)

      Fahmeed Hyder and Hal Blumenfeld

    12. Chapter 11

      NMR Studies of Bioenergetic Impairment in Human Epilepsy (pages 195–213)

      Hoby P. Hetherington, Jullie W. Pan and Dennis D. Spencer

    13. Chapter 12

      MRS Studies of the Role of Altered Glutamate and GABA Neurotransmitter Metabolism in the Pathophysiology of Epilepsy (pages 215–237)

      Ognen A. C. Petroff and Dennis D. Spencer

    14. Chapter 13

      The Role of Altered Energetics of Neurotransmitter Systems in Psychiatric Disease (pages 239–256)

      Graeme F. Mason

    15. Chapter 14

      Long-Term Memory: Do Incremental Signals Reflect Engagement of Cognitive Processes? (pages 257–277)

      Jed A. Meltzer and R. Todd Constable

    16. Chapter 15

      Using fMRI to Study the Mind and Brain (pages 279–293)

      Bruce E. Wexler

    17. Chapter 16

      Brain and Mind: An NMR Perspective (pages 295–309)

      Robert G. Shulman and Fahmeed Hyder

    18. Chapter 17

      The Role of the NMR Baseline Signal in the Study of Consciousness: The Restless Brain (pages 311–314)

      Robert G. Shulman

    19. You have free access to this content
      Index (pages 315–321)

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