The Eicosanoids

The Eicosanoids

Editor(s): Peter Curtis-Prior

Published Online: 13 JUL 2004

Print ISBN: 9780471489849

Online ISBN: 9780470020623

DOI: 10.1002/0470020628

About this Book

This comprehensive reference work, updated from the first edition, brings together the knowledge and expertise of contributors from around the world. It includes new topics such as prostaglandin synthetase enzyme, new synthetic eicosanoids, innovative analytical methods, the influence of cytokines in the regulation of synthesis and actions, newer eicosanoids that influence the cardiovascular system, and newly discovered roles in reproduction and interactions with nitric oxide.

This book satisfies a surge of interest in prostaglandins-NSAIDS (e.g. aspirin) are the biggest selling drugs of all time, and the field has been refreshed by the advent of new types (selective COX-2 inhibitors, anti-leukotiene drugs).

Table of contents

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  1. Part ONE: Biosynthesis and Metabolism

    1. Chapter 1

      Perspectives on the Biosynthesis and Metabolism of Eicosanoids (pages 1–16)

      Robert C. Murphy, Rebecca C. Bowers, Jennifer Dickinson and Karin Zemski Berry

    2. Chapter 5

      Mammalian Lipoxygenases (pages 53–59)

      Shozo Yamamoto, Hiroshi Suzuki, Natsuo Ueda, Yoshitaka Takahashi and Tanihiro Yoshimoto

  2. Part TWO: Analytical Methods

    1. Chapter 11

      Gas Chromatography and Mass Spectrometry in Eicosanoid Analysis (pages 117–121)

      Michinao Mizugaki, Takanori Hishinuma, Naoto Suzuki and Junichi Goto

  3. Part THREE: Biochemical and Molecular Pharmacology

  4. Part FOUR: Immunology, Endocrinology and Metabolic Regulation

  5. Part FIVE: Inflammation

  6. Part SIX: Circulatory System

    1. Chapter 34

      Generation of Vasoactive Prostanoids by the Cyclooxygenase-2 Pathway in the Cardiovascular System of the Rat (pages 387–392)

      P. J. Kadowitz, S. R. Baber, M. M. Mazim, M. Keebler, H. C. Champion, T. J. Bivalacqua, D. B. McNamara and A. L. Hyman

  7. Part SEVEN: Digestive System

  8. Part EIGHT: Nervous System

    1. Chapter 43

      Prostanoids in Pain (pages 473–480)

      Tony L. Yaksh, Patrick W. Mantyh and Camilla I. Svensson

  9. Part NINE: Reproductive System

  10. Part TEN: Conclusions and Correlations

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    1. You have free access to this content