Glycogen Synthase Kinase 3 (GSK-3) and Its Inhibitors: Drug Discovery and Development

Glycogen Synthase Kinase 3 (GSK-3) and Its Inhibitors: Drug Discovery and Development

Editor(s): Ana Martinez, Ana Castro, Miguel Medina

Published Online: 6 MAR 2006

Print ISBN: 9780471770015

Online ISBN: 9780470052174

DOI: 10.1002/0470052171

Series Editor(s): Binghe Wang

About this Book

Many researchers believe that GSK-3 and its inhibitors could lead to effective treatments for neurogenerative disorders, type II diabetes, depression and bipolar disorder, and some forms of cancer. This book provides a thorough introduction to GSK-3, presents up-to-date information, and mentions the birth of several chemical families of GSK-3 inhibitors with varying selectivity. It's a great reference for researchers in drug design and development.

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Part I: Cellular Functions of GSK-3

    1. Chapter 3

      Role of GSK-3/Shaggy in Neuronal Cell Biology (pages 45–60)

      Diana Simón, Olga Varea, Juan José Garrido and Francisco Wandosell

  2. Part II: GSK-3 as a Therapeutic Target in Human Pathology

    1. Chapter 10

      Protein Kinase Assays for Drug Discovery (pages 189–201)

      Miguel Medina, Ana Fuertes, Ester Martín-Aparicio, María del Monte-Millán, María-Luisa Navarro and José Pérez-Puerto

  3. Part III: GSK-3 Inhibitors: Development and Therapeutic Potential

    1. You have free access to this content

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