Pharmacometrics: The Science of Quantitative Pharmacology

Pharmacometrics: The Science of Quantitative Pharmacology

Editor(s): Ene I. Ette, Paul J. Williams

Published Online: 18 MAY 2006

Print ISBN: 9780471677833

Online ISBN: 9780470087978

DOI: 10.1002/0470087978

About this Book

Pharmacometrics is the science of interpreting and describing pharmacology in a quantitative fashion. The pharmaceutical industry is integrating pharmacometrics into its drug development program, but there is a lack of and need for experienced pharmacometricians since fewer and fewer academic programs exist to train them. Pharmacometrics: The Science of Quantitative Pharmacology lays out the science of pharmacometrics and its application to drug development, evaluation, and patient pharmacotherapy, providing a comprehensive set of tools for the training and development of pharmacometricians.

Edited and written by key leaders in the field, this flagship text on pharmacometrics:

  • Integrates theory and practice to let the reader apply principles and concepts.
  • Provides a comprehensive set of tools for training and developing expertise in the pharmacometric field.
  • Is unique in including computer code information with the examples.

This volume is an invaluable resource for all pharmacometricians, statisticians, teachers, graduate and undergraduate students in academia, industry, and regulatory agencies.

Table of contents

    1. You have free access to this content
    2. Chapter 9

      Data Imputation (pages 245–262)

      Ene I. Ette, Hui-May Chu and Alaa Ahmad

    3. Chapter 13

      Population Models for Drug Absorption and Enterohepatic Recycling (pages 345–382)

      Olivier Pétricoul, Valérie Cosson, Eliane Fuseau and Mathilde Marchand

    4. Chapter 31

      Design and Analysis of Clinical Exposure: Response Trials (pages 803–826)

      David Hermann, Raymond Miller, Matthew Hutmacher, Wayne Ewy and Kenneth Kowalski

    5. Chapter 35

      Clinical Trial Simulation: Efficacy Trials (pages 881–900)

      Matthew M. Riggs, Christopher J. Godfrey and Marc R. Gastanguay

    6. You have free access to this content

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