Sodium Channels and Neuronal Hyperexcitability: Novartis Foundation Symposium 241

Sodium Channels and Neuronal Hyperexcitability: Novartis Foundation Symposium 241

Editor(s): Gregory Bock, Jamie A. Goode

Published Online: 7 OCT 2008

Print ISBN: 9780471485308

Online ISBN: 9780470846681

DOI: 10.1002/0470846682

Series Editor(s): Novartis Foundation

About this Book

Recent progress has led to a better understanding of the molecular structure of sodium channels, how they work and the mechanisms that restrict their expression to particular cell types.

This book explains how these channels are modulated in various pathological states to enable the development of therapeutic strategies based on sodium channel restoration.

The authors present the most current research on sodium channels and neuronal function.

  • Brings together both the basic biology and biophysics with detailed consideration of the medical applications in chronic pain and epilepsy.
  • Includes coverage of channelopathies, sodium channel gene expression, the modulation of sodium channels, and molecular mechanisms of gating and drug block of sodium channels.

Table of contents

    1. You have free access to this content
    2. Mutations of Voltage-gated Sodium Channels in Movement Disorders and Epilepsy (pages 72–86)

      Miriam H. Meisler, Jennifer A. Kearney, Leslie K. Sprunger, Bryan T. MacDonald, David A. Buchner and Andrew Escayg

    3. Sodium Channels in Primary Sensory Neurons: Relationship to Pain States (pages 159–172)

      John N. Wood, Armen N. Akopian, Mark Baker, Yanning Ding, Fleur Geoghegan, Mohammed Nassar, Misbah Malik-Hall, Kenji Okuse, Louisa Poon, Samantha Ravenall, Madhu Sukumaran and Veronika Souslova

    4. You have free access to this content

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