Role Of The Sarcoplasmic Reticulum In Smooth Muscle: Novartis Foundation Symposium 246

Role Of The Sarcoplasmic Reticulum In Smooth Muscle: Novartis Foundation Symposium 246

Editor(s): Derek J. Chadwick, Jamie A. Goode

Published Online: 7 OCT 2008

Print ISBN: 9780470844793

Online ISBN: 9780470853054

DOI: 10.1002/0470853050

Series Editor(s): Novartis Foundation

About this Book

Smooth muscle contraction is a vital component of the functioning of blood vessels, the uterus, airways and the bladder. Its malfunction can lead to serious pathological conditions, such as hypertension and pre-term labour. The calcium ion plays a central role in smooth muscle function, increasing in concentration for contraction and decreasing for relaxation. Calcium entry into the cell is facilitated by the sarcoplasmic reticulum (SR).

This book explores the latest research on the role of the sarcoplasmic reticulum (SR) in smooth muscle function. It examines the control and modulation of the SR and how this may vary among smooth muscle types. Potential therapeutic implications are also discussed.

  • Discusses new and exciting work in this area and identifies promising new research directions.
  • Considers the advances in this relatively unexplored field, offering new insights into the role of the SR muscle.
  • Brings together contributions from key workers, both in basic and clinical science, whose studies range from physiological to pathological and molecular to whole animal.


     

Table of contents

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    2. Organization of Ca2+ Stores in Vascular Smooth Muscle: Functional Implications (pages 125–141)

      Mordecai P. Blaustein, Vera A. Golovina, Hong Song, Jacqueline Choate, Lubomira Lencesova, Shawn W. Robinson and W. Gil Wier

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    4. You have free access to this content

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