Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine

Metallotherapeutic Drugs and Metal-Based Diagnostic Agents: The Use of Metals in Medicine

Editor(s): Marcel Gielen, Edward R.T. Tiekink

Published Online: 20 DEC 2005

Print ISBN: 9780470864036

Online ISBN: 9780470864050

DOI: 10.1002/0470864052

About this Book

There are an astonishing number and variety of roles that metals play in contemporary medicine. This book contains information on the medicinal uses of inorganics, that is, of elements such as boron, lithium, selenium, to name a few, as well as metal-containing species.

In keeping with the notion that healthy mammals rely on (bio-essential) metals for the normal functioning of approximately a third of their proteins and enzymes, a large number of drugs are metal-based and considerable effort is being devoted to developing both second- and third-generation drugs as well as generating novel metal-based drugs. While there is no doubt that there is an emphasis on 'Metallotherapeutics' throughout the volume, the use of metals in medicine is not restricted to metal-based drugs. The following are also covered:

  • non-invasive radiopharmaceuticals
  • Magnetic Resonance Imaging (MRI)
  • mineral supplements

Table of contents

    1. You have free access to this content
    2. You have free access to this content
    3. Chapter 2

      5B Boron Compounds as Therapeutic Drugs (pages 19–49)

      Geeta Rana, Kamesh Vyakaranam, John A. Maguire and Narayan S. Hosmane

    4. Chapter 9

      25Mn Manganese Metallotherapeutics (pages 159–178)

      Jeanne H. Freeland-Graves, Tanushree Bose and Abbass Karbassian

    5. Chapter 19

      44Ru Perspectives of Ruthenium Complexes in Cancer Therapy (pages 359–378)

      Olivier Lentzen, Cécile Moucheron and Andrée Kirsch-De Mesmaeker

    6. Chapter 21

      46Pd The Use of Palladium Complexes in Medicine (pages 399–419)

      Achilleas Garoufis, Sotiris K. Hadjikakou and Nick Hadjiliadis

    7. Chapter 28

      Paramagnetic Metal Complexes As Contrast Agents for Magnetic Resonance Imaging (pages 541–560)

      Silvio Aime, Alessandro Barge, Eliana Gianolio, Simonetta Geninatti Crich, Walter Dastrú and Fulvio Uggeri

    8. You have free access to this content

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