Neuronal and Cognitive Effects of Oestrogens: Novartis Foundation Symposium 230

Neuronal and Cognitive Effects of Oestrogens: Novartis Foundation Symposium 230

Editor(s): Derek J. Chadwick, Jamie A. Goode

Published Online: 29 APR 2008

Print ISBN: 9780471492030

Online ISBN: 9780470870815

DOI: 10.1002/0470870818

Series Editor(s): Novartis Foundation

About this Book

Although normally thought of as a sex hormone, recent research has highlighted the numerous and significant effects that oestrogen has on the CNS, extending far beyond its important reproductive role. It has been shown that oestrogen acts as a neural growth factor with important influences on the survival, plasticity, regeneration and ageing of the mammalian brain.

This exciting book brings together leading clinicians and researchers to discuss oestrogen's basic mechanisms of action, the extrahypothalmic brain regions it affects, and its influence on cognitive functions in animals and humans. Finally, recent research on the role of oestrogens in ageing and dementia, including the significance of oestrogen action in Alzheimer's disease, is discussed. The 15 papers contained in this book, together with the extensive discussion sessions that follow them, reveal much new and exciting work in this area, and identify promising new research directions.

Table of contents

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    2. Oestrogen Receptor Function at Classical and Alternative Response Elements (pages 20–32)

      Peter J. Kushner, David Agard, Wei-Jun Feng, Gabriela Lopez, Andrew Schiau, Rosalie Uht, Paul Webb and Geoffrey Greene

    3. Oestrogen Modulation of Noradrenaline Neurotransmission (pages 74–93)

      Allan E. Herbison, Sharon X. Simonian, Niren R. Thanky and R. John Bicknell

    4. Oestrogen Effects in Olivo-Cerebellar and Hippocampal Circuits (pages 155–172)

      Sheryl S. Smith, Fu-Chun Hsu, Xinshe Li, Cheryl A. Frye, Donald S. Faber and Ronald S. Markowitz

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