Neural Transplantation in Neurodegenerative Disease: Current Status and New Directions: Novartis Foundation Symposium 231

Neural Transplantation in Neurodegenerative Disease: Current Status and New Directions: Novartis Foundation Symposium 231

Editor(s): Derek J. Chadwick, Jamie A. Goode

Published Online: 7 OCT 2008

Print ISBN: 9780471492467

Online ISBN: 9780470870839

DOI: 10.1002/0470870834

Series Editor(s): Novartis Foundation

About this Book

The field of neural transplantation is at a crucial stage, with  important clinical trials on transplantation in patients with Parkinson's disease nearing completion and novel, alternative approaches to fetal transplantation being developed.

This timely book brings together leading neuroscientists, clinicians, and cell and developmental biologists to discuss the use of neural transplants in neurodegenerative disorders, such as Parkinson's disease, Huntington's chorea, amyotrophic lateral sclerosis, multiple sclerosis and spinal cord injury. There is also extensive coverage of the potential alternatives to freshly derived fetal tissue as the source of transplants, for example xenografts, encapsulated cells and immortalized stem cells. With authoritative contributions and lively discussion sections, this book presents much new and exciting work in this field and identifies promising new research directions.

Table of contents

    1. You have free access to this content
    2. Functional Reconstruction of the Hippocampus: Fetal Versus Conditionally Immortal Neuroepithelial Stem Cell Grafts (pages 53–69)

      H. Hodges, P. Sowinski, D. Virley, A. Nelson, T. R. Kershaw, W. P. Watson, T. Veizovic, S. Patel, A. Mora, T. Rashid, S. J. French, A. Chadwick, J. A. Gray and J. D. Sinden

    3. Transplantation of Human Fetal Striatal Tissue in Huntington's Disease: Rationale for Clinical Studies (pages 129–144)

      Thomas B. Freeman, Robert A. Hauser, Alison E. Willing, Tanja Zigova, Paul R. Sanberg and Samuel Saporta

    4. Neural Stem Cells Are Uniquely Suited for Cell Replacement and Gene Therapy in the CNS (pages 242–269)

      Vaclav Ourednik, Jitka Ourednik, Kook I. Park, Y. D. Teng, Karen A. Aboody, Kurtis I. Auguste, Rosanne M. Taylor, Barbara A. Tate and Evan Y. Snyder

    5. Functional Repair with Neural Stem Cells (pages 270–288)

      John D. Sinden, Paul Stroemer, Gregory Grigoryan, Sara Patel, Sarah J. French and Helen Hodges

    6. You have free access to this content
    7. You have free access to this content

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