Current Protocols in Pharmacology

Mission Statement

Sound and reproducible laboratory methods are the foundation of scientific discovery. Yet, all too often, nuances that are critical for an experiment’s success are not captured in the primary literature but exist only as part of a lab’s oral tradition. The aim of each Current Protocols title is to provide the clearest, most detailed and reliable step-by-step instructions for all protocols relevant to a given subject area. Written by experts in the field and extensively edited to our exacting standards, each article also provides invaluable discussions of background information, applications of the methods, important assumptions, key parameters, troubleshooting tips, time considerations, and more. Furthermore, Current Protocols content is thoughtfully organized by topic for optimal usage and to maximize contextual knowledge. Quarterly installments allow Current Protocols to constantly evolve to keep pace with the newest discoveries and developments.

Current Protocols in Pharmacology is the comprehensive resource for all types of experiments pertaining to drug discovery and pharmacology. Current Protocols in Pharmacology brings together hundreds of core and cutting edge techniques in all areas of drug discovery, including receptor binding and localization, signal transduction, enzyme assays, molecular biology, pharmacokinetics, safety pharmacology/toxicology, electrophysiology, anti-infectives, and a vast array of animal, isolated tissue, and cellular models. Numerous informative overviews are also provided to describe the progression and challenges of the drug discovery and development process, in addition to primers on safety pharmacology issues, designing receptor binding and isolated tissue assays, cell culture techniques, electrophysiological methods, chemical diversity, allosterism, high throughput screening, pharmacogenetics, signal transduction, and more. Updated quarterly, Current Protocols in Pharmacology constantly evolves to keep pace with the newest discoveries and developments.

The target audience is the researcher working in the areas of drug discovery and pharmacology, with the level of sophistication geared to the novice experimenter—the new laboratory technician or experienced investigator branching out into a new area of research. Exquisite detail is provided to permit duplication of the protocols in any laboratory, whatever the disciplinary background or level of sophis¬tication.

Readership

Pharmaceutical scientists • Pharmacologists • toxicologists • medicinal chemists • biochemists • specialists in drug evaluation, approval, and regulation

Keywords

Drug discovery, pharmacology, pharmaceutical technology, neuropharmacology, cardiovascular pharmacology, safety pharmacology, drug delivery, medicinal chemistry, pharmacokinetics, ADME, electrophysiology, receptor, receptor binding, animal models, laboratory protocols, Current Protocols