Current Protocols in Nucleic Acid Chemistry

What's New

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Supplement 48, March 2012

Unit 4.48 Synthesis and Application of Highly Reactive Amino Linkers for Functional Oligonucleotides
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Unit 4.49 Oligodeoxynucleotide Containing S-Functionalized 2′-Deoxy-6-Thioguanosine: Facile Tools for Base-Selective and Site-Specific Internal Modification of RNA
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Unit 12.9 DNA Origami: Synthesis and Self-Assembly
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Unit 14.8 One-Flask Synthesis of Cyclic Diguanosine Monophosphate (c-di-GMP)
         Abstract | Full Text:  HTML   PDF

Unit 16.4 Synthesis of Dumbbell-Shaped Cyclic RNAs for RNA Interference
         Abstract | Full Text:  HTML   PDF

Coming Soon

Two-Step, One-Pot Synthesis of Inosine, Guanosine, and 2′ -Deoxyguanosine O⁶-Ethers

Aqueous-Phase Sonogashira Alkynylation to Synthesize 5-Substituted Pyrimidine and 8-Substituted Purine Nucleosides

Safe Deprotection Strategy for the Tert-Butyldimethylsilyl (TBS) Group During RNA Synthesis

Attachment of Nitroxide Spin Labels to Nucleic Acids for EPR

Purification of Synthetic Oligonucleotides via Catching by Polymerization

Gram-Scale Chemical Synthesis of 2′-Deoxynucleoside-5′-O-Triphosphates