Current Protocols in Human Genetics

Mission Statement

Sound and reproducible laboratory methods are the foundation of scientific discovery. Yet, all too often, nuances that are critical for an experiment’s success are not captured in the primary literature but exist only as part of a lab’s oral tradition. The aim of each Current Protocols title is to provide the clearest, most detailed and reliable step-by-step instructions for all protocols relevant to a given subject area. Written by experts in the field and extensively edited to our exacting standards, each article also provides invaluable discussions of background information, applications of the methods, important assumptions, key parameters, troubleshooting tips, time considerations, and more. Furthermore, Current Protocols content is thoughtfully organized by topic for optimal usage and to maximize contextual knowledge. Quarterly installments allow Current Protocols to constantly evolve to keep pace with the newest discoveries and developments.

Current Protocols in Human Genetics is the comprehensive resource for all types of research and clinical laboratory approaches pertaining to human genetics. Current Protocols in Human Genetics brings together hundreds of core and cutting edge techniques in all branches of genetics such as disease gene mapping, large scale molecular cloning methods, expression analysis, clinical genetics, linkage and association studies, analysis of sequence variants and larger-scale genomic structure, cytogenetics, gene therapy approaches, forensic genetics and biochemical genetics. Current Protocols in Human Genetics offers methods ranging from basic to sophisticated—many of them equally applicable to other eukaryotic organisms, such as the mouse. It also includes valuable appendices, providing basic methodologies such as “Commonly Used Techniques” (e.g., molecular biology and cell culture methods, basic mouse handling techniques, basic statistics ). Updated quarterly, Current Protocols in Human Genetics constantly evolves to keep pace with the newest discoveries and developments.

The target audience for Current Protocols in Human Genetics is the novice or experienced experimenter—the first-year graduate student or seasoned investigator who wants to branch out into a new area of research. Sufficient detail is provided to permit use of the protocols in any laboratory, whatever the disciplinary background or level of sophistication.

Readership

Geneticists • molecular biologists • cytogeneticists • population geneticists • clinical biochemical geneticists• gene therapy researchers • molecular forensic scientists

Keywords

Genetics, medical genetics, cytogenetics, chromosome, genetic testing , clinical genetics, biochemical genetics, cancer genetics, clinical molecular genetics, molecular cytogenetics, molecular forensics, gene therapy, model organisms, mapping, laboratory protocols, Current Protocols