Current Protocols in Bioinformatics

Mission Statement

Sound and reproducible laboratory methods are the foundation of scientific discovery. Yet, all too often, nuances that are critical for an experiment’s success are not captured in the primary literature but exist only as part of a lab’s oral tradition. The aim of each Current Protocols title is to provide the clearest, most detailed and reliable step-by-step instructions for all protocols relevant to a given subject area. Written by experts in the field and extensively edited to our exacting standards, each article also provides invaluable discussions of background information, applications of the methods, important assumptions, key parameters, troubleshooting tips, time considerations, and more. Furthermore, Current Protocols content is thoughtfully organized by topic for optimal usage and to maximize contextual knowledge. Quarterly installments allow Current Protocols to constantly evolve to keep pace with the newest discoveries and developments.

Current Protocols in Bioinformatics is the comprehensive resource for all types of protocols in bioinformatics, enabling the life scientist to become "fluent" in bioinformatics and master the exciting new frontiers opened up by the advent of large-scale, genome-wide, high-throughput technologies. Current Protocols in Bioinformatics features step-by-step instructions for working with hundreds of applications and databases, written by bioinformatics experts from throughout the world. The publication covers approaches such as the effective use of key biological databases, molecular modeling, determining homology, inferring evolutionary relationships, deducing gene structure, building databases, analyzing molecular interactions, predicting RNA structure, using proteomic techniques, and much more.

The target audience for Current Protocols in Bioinformatics is anyone who is interested in applying bioinformatic techniques to their own research questions, and no prior experience in the field is assumed. Protocols are written in sufficient detail so that readers can easily follow and perform the analyses described in Current Protocols in Bioinformatics on their own, making it the ideal companion for experimentalists in all biological disciplines.

Readership

molecular biologists • biologists • bioinformaticians • geneticists • computational biologists • computational biology • computational chemists • structural biologists • evolutionary biologists

Keywords

bioinformatics, genes, computational chemistry, homology, DNA sequence, proteins, structure-function, proteomics, databases, phylogeny, laboratory protocols, Current Protocols