Absorption and Drug Development: Solubility, Permeability, and Charge State
Copyright © 2003 John Wiley & Sons, Inc.
Author(s): Alex Avdeef
Published Online: 8 OCT 2003
Print ISBN: 9780471423652
Online ISBN: 9780471450269
About this Book
Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules:
- Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars.
- Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.