Absorption and Drug Development: Solubility, Permeability, and Charge State

Absorption and Drug Development: Solubility, Permeability, and Charge State

Author(s): Alex Avdeef

Published Online: 8 OCT 2003

Print ISBN: 9780471423652

Online ISBN: 9780471450269

DOI: 10.1002/047145026X

About this Book

Many times drugs work fine when tested outside the body, but when they are tested in the body they fail. One of the major reasons a drug fails is that it cannot be absorb by the body in a way to have the effect it was intended to have. Permeability, Solubility, Dissolution, and Charged State of Ionizable Molecules:

  • Helps drug discovery professionals to eliminate poorly absorbable molecules early in the drug discovery process, which can save drug companies millions of dollars.
  • Extensive tabulations, in appendix format, of properties and structures of about 200 standard drug molecules.

Table of contents

SEARCH