Drug Discovery and Development, Volume 1
Copyright © 2006 John Wiley & Sons, Inc.
Editor(s): Mukund S. Chorghade
Published Online: 16 JUN 2006
Print ISBN: 9780471398486
Online ISBN: 9780471780106
About this Book
This two volume set provides a comprehensive account of the entire sequence of operations involved in discovering a drug through the actual delivery of the drug to clinicians and medical practitioners.
- Includes case studies of the discovery of erythromycin analogs (antibiotics), Tagamet, and Ultiva (remifentanil)
- Discusses the discovery of agents for the treatment and management of bacterial infections, Parkinson's disease, psoriasis, ulcers and stomach pain, atopic dermatitis, asthma, and cancer
- Contains chapters on combinatorial chemistry, molecular biology-based drug discovery, genomics, and chemogenomics
The first volume of this set thoroughly describes conceptualizing a drug, creating a library of candidates for testing, screening those candidates for in vitro and in vivo activity, conducting and analyzing the results of clinical trials, and revising the drug as necessary.