Apoptosis and Autoimmunity

Apoptosis and Autoimmunity

Editor(s): Joachim R. Kalden, Martin Herrmann

Published Online: 16 SEP 2004

Print ISBN: 9783527304424

Online ISBN: 9783527601455

DOI: 10.1002/3527601457

About this Book

This is the first comprehensive book about the relationship between apoptosis and autoimmune diseases.
It offers a unique up-to-date overview on research results on the defective execution of apoptosis and the incomplete clearance of apoptotic cells. The molecular and cellular mechanisms involved are described in detail. As a possible consequence of apoptotic dysfunction, the development of severe autoimmune diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus) is discussed. An outlook on future research topics includes the evaluation of novel therapeutic strategies.

Table of contents

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  1. Part 1: General Features of Apoptosis

  2. Part 2: Clearance of Apoptotic Cells

    1. Chapter 3

      Anti-Inflammatory and Immunoregulatory Effects of Apoptotic Cells (pages 37–56)

      Reinhard E. Voll, Dr. Dr. Martin Herrmann, Irute Girkontaite, Christian Stach, Wasilis Kolowos and Prof. Dr. Dr. Joachim R. Kalden

  3. Part 3: Autoimmunity Caused by Defective Execution of Apoptosis or Defective Clearance of Apoptotic Cells

    1. Chapter 8

      Autoimmune Lymphoproliferative Syndromes (ALPS) (pages 133–155)

      Frédéric Rieux-Laucat, Françoise Deist and Alain Fischer

    2. Chapter 11

      Systemic Lupus Erythematosus (pages 187–204)

      Thomas D. Beyer, Susanne Kuenkele, Udo S. Gaipl, Wasilis Kolowos, Reinhard E. Voll, Irith Baumann, Prof. Dr. Dr. Joachim R. Kalden and Dr. Dr. Martin Herrmann

  4. Part 4: Immunogenicity of Apoptotic Cells

  5. Part 5: “Altered Self” in Dying Cells

  6. Part 6: The Role of DNA Binding Proteins for Systemic Autoimmunity

    1. You have free access to this content
    1. You have free access to this content