Bioinformatics - From Genomes to Drugs

Bioinformatics - From Genomes to Drugs

Editor(s): Thomas Lengauer

Published Online: 1 APR 2004

Print ISBN: 9783527299881

Online ISBN: 9783527601486

DOI: 10.1002/3527601481

Series Editor(s): Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

About this Book

Bioinformatics - the use of computers to retrieve, process, analyze and simulate biological information - promises to revolutionize the process of drug discovery and development. This book provides a broad, application-oriented overview of this technology. Contributions by internationally renowned specialists in the field afford a detailed insight into single bioinformatics components and algorithmic methods. In addition, the state-of-the-art in bioinformatics is evaluated equally from a global view by introducing real application scenarios such as genome projects that require the use of a whole set of bioinformatics tools.

The profound knowledge on bioinformatics presented here not only enables readers to go beyond a mere push-button approach to using bioinformatics software and interpreting the data generated appropriately. It is also essential to assess the potential and limitations of today's bioinformatics software and future challenges. Directed to all those involved in the use or development of new bioinformatics tools - scientists and managers from the fields of molecular biotechnology, pharmaceutics, and medicinal chemistry - this book will lead one step further on the way to rational drug design

Table of contents

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  1. Part I: Basic Technologies

    1. Chapter I-6

      Protein Structure Prediction (pages 237–313)

      Prof. Dr. Ralf Zimmer and Prof. Dr. Thomas Lengauer

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  2. Part II: Applications

    1. Chapter II-3

      Analysis of Sequence Variations (pages 49–68)

      Dr. Christopher S. Carlson, Dr. Mark J. Rieder and Prof. Deborah A. Nickerson

    2. Chapter II-4

      Proteome Analysis (pages 69–118)

      Dr. Pierre-Alain Binz, Dr. Elisabeth Gasteiger, Dr. Jean-Charles Sanchez, Dr. Amos Bairoch, Prof. Dr. Denis F. Hochstrasser and Prof. Ron D. Appel

    3. Chapter II-5

      Target Finding in Genomes and Proteomes (pages 119–135)

      Dr. Stefanie Fuhrman, Dr. Shoudan Liang, Dr. Xiling Wen and Dr. Roland Somogyi

    4. Chapter II-6

      Screening of Drug Databases (pages 137–170)

      Dr. Martin Stahl, Dr. Matthias Rarey and Prof. Gerhard Klebe

    1. You have free access to this content
    1. You have free access to this content