Protein Synthesis and Ribosome Structure: Translating the Genome

Protein Synthesis and Ribosome Structure: Translating the Genome

Editor(s): Knud H. Nierhaus, Daniel N. Wilson

Published Online: 20 JAN 2006

Print ISBN: 9783527306381

Online ISBN: 9783527603435

DOI: 10.1002/3527603433

About this Book

Knud Nierhaus, who has studied the ribosome for more than 30 years, has assembled here the combined efforts of several scientific disciplines into a uniform picture of the largest enzyme complex found in living cells, finally resolving many decades-old questions in molecular biology.
In so doing he considers virtually all aspects of ribosome structure and function -- from the molecular mechanism of different ribosomal ribozyme activities to their selective inhibition by antibiotics, from assembly of the core particle to the regulation of ribosome component synthesis. The result is a premier resource for anyone with an interest in ribosomal protein synthesis, whether in the context of molecular biology, biotechnology, pharmacology or molecular medicine.

Table of contents

    1. You have free access to this content
    2. Chapter 3

      Ribosome Assembly (pages 85–143)

      Prof. Dr. Knud H. Nierhaus and Denis L. Lafontaine

    3. Chapter 4

      tRNA and Synthetases (pages 145–184)

      Viter Marquéz, Prof. Dr. Knud H. Nierhaus, Luís Ribas de Pouplana and Pauls Schimmel

    4. Chapter 7

      Initiation of Protein Synthesis (pages 219–322)

      Dr. Daniel N. Wilson, Alan G. Hinnebusch, Thomas E. Dever and Nahum Sonenberg

    5. Chapter 10

      The Mechanism of Recoding in Pro- and Eukaryotes (pages 397–428)

      Elizabeth S. Poole, Louise L. Major, Andrew G. Cridge and Warren P. Tate

    6. Chapter 11

      Regulation of Ribosome Biosynthesis in Escherichia coli (pages 429–448)

      Madina Iskakova, Sean R. Connell and Prof. Dr. Knud H. Nierhaus

    7. You have free access to this content