Handbook of ATPases: Biochemistry, Cell Biology, Pathophysiology
Copyright © 2004 Wiley-VCH Verlag GmbH & Co. KGaA
Editor(s): Masamitsu Futai, Yoh Wada, Jack H. Kaplan
Published Online: 6 DEC 2005
Print ISBN: 9783527306893
Online ISBN: 9783527606122
About this Book
ATP-dependent active ion transport enables cells to regulate their pH value and to control their ion composition. The reverse process, transforming an ion imbalance into chemical energy, drives mitochondrial and chloroplast ATP synthesis. The mediators of these fundamental processes are ion-motive ATPases, highly conserved enzymes that play key roles in cell physiology from bacteria to man.
As the first comprehensive overview of this important class of enzymes, this handbook summarizes recent knowledge about the molecular mechanism of ATPases, relating this information to the physiology and pathopyhsiology of ion transport, mitochondrial function, vesicle transport and lysosomal acidification. All important P-type, F-type and V-type ATPases are treated systematically, complemented by a special section on the cell biology and physiology of acidic compartments, and backed by an extensive bibliography and index.
This premier reference source for physiologists, molecular biologists, biophysicists and clinical researchers contains contributions by the world's foremost ATPase research groups.