Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Autoantibodies and Autoimmunity: Molecular Mechanisms in Health and Disease

Editor(s): K. Michael Pollard

Published Online: 31 MAY 2006

Print ISBN: 9783527311415

Online ISBN: 9783527607853

DOI: 10.1002/3527607854

About this Book

This is the first book to address all aspects of the biology of autoantibodies in a single volume, including a discussion of immunology, experimental models, clinical aspects, and the use of autoantibodies as probes in molecular and cellular biology.
The editor, currently professor at the W.M. Keck Autoimmune Disease Center of The Scripps Research Institute, has assembled an all-star team of authors to report on the latest research, technologies, and applications. Following an introductory chapter, the book goes on to cover such topics as cellular mechanisms of autoantibody production, clinical and diagnostic usefulness in human disease, and animal models used to study the elicitation of autoantibodies. The whole is rounded off with a look at future perspectives.
With its comprehensive coverage, this volume will appeal not only to immunologists and clinicians but also to cell and molecular biologists.

Table of contents

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  1. Part 1: Introductory Chapters

  2. Part 1: Introductory Chapter

  3. Part 2: Autoimmunity

    1. Chapter 7

      Self-antigen Modification and Autoimmunity (pages 139–156)

      Stuart M. Levine, Livia Casciola-Rosen and Antony Rosen

  4. Part 3: Autoantibodies as Diagnostic Markers

  5. Part 4: Autoantibodies as Molecular and Cellular Probes

    1. Chapter 20

      Autoantibody Recognition of Functional Sites (pages 473–491)

      Carlo Selmi, Sabine Oertelt, Pietro Invernizzi, Mauro Podda and M. Eric Gershwin

  6. Part 5: Autoantibodies in Experimental Models of Autoimmunity

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