Analogue-based Drug Discovery
Copyright © 2006 Wiley-VCH Verlag GmbH & Co. KGaA
Editor(s): János Fischer, C. Robin Ganellin
Published Online: 22 MAY 2006
Print ISBN: 9783527312573
Online ISBN: 9783527608003
About this Book
About The Product
The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds.
Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them.
The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.