Analogue-based Drug Discovery

Analogue-based Drug Discovery

Editor(s): János Fischer, C. Robin Ganellin

Published Online: 22 MAY 2006

Print ISBN: 9783527312573

Online ISBN: 9783527608003

DOI: 10.1002/3527608001

About this Book

The first authoritative overview of past and current strategies for successful drug development by analog generation, this unique resource spans all important drug classes and all major therapeutic fields, including histamine antagonists, ACE inhibitors, beta blockers, opioids, quinolone antibiotics, steroids and anticancer platinum compounds.
Of the 19 analog classes presented in detail, 9 are described by the scientists who discoverd them.
The book includes a table of the most successful drug analogs as based on the IMS ranking and compares them in terms of chemical structure, mode of action and patentability.

Table of contents

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  1. Part I: General Aspects of Analogue-Based Drug Discovery

  2. Part II: Selected Examples Analogue-Based Drug Discoveries

  3. Part II: Selected Examples of Analogue-Based Drug Discoveries

  4. Part II: Selected Examples of Analogue-Based Drug Discoveres

  5. Part III: Table of Selected Analogue Classes

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