Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology

Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology

Author(s): Prof. José Luis Millán

Published Online: 22 MAY 2006

Print ISBN: 9783527310791

Online ISBN: 9783527608065

DOI: 10.1002/3527608060

About this Book

A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers:

* The structure, regulation and expression of the AP genes
* The three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes
* The phenotypic abnormalities of the different AP knockout mice
* Our current understanding of the in vivo role of the AP isozymes.

The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.

Table of contents

    1. You have free access to this content
  1. Part I: Gene and Protein Structure

  2. Part II: In Vivo Functions

  3. Part III: AP Expression in Health and Disease

  4. Part IV: Uses of APs in Industry and Biotechnology

    1. You have free access to this content
    1. You have free access to this content

SEARCH