Voltage-Gated Ion Channels as Drug Targets, Volume 29

Voltage-Gated Ion Channels as Drug Targets, Volume 29

Editor(s): David J. Triggle, Murali Gopalakrishnan, David Rampe, Wei Zheng

Published Online: 6 JUN 2006

Print ISBN: 9783527312580

Online ISBN: 9783527608140

DOI: 10.1002/3527608141

Series Editor(s): Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

About this Book

Edited by the most prominent person in the field and top researchers at US pharmaceutical companies, this is a unique resource for drug developers and physiologists seeking a molecular-level understanding of ion channel pharmacology.
After an introduction to the topic, the authors evaluate the structure and function of ion channels, as well as related drug interaction. A section on assay technologies is followed by a section each on calcium, sodium and potassium channels. Further chapters cover genetic and acquired channelopathies, before the book closes with a look at safety issues in ion channel drug development.
For medicinal and pharmaceutical chemists, biochemists, molecular biologists and those working in the pharmaceutical industry.

Table of contents

    1. You have free access to this content
    1. Chapter 1

      Introduction – On Ion Channels (pages 1–5)

      Dr. Murali Gopalakrishnan, Dr. David Rampe, Prof. David Triggle and Dr. Wei Zheng

  1. Part 5: Calcium Channels

  2. Part 6: Sodium Channels

  3. Part 7: Potassium Channels

    1. Chapter 7.2

      Kv1.3 Potassium Channel: Physiology, Pharmacology and Therapeutic Indications (pages 214–274)

      K. George Chandy, Heike Wulff, Christine Beeton, Peter A. Calabresi, George A. Gutman and Michael Pennington

  4. Part 8: Genetic and Acquired Channelopathies

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