Proteomics in Drug Research

Proteomics in Drug Research

Editor(s): Michael Hamacher, Katrin Marcus, Kai Stühler, André van Hall, Bettina Warscheid, Helmut E. Meyer

Published Online: 6 JUN 2006

Print ISBN: 9783527312269

Online ISBN: 9783527608232

DOI: 10.1002/3527608230

Series Editor(s): Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

About this Book

From skillful handling of the wide range of technologies to successful applications in drug discovery -- this handbook has all the information professional proteomics users need.
Edited by experts working at one of the hot spots in European proteomic research, the numerous contributions by experts from the pharmaceutical industry and public proteomics consortia to provide the necessary perspective on current trends and developments in this exciting field.
Following an introductory chapter, the book moves on to proteomic technologies, such as protein biochips, protein-protein interactions, and proteome analysis in situ. The section on applications includes bioinformatics, Alzheimer's disease, neuroproteomics, plasma and T-cell proteomics, differential phosphoproteome analysis and biomarkers, as well as pharmacogenomics.
Invaluable reading for medicinal and pharmaceutical chemists, gene technologists, molecular biologists, and those working in the pharmaceutical industry.

Table of contents

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  1. Part I: Introduction

    1. Chapter 2

      Proteomic Data Standardization, Deposition and Exchange (pages 19–30)

      Sandra Orchard, Henning Hermjakob, Manuela Pruess and Rolf Apweiler

  2. Part II: Proteomic Technologies

    1. Chapter 6

      Peptidomics Technologies and Applications in Drug Research (pages 113–135)

      Michael Schrader, Petra Budde, Horst Rose, Norbert Lamping, Peter Schulz-Knappe and Hans-Dieter Zucht

  3. Part III: Applications

    1. Chapter 10

      From Target to Lead Synthesis (pages 187–207)

      Stefan Müllner, Holger Stark, Päivi Niskanen, Erich Eigenbrodt, Sybille Mazurek and Hugo Fasold

    2. Chapter 15

      Proteomics in Alzheimer's Disease (pages 279–297)

      Michael Fountoulakis, Sophia Kossida and Gert Lubec

  4. Part IV: To the Market

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