Handbook of Meningococcal Disease: Infection Biology, Vaccination, Clinical Management

Handbook of Meningococcal Disease: Infection Biology, Vaccination, Clinical Management

Editor(s): Matthias Frosch, Martin C. J. Maiden

Published Online: 29 JUN 2006

Print ISBN: 9783527312603

Online ISBN: 9783527608508

DOI: 10.1002/3527608508

About this Book

A comprehensive overview of recent advances, from current basic research and epidemiology, to novel therapeutic strategies and clinical management. Here, the leading scientists who have made major advances in the field provide up-to-date reviews and describe their current knowledge and concepts.
As such, this is the first volume to summarize the implications of the meningococcus genome-sequencing project, emphasizing the novel strategies in vaccine development. Following a look at the history, the authors go on to treat the epidemiology of meningococcal disease, as well as the genetics, structure and function of virulence factors. Further chapters cover cross-talk between meningococci and host cells, genomics and immunobiology.
The result is a standard handbook for all scientists working in the field. While aimed at advanced specialists in basic research, epidemiologists, public health workers, vaccine developers and clinicians, the book is equally appropriate as introductory reading for graduates embarking on their career in this field.

Table of contents

    1. You have free access to this content
    1. You have free access to this content
  1. Part I: Epidemiology of Meningococcal Disease

    1. Chapter 3

      Methods for Typing of Meningococci (pages 37–52)

      Keith A. Jolley, Steve J. Gray, Janet Suker and Rachel Urwin

  2. Part II: Genetics and Genomics of the Meningococcus

  3. Part III: Infection Biology

  4. Part IV: Development of Vaccines

    1. Chapter 18

      Outer Membrane Vesicle-based Meningococcal Vaccines (pages 371–390)

      Jan T. Poolman, Philippe Denoël, Christiane Feron, Karine Goraj and Vincent Weynants

    2. Chapter 19

      Genome Mining and Reverse Vaccinology (pages 391–402)

      Rosanna Leuzzi, Silvana Savino, Mariagrazia Pizza and Rino Rappuoli

  5. Part V: Clinical and Public Health Management

    1. You have free access to this content

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