High-Throughput Screening in Drug Discovery, Volume 35

High-Throughput Screening in Drug Discovery, Volume 35

Editor(s): Jörg Hüser

Published Online: 5 OCT 2006

Print ISBN: 9783527312832

Online ISBN: 9783527609321

DOI: 10.1002/3527609326

Series Editor(s): Raimund Mannhold, Hugo Kubinyi, Gerd Folkers

About this Book

Backed by leading authorities, this is a professional guide to successful compound screening in pharmaceutical research and chemical biology, including the chemoinformatic tools needed for correct data evaluation. Chapter authors from leading pharmaceutical companies as well as from Harvard University discuss such factors as chemical genetics, binding, cell-based and biochemical assays, the efficient use of compound libraries and data mining using cell-based assay results.
For both academics and professionals in the pharma and biotech industries working on small molecule screening.

Table of contents

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  1. Part I: Concept of Screening

    1. Chapter 2

      High-throughput Screening for Targeted Lead Discovery (pages 15–36)

      Jörg Hüser, Emanuel Lohrmann, Bernd Kalthof, Nils Burkhardt, Ulf Brüggemeier and Martin Bechem

  2. Part II: Automation Technologies

  3. Part III: Assay Technologies

    1. Chapter 5

      Biochemical Assays for High-throughput Screening (pages 93–128)

      William D. Mallender, Michael Bembenek, Lawrence R. Dick, Michael Kuranda, Ping Li, Saurabh Menon, Eneida Pardo and Tom Parsons

  4. Part IV: Data Analysis

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    1. You have free access to this content

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